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Global Cardiology

eISSN 2975-2728

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Editor-in-Chief: Andrew J.S. Coats, Australia

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  • The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

    Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus
    2025-06-30
    https://doi.org/10.4081/cardio.2025.67
    2769
    PDF: 574
    HTML: 143
  • Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

    Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker
    2023-12-27
    https://doi.org/10.4081/cardio.2023.15
    2835
    pdf: 776
    HTML: 49
  • Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

    Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek
    2024-06-28
    https://doi.org/10.4081/cardio.2024.39
    1803
    PDF: 564
    HTML: 13
  • Detection of early heart failure with preserved ejection fraction in metabolic syndrome patients detected as part of a national screening program in middle aged subjects

    Jelena Čelutkienė, Agnė Monika Jakštaitė, Jolita Badarienė, Svetlana Solovjova, Ieva Slivovskaja, Rokas Navickas, Edita Kazėnaitė, Egidija Rinkūnienė, Alma Čypienė, Jonas Misiūra, Ligita Ryliškytė, Aleksandras Laucevičius, Andrew J.S. Coats
    2023-12-29
    https://doi.org/10.4081/cardio.2023.3
    1763
    pdf: 341
    HTML: 13
  • Modulation of cardiac metabolism in heart failure

    Giuseppe M.C. Rosano, Andrew J.S. Coats
    2024-11-05
    https://doi.org/10.4081/cardio.2024.30
    2541
    PDF: 1246
    HTML: 71
  • Effect of metformin and empagliflozin on myocardial function in insulin-resistant patients with heart failure: rationale and design of the METRIS-HF-DZHK18 Trial

    Wolfram Doehner, Tim Friede, Frank Edelmann, Ulf Landmesser, Sebastian Winkler, Burkert Pieske, Fabian Knebel, Sebastian Kelle, Diethelm Tschöpe, Antje Meyer, Nadja Jauert, Marius Placzek, Jeanette Schulz-Menger, Stephan von Haehling, Stefan D. Anker
    2025-12-31
    https://doi.org/10.4081/cardio.2025.89
    392
    PDF: 123
    Appendix: 40
    HTML: 11
  • iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

    Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano
    2025-09-30
    https://doi.org/10.4081/cardio.2025.86
    3324
    PDF: 3195
    Supplementary: 394
    Appendix: 321
  • Clinical trial design, endpoints and regulatory considerations in heart failure

    Giuseppe M.C. Rosano
    2024-03-28
    https://doi.org/10.4081/cardio.2024.18
    5911
    PDF: 548
    HTML: 69
  • Iron supplementation in heart failure and iron deficiency: does it help?

    Laibah Arshad Khan, Syed Sarmad Javaid, Javed Butler
    2025-09-30
    https://doi.org/10.4081/cardio.2025.82
    850
    PDF: 464
    HTML: 75
  • The muscle hypothesis of shortness of breath in patients with cachexia

    Stefan D. Anker, Muhammad Shahzeb Khan, Laibah Arshad Khan, Giuseppe M.C. Rosano, Maurizio Volterrani, Mitja Lainscak, Piotr Ponikowski, Andrew J.S. Coats
    2024-12-30
    https://doi.org/10.4081/cardio.2024.57
    3164
    PDF: 905
    HTML: 42
  • Obesity and left atrial function: state of the art

    Ahmed Mustafa Rashid, Muhammad Shahzeb Khan, Fawaz Alenezi, Stefan D. Anker, Fabian Knebel
    2026-03-31
    https://doi.org/10.4081/cardio.2026.96
    818
    PDF: 283
    HTML: 96
  • Advanced cancer as a heart failure like syndrome due to cardiac wasting cardiomyopathy: facts and numbers

    Muhammad Shahzeb Khan, Javed Butler, Laibah Arshad Khan, Markus S. Anker
    2024-12-30
    https://doi.org/10.4081/cardio.2024.58
    3564
    PDF: 647
    HTML: 114
  • Cardiac wasting in patients with advanced cancer: state of the art review

    Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker
    2025-04-16
    https://doi.org/10.4081/cardio.2025.65
    2858
    PDF: 689
    HTML: 71
  • Glucagon-like peptide-1 receptor agonists and muscle: interpreting lean mass changes in clinical care

    Muhammad Sameer Arshad, Maaz Ali, Asad Ali Ahmed Cheema, Stefan D. Anker, Andrew J.S. Coats
    2026-03-31
    https://doi.org/10.4081/cardio.2026.101
    1185
    PDF: 379
    HTML: 128
  • Demographic and regional trends of heart failure and cachexia-related mortality among older adults in the United States, from 1999 to 2020

    Ishaque Hameed, Muhammad Nashit, Zahra Quettawala Mufaddal, Syed Sarmad Javaid, Muhammad Hanif
    2025-09-19
    https://doi.org/10.4081/cardio.2025.83
    487
    PDF: 288
    HTML: 72
  • Aortic valve replacement in asymptomatic severe aortic stenosis. A focused review

    Aimen Shafiq, Rohan Dev Trehan, Mitja Lainscak, Sanjeev Trehan
    2025-12-31
    https://doi.org/10.4081/cardio.2025.93
    371
    PDF: 158
    HTML: 20
  • Biological plausibility and implications of obesity associated valvular heart diseases

    Francesco Fioretti, Brian R. Lindman, Javed Butler
    2024-11-05
    https://doi.org/10.4081/cardio.2024.49
    2834
    PDF: 856
    HTML: 30
  • The effect of SGLT2 inhibitors on health status in patients with heart failure: a systematic review and meta-analysis

    Muhammad Shariq Usman, Arsalan Hamid, Shurjeel Uddin Qazi, Mikhail N. Kosiborod, Deepak L. Bhatt, Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler
    2024-06-28
    https://doi.org/10.4081/cardio.2024.35
    3168
    PDF: 760
    Conflict of interest: 350
    SUPPLEMENTARY MATERIAL: 294
    HTML: 86
  • Treatment pathways in patients with heart failure with preserved ejection fraction and obesity: perspectives from cardiology specialists and patients

    Javed Butler, Sanjiv J. Shah, Melissa Magwire, Carlos Campos, Muhammad Shariq Usman, Anthony Hoovler, Anup Sabharwal, Barry A. Borlaug
    2024-06-28
    https://doi.org/10.4081/cardio.2024.38
    2241
    PDF: 651
    SUPPLEMENTARY MATERIAL: 340
    GRAPHICAL ABSTRACT: 289
    HTML: 53
  • The scientific targets: the myocardium, the vasculature and the body’s response to heart failure

    Rafael Vidal-Pérez, Ewa A. Jankowska
    2024-03-28
    https://doi.org/10.4081/cardio.2024.19
    2869
    PDF: 299
    HTML: 25
  • Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

    Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf
    2025-08-20
    https://doi.org/10.4081/cardio.2025.78
    602
    PDF: 468
    Appendix: 247
    HTML: 70
  • Preliminary study on the immunohistochemical expression of galectin-3 in hypertrophic hearts

    Cecilia Salzillo, Lorenzo Giovannico, Giuseppe Fischetti, Gerardo Cazzato, Mario Magistro, Grazia Nucci, Gabriella Serio, Andrea Marzullo
    2024-06-28
    https://doi.org/10.4081/cardio.2024.37
    1516
    PDF: 396
    HTML: 27
  • Defining iron replete status in patients with heart failure treated with intravenous iron

    Khawaja M. Talha, Javed Butler, Stephan von Haehling, Mitja Lainscak, Piotr Ponikowski, Stefan D. Anker
    2023-12-21
    https://doi.org/10.4081/cardio.2023.17
    3315
    pdf: 450
    HTML: 69
  • Bridging the gap: integrating stress echocardiography, iFR, CFR, and FFR in the evaluation of coronary artery disease

    Konstantinos Stamos, Theodora Delaporta, Antonios Delaportas
    2025-04-16
    https://doi.org/10.4081/cardio.2025.66
    1603
    PDF: 547
    HTML: 0
  • Global Cardiology issue highlights

    Andrew J.S. Coats
    2024-06-28
    https://doi.org/10.4081/cardio.2024.41
    3611
    PDF: 455
    HTML: 0
  • The impact of frailty on in-hospital outcomes in patients with HFrEF

    Saad Ahmed Waqas, Taimor Mohammed Khan, Ahmed Kamal Siddiqi, Shahzad Hassan, Stefan D. Anker
    2025-12-17
    https://doi.org/10.4081/cardio.2025.88
    564
    PDF: 193
    Supplementary: 62
    HTML: 21
1 - 26 of 26 items

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iCARDIO

May 1 marked the release of the #iCARDIO Guidelines on Heart Failure, now live in Global Cardiology. This global-first effort brings flexible, practical guidance to frontline providers managing #heartfailure in any setting. www.globalcardiology.info/site/article... #GlobalHealth #cardiosky

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— iCardio (@icardio.bsky.social) May 13, 2025 at 8:26

Keywords

Vol. 4 No. 1 (2026)
Draft Document for Public Consultation: iCARDIO Alliance Global Implementation Guidelines on Ischemic Heart Disease Management 2026

Ischemic heart disease (IHD) remains the leading cause of morbidity and mortality worldwide.  Coronary artery disease (CAD) encompasses any pathological process capable of compromising myocardial perfusion and although numerous etiologies exist, including vasculitis, spontaneous coronary artery dissection, and coronary embolism, the majority of CAD is attributable to coronary atherosclerosis, which constitutes the focus of this document. For practical purposes, CAD is considered present when any degree of atherosclerotic involvement...

Writing Task Force | iCARDIO-Alliance
5 February 2026
Vol. 4 No. 1 (2026)
Metabolic dysfunction-associated steatotic liver disease and cardiovascular disease: a state-of-the-art review

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly nonalcoholic fatty liver disease, is the most prevalent chronic liver disease worldwide, affecting more than 30% of adults and up to 70–90% of individuals with obesity or type 2 diabetes mellitus. Cardiovascular disease (CVD) represents the leading cause of mortality in this population. MASLD is increasingly recognized as an independent cardiovascular risk factor beyond traditional metabolic comorbidities. This narrative review summarizes epidemiologic,...

Aimen Shafiq et al.
10 April 2026
Global Cardiology

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