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Global Cardiology

eISSN 2975-2728

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Editor-in-Chief: Andrew J.S. Coats, Australia

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  • Relaxin-2 for heart failure with preserved ejection fraction: a comment on the termination of a phase-II trial investigating the relaxin-2 analogue, LY3540378

    Thomas Bernd Dschietzig, Guy Salama
    2024-12-30
    https://doi.org/10.4081/cardio.2024.56
    5024
    PDF: 1044
    HTML: 135
  • Lipoprotein(a): what clinicians need to know

    Laibah Arshad Khan, Muhammad Hanif, Ahmed Mustafa Rashid
    2025-09-01
    https://doi.org/10.4081/cardio.2025.80
    1482
    PDF: 1509
    HTML: 40
  • Global Cardiology issue highlights

    Andrew J.S. Coats
    2024-06-28
    https://doi.org/10.4081/cardio.2024.41
    3656
    PDF: 511
    HTML: 0
  • The Global Implementation Guidelines Initiative: how to optimize cardio-renal-metabolic care worldwide

    Fausto J. Pinto, Stefan D. Anker, William T. Abraham, John J. Atherton, Javed Butler, Vijay Chopra, Andrew J.S. Coats, Yann Colardelle, Maria Rosa Costanzo, Veronica Dean, Gerasimos Filippatos, Martha Gulati, Julio Rosenstock, John Teerlink, Subodh Verma, Jose Luis Zamorano, Yuhui Zhang, Shelley Zieroth
    2025-04-16
    https://doi.org/10.4081/cardio.2025.68
    4889
    PDF: 798
    Appendix: 533
    HTML: 57
  • Welcome to Global Cardiology

    Andrew J.S. Coats
    2023-12-20
    https://doi.org/10.4081/cardio.2023.1
    2682
    pdf: 264
    HTML: 4
  • Evolving targets for heart failure: the journey so far

    Giuseppe M.C. Rosano, Jerneja Farkas
    2023-11-28
    https://doi.org/10.4081/cardio.2023.6
    2434
    pdf: 525
    HTML: 4
  • To clip or not to clip moderate-to-severe functional mitral regurgitation in patients with heart failure?

    Muhammad Shahzeb Khan, Javed Butler, Tim Friede, Piotr Ponikowski, Stefan D. Anker
    2024-11-05
    https://doi.org/10.4081/cardio.2024.44
    3170
    PDF: 938
    HTML: 45
  • Large language models to write scientific manuscripts: to be considered but not trusted

    Christian Basile, Stefan D. Anker, Gianluigi Savarese
    2025-06-30
    https://doi.org/10.4081/cardio.2025.74
    984
    PDF: 431
    HTML: 20
  • Importance of patient-reported outcomes in cardiovascular illnesses

    Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan
    2025-06-30
    https://doi.org/10.4081/cardio.2025.69
    2488
    PDF: 643
    HTML: 202
  • Treatment pathways in patients with heart failure with preserved ejection fraction and obesity: perspectives from cardiology specialists and patients

    Javed Butler, Sanjiv J. Shah, Melissa Magwire, Carlos Campos, Muhammad Shariq Usman, Anthony Hoovler, Anup Sabharwal, Barry A. Borlaug
    2024-06-28
    https://doi.org/10.4081/cardio.2024.38
    2510
    PDF: 1127
    SUPPLEMENTARY MATERIAL: 395
    GRAPHICAL ABSTRACT: 326
    HTML: 214
  • Ten-year survival after indirect mitral annuloplasty with the Carillon Mitral Contour System in functional mitral regurgitation. A single-center followup from the REDUCE-FMR trial

    Janusz Lipiecki, Piotr Kalmucki, Larry E. Miller, Nicolas Durel
    2026-06-26
    https://doi.org/10.4081/cardio.2026.106
    358
    PDF: 138
    HTML: 30
  • Clinical trial design, endpoints and regulatory considerations in heart failure

    Giuseppe M.C. Rosano
    2024-03-28
    https://doi.org/10.4081/cardio.2024.18
    6062
    PDF: 642
    HTML: 69
  • Advanced cancer as a heart failure like syndrome due to cardiac wasting cardiomyopathy: facts and numbers

    Muhammad Shahzeb Khan, Javed Butler, Laibah Arshad Khan, Markus S. Anker
    2024-12-30
    https://doi.org/10.4081/cardio.2024.58
    3698
    PDF: 786
    HTML: 131
  • Beyond trial neutrality: treatment discontinuation and the hidden signal in SPIRIT-HF trial

    Viana Copeland, Andrew J.S. Coats
    2026-03-31
    https://doi.org/10.4081/cardio.2026.100
    1444
    PDF: 411
    HTML: 219
  • Glucagon-like peptide-1 receptor agonists and muscle: interpreting lean mass changes in clinical care

    Muhammad Sameer Arshad, Maaz Ali, Asad Ali Ahmed Cheema, Stefan D. Anker, Andrew J.S. Coats
    2026-03-31
    https://doi.org/10.4081/cardio.2026.101
    1405
    PDF: 578
    HTML: 172
  • Defining iron replete status in patients with heart failure treated with intravenous iron

    Khawaja M. Talha, Javed Butler, Stephan von Haehling, Mitja Lainscak, Piotr Ponikowski, Stefan D. Anker
    2023-12-21
    https://doi.org/10.4081/cardio.2023.17
    3395
    pdf: 585
    HTML: 83
  • Biological plausibility and implications of obesity associated valvular heart diseases

    Francesco Fioretti, Brian R. Lindman, Javed Butler
    2024-11-05
    https://doi.org/10.4081/cardio.2024.49
    3039
    PDF: 973
    HTML: 43
1 - 17 of 17 items

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iCARDIO

May 1 marked the release of the #iCARDIO Guidelines on Heart Failure, now live in Global Cardiology. This global-first effort brings flexible, practical guidance to frontline providers managing #heartfailure in any setting. www.globalcardiology.info/site/article... #GlobalHealth #cardiosky

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— iCardio (@icardio.bsky.social) May 13, 2025 at 8:26

Keywords

New papers
What is new and what has changed in the 2026 Global Heart Failure Implementation Guidelines and why

This 2026 focused update of the original iCARDIO Alliance Global Implementation Guidelines on Heart Failure published in 2025 incorporates emerging evidence relevant to acute and chronic HF, including heart failure with reduced ejection fraction (HFrEF), heart failure with preserved ejection fraction (HFpEF), and cardiomyopathies. When patients with HFrEF experience substantial improvement in LVEF they are commonly diagnosed as having HF with improved EF (HFimpEF). We define HFimpEF to be present, when in a patient who previously was...

Vijay Chopra et al.
24 August 2026
New papers
2026 iCARDIO Alliance Global Implementation Guidelines on Heart Failure

This is the updated 2026 version of the iCARDIO Alliance Global Implementation Guidelines on Heart Failure – originally published in 2025. In these guidelines, we aim to consider inconsistencies in healthcare access, varying infrastructure, resource constraints and diverse local practices as well as practical and political issues that restrict the global applicability of currently available guidelines. There is a need for universal recommendations that address the unique challenges faced by patients and healthcare providers worldwide. Our...

Vijay Chopra et al.
24 August 2026
New papers
iCARDIO Alliance Global Implementation Guidelines on Ischemic Heart Disease 2026

There are a number of guidelines on how to manage ischemic heart disease (IHD), but inconsistencies in healthcare access, varying infrastructure, resource constraints and diverse local practices restrict their global applicability. This underscores the need for universal recommendations that address the unique challenges faced by patients and healthcare providers worldwide. Our Global Guidelines emphasize the incorporation of novel therapies, while integrating standards of care with the most up-to-date evidence to enable clinicians to...

Fausto J. Pinto et al.
24 August 2026
Global Cardiology

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