Editorials
5 November 2024
Vol. 2 No. 3 (2024)
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To clip or not to clip moderate-to-severe functional mitral regurgitation in patients with heart failure?
Functional mitral regurgitation (FMR) is associated with a poor prognosis, with one-year mortality rates ranging from 15% to 40%.
1. Vajapey R, Kwon D. Guide to functional mitral regurgitation: a contemporary review. Cardiovasc Diagn Ther 2021;11:781-92. DOI: https://doi.org/10.21037/cdt-20-277
2. van der Bijl P, Khidir M, Ajmone Marsan N, et al. Effect of functional mitral regurgitation on outcome in patients receiving cardiac resynchronization therapy for heart failure. Am J Cardiol 2019;123:7583. DOI: https://doi.org/10.1016/j.amjcard.2018.09.020
3. Anker SD, Friede T, von Bardeleben RS, et al. Percutaneous repair of moderate-to-severe or severe functional mitral regurgitation in patients with symptomatic heart failure: Baseline characteristics of patients in the RESHAPE-HF2 trial and comparison to COAPT and MITRA-FR trials. Eur J Heart Fail 2024; 26:160815. DOI: https://doi.org/10.1002/ejhf.3286
4. Stone GW, Lindenfeld J, Abraham WT, et al. Transcatheter Mitral-Valve Repair in Patients with Heart Failure. N Engl J Med. 2018;379:2307-18. DOI: https://doi.org/10.1056/NEJMoa1806640
5. Obadia JF, Messika-Zeitoun D, Leurent G, et al. Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation. N Engl J Med 2018;379:2297-306. DOI: https://doi.org/10.1056/NEJMoa1805374
6. Pibarot P, Delgado V, Bax JJ. MITRA-FR vs. COAPT: lessons from two trials with diametrically opposed results. Eur Heart J Cardiovasc Imaging 2019;20:620-4. DOI: https://doi.org/10.1093/ehjci/jez073
7. Grayburn PA, Chandrashekhar YS. Functional Mitral Regurgitation: More Questions Than Answers. JACC Cardiovasc Imaging 2021;14:7114. DOI: https://doi.org/10.1016/j.jcmg.2021.03.001
8. Anker SD, Friede T, von Bardeleben RS, et al. Randomized investigation of the MitraClip device in heart failure: Design and rationale of the RESHAPE-HF2 trial design. Eur J Heart Fail 2024;26:98493. DOI: https://doi.org/10.1002/ejhf.3247
9. von Bardeleben RS, Khan MS, Geyer M, et al. Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR. Glob Cardiol 2024;2:40. DOI: https://doi.org/10.4081/cardio.2024.40
10. Anker SD, Butler J, Talha KM, Friede T. Using multiple primary endpoints in clinical trials with a focus on heart failure. Glob Cardiol 2024;2:33. DOI: https://doi.org/10.4081/cardio.2024.33
How to Cite
To clip or not to clip moderate-to-severe functional mitral regurgitation in patients with heart failure?. (2024). Global Cardiology, 2(3). https://doi.org/10.4081/cardio.2024.44
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