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Global Cardiology

eISSN 2975-2728

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Editor-in-Chief: Andrew J.S. Coats, Australia

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  • Cardiac wasting in patients with advanced cancer: state of the art review

    Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker
    2025-04-16
    https://doi.org/10.4081/cardio.2025.65
    2344
    PDF: 438
    HTML: 25
  • The impact of diurnal fasting during Ramadan on patients with established cardiac disease: a systematic review

    Marwan M. Refaat, Nadim El Jamal, Hebah M. El-Rayess, Anthony Gebran, Amar M. Salam
    2024-06-28
    https://doi.org/10.4081/cardio.2024.32
    2263
    PDF: 759
    HTML: 14
  • The impact of maternal congenital heart disease on pregnancy outcomes in Malta: a retrospective study

    Maryanne Caruana, Miriam Gatt, Oscar Aquilina, Charles Savona Ventura, Victor Grech, Jane Somerville
    2023-12-29
    https://doi.org/10.4081/cardio.2023.14
    1478
    pdf: 130
    HTML: 2
  • Intervention options: depression and cardiovascular disease during COVID-19

    Eirini Flouda, Athena Stefanatou, Tinia Apergi
    2023-11-28
    https://doi.org/10.4081/cardio.2023.5
    1748
    pdf: 233
    HTML: 19
  • Prognostic factors and outcome in patients submitted into coronary artery bypass surgery with total arterial myocardial revascularization

    Elias Tassoulas, Dimitrios Tasoulas, Christos Papaconstantinou, Ioannis Chlorogiannis
    2024-12-30
    https://doi.org/10.4081/cardio.2024.46
    2584
    PDF: 436
    HTML: 15
  • Lipoprotein(a): what clinicians need to know

    Laibah Arshad Khan, Muhammad Hanif, Ahmed Mustafa Rashid
    2025-09-01
    https://doi.org/10.4081/cardio.2025.80
    230
    PDF: 559
    HTML: 23
  • Modulation of cardiac metabolism in heart failure

    Giuseppe M.C. Rosano, Andrew J.S. Coats
    2024-11-05
    https://doi.org/10.4081/cardio.2024.30
    2314
    PDF: 1131
    HTML: 20
  • Advanced cancer as a heart failure like syndrome due to cardiac wasting cardiomyopathy: facts and numbers

    Muhammad Shahzeb Khan, Javed Butler, Laibah Arshad Khan, Markus S. Anker
    2024-12-30
    https://doi.org/10.4081/cardio.2024.58
    2991
    PDF: 509
    HTML: 41
  • Rationale and design for the peripartum cardiomyopathy in Nigeria (PEACE) registry

    Kamilu M. Karaye, Idris Y. Mohammed, Okechukwu S. Ogah, Basil N. Okeahialam
    2023-11-28
    https://doi.org/10.4081/cardio.2023.4
    969
    pdf: 219
    HTML: 42
  • iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

    Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano
    2025-09-30
    https://doi.org/10.4081/cardio.2025.86
    818
    PDF: 2302
    Supplementary: 305
    Appendix: 251
  • Epidemiology of peripartum cardiomyopathy in Africa

    Kamilu M. Karaye, Abdulrazaq G. Habib, Karen Sliwa
    2024-06-28
    https://doi.org/10.4081/cardio.2024.31
    2194
    PDF: 488
    HTML: 79
  • COVID-19 myocarditis

    Reinaldo B. Bestetti, Rosemary Furlan-Daniel, Luciano P. Pereira
    2024-03-28
    https://doi.org/10.4081/cardio.2024.21
    2651
    PDF: 215
    HTML: 14
  • Quality of life in Maltese adults with congenital heart disease: a second look An APPROACH-IS substudy

    Maryanne Caruana, Philip Moons, Adrienne H. Kovacs, Koen Luyckx, Corina Thomet, Werner Budts, Maayke Sluman, Katrine Eriksen, Mikael Dellborg, Malin Berghammer, Bengt Johansson, Alexandra Soufi, Edward Callus, Victor Grech, Silke Apers
    2024-03-28
    https://doi.org/10.4081/cardio.2024.26
    1611
    PDF: 149
    HTML: 9
  • The muscle hypothesis of shortness of breath in patients with cachexia

    Stefan D. Anker, Muhammad Shahzeb Khan, Laibah Arshad Khan, Giuseppe M.C. Rosano, Maurizio Volterrani, Mitja Lainscak, Piotr Ponikowski, Andrew J.S. Coats
    2024-12-30
    https://doi.org/10.4081/cardio.2024.57
    2454
    PDF: 635
    HTML: 8
  • Evaluating serum galectin-3 binding protein as a diagnostic and prognostic biomarker in pulmonary arterial hypertension: a comparative study

    Arif Albulushi, Lama S. Alfehaid, Mosaad Alhussein, Amr Youssef
    2024-12-30
    https://doi.org/10.4081/cardio.2024.50
    1726
    PDF: 452
    HTML: 3
  • Is the obesity paradox present in left ventricular assist device recipients? A BMI-based analysis

    Saad Ahmed Waqas, Hibah Siddiqui, Faouzi Kallel, Shahzad Hassan
    2025-09-30
    https://doi.org/10.4081/cardio.2025.84
    127
    PDF: 206
    Supplementary: 142
    HTML: 17
  • Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

    Christian Basile, Stefan D. Anker, Gianluigi Savarese
    2025-06-30
    https://doi.org/10.4081/cardio.2025.73
    730
    PDF: 197
    Supplementary: 140
    Appendix: 110
    HTML: 21
  • The scientific targets: the myocardium, the vasculature and the body’s response to heart failure

    Rafael Vidal-Pérez, Ewa A. Jankowska
    2024-03-28
    https://doi.org/10.4081/cardio.2024.19
    2634
    PDF: 191
    HTML: 21
  • Preliminary study on the immunohistochemical expression of galectin-3 in hypertrophic hearts

    Cecilia Salzillo, Lorenzo Giovannico, Giuseppe Fischetti, Gerardo Cazzato, Mario Magistro, Grazia Nucci, Gabriella Serio, Andrea Marzullo
    2024-06-28
    https://doi.org/10.4081/cardio.2024.37
    1298
    PDF: 315
    HTML: 10
  • Bridging the gap: integrating stress echocardiography, iFR, CFR, and FFR in the evaluation of coronary artery disease

    Konstantinos Stamos, Theodora Delaporta, Antonios Delaportas
    2025-04-16
    https://doi.org/10.4081/cardio.2025.66
    1261
    PDF: 239
    HTML: 0
  • Prevalence of left ventricular dysfunction and relationship with serum selenium in apparently healthy pregnant women: results from the PEACE registry

    Kamilu M. Karaye, Idris Y. Mohammed, Hadiza Sa’idu, Naser A. Ishaq, Suleiman A. Balarabe, Jamilu Tukur, Tewogbade A. Adedeji, Olufemiwa N. Makinde, Rasaaq A. Adebayo
    2024-06-28
    https://doi.org/10.4081/cardio.2024.36
    1575
    PDF: 379
    HTML: 1
  • Elevated endostatin is associated with hypertension treatment, elevated high sensitivity C-reactive protein, increased waist-hip ratio, and attenuated kidney function, but not with age, in a middle-aged population

    Anders Larsson, Bertil Wegmann, Toralph Ruge, Joakim Alfredsson, Carl Johan Östgren, Tomas Lindahl
    2025-04-16
    https://doi.org/10.4081/cardio.2025.64
    2377
    PDF: 448
    HTML: 2
  • Bibliometric analysis of cardiovascular disease research activity in the Arab world

    Hussein H. Khachfe, Marwan M. Refaat
    2024-06-28
    https://doi.org/10.4081/cardio.2024.34
    1903
    PDF: 522
    HTML: 5
  • Importance of patient-reported outcomes in cardiovascular illnesses

    Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan
    2025-06-30
    https://doi.org/10.4081/cardio.2025.69
    1940
    PDF: 404
    HTML: 89
  • Applicability of obesity clinical practice guidelines in low- and middle-income countries

    Shelley Zieroth, Fausto Pinto, Stefan D. Anker, William T. Abraham, John J. Atherton, Javed Butler, Vijay Chopra, Andrew J.S. Coats, Martha Gulati, Tammy L. Kindel, José Luis Zamorano, Yuhui Zhang, Linong Ji, Yann Colardelle, Richard B. Weiskopf
    2025-06-30
    https://doi.org/10.4081/cardio.2025.77
    986
    PDF: 513
    Appendix: 136
    HTML: 13
  • AI-generated

    Unveiling the genetic aetiology of non-genetic dilated cardiomyopathy

    Emanuele Monda, Giuseppe Limongelli
    2024-12-30
    https://doi.org/10.4081/cardio.2024.54
    2395
    PDF: 410
    HTML: 5
  • Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

    Christian Basile, Stefan D. Anker, Gianluigi Savarese
    2025-07-16
    https://doi.org/10.4081/cardio.2025.76
    737
    PDF: 182
    Supplementary: 145
    Appendix: 104
    HTML: 24
  • Detection of early heart failure with preserved ejection fraction in metabolic syndrome patients detected as part of a national screening program in middle aged subjects

    Jelena Čelutkienė, Agnė Monika Jakštaitė, Jolita Badarienė, Svetlana Solovjova, Ieva Slivovskaja, Rokas Navickas, Edita Kazėnaitė, Egidija Rinkūnienė, Alma Čypienė, Jonas Misiūra, Ligita Ryliškytė, Aleksandras Laucevičius, Andrew J.S. Coats
    2023-12-29
    https://doi.org/10.4081/cardio.2023.3
    1530
    pdf: 199
    HTML: 5
  • Evolving targets for heart failure: the journey so far

    Giuseppe M.C. Rosano, Jerneja Farkas
    2023-11-28
    https://doi.org/10.4081/cardio.2023.6
    1967
    pdf: 309
    HTML: 4
  • Biological plausibility and implications of obesity associated valvular heart diseases

    Francesco Fioretti, Brian R. Lindman, Javed Butler
    2024-11-05
    https://doi.org/10.4081/cardio.2024.49
    2455
    PDF: 655
    HTML: 1
  • The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

    Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus
    2025-06-30
    https://doi.org/10.4081/cardio.2025.67
    2073
    PDF: 440
    HTML: 78
  • Elevated left ventricular end diastolic pressure, chronic pulmonary oedema and valve disease

    Prithwish Banerjee
    2024-04-08
    https://doi.org/10.4081/cardio.2024.23
    1912
    PDF: 150
    HTML: 666
  • Depression, health-related quality of life and life satisfaction in patients with heart failure

    Natasa Sedlar Kobe, Daniel Omersa, Mitja Lainscak, Jerneja Farkas
    2024-11-05
    https://doi.org/10.4081/cardio.2024.47
    2771
    PDF: 676
    HTML: 2
  • Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

    Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf
    2025-08-20
    https://doi.org/10.4081/cardio.2025.78
    308
    PDF: 314
    Appendix: 197
    HTML: 49
  • SGLT2 inhibitors and risk reduction for mortality in high-risk patients: a meta-analysis of randomized controlled trials

    Tariq Jamal Siddiqi, Javed Butler, Andrew J.S. Coats, Subodh Verma, Tim Friede, Gerasimos Filippatos, Stefan D. Anker
    2023-11-23
    https://doi.org/10.4081/cardio.2023.2
    1052
    pdf: 234
    Supplementary Material: 38
    HTML: 103
  • Impella vs intra-aortic balloon pump in patients with acute myocardial infarction complicated with cardiogenic shock: an updated systematic review and meta-analysis

    Muhammad Ahmed, Serish Bano, Mutahira Asif, F.N.U. Sidra, Meva Ram, Shahida Bibi
    2025-04-16
    https://doi.org/10.4081/cardio.2025.61
    3188
    PDF: 685
    Supplementary: 374
    HTML: 0
  • Demographic and regional trends of heart failure and cachexia-related mortality among older adults in the United States, from 1999 to 2020

    Ishaque Hameed, Muhammad Nashit, Zahra Quettawala Mufaddal, Syed Sarmad Javaid, Muhammad Hanif
    2025-09-19
    https://doi.org/10.4081/cardio.2025.83
    153
    PDF: 186
    HTML: 26
  • New left ventricular thrombus and embolic events in left ventricular dysfunction postmyocardial infarction

    Ali A. Youssef, Shaima Al-Omani, Mustafa A. Alrefae, Ahmad Suliman, Reem Hassan, Omar Saleh, Zizi S. Khalifa
    2024-11-05
    https://doi.org/10.4081/cardio.2024.43
    1872
    PDF: 662
    HTML: 3
  • Anomalous origin of right coronary artery from the pulmonary artery: an incidental finding on cardiac computed tomography in a patient presenting with dyspnea

    Rachel Anne Xuereb, Sara Xuereb, Kentaro Yamagata, Robert George Xuereb
    2024-03-28
    https://doi.org/10.4081/cardio.2024.24
    1463
    PDF: 163
    HTML: 12
  • Clinical profiles and short-term outcomes of women with peripartum and dilated cardiomyopathies

    Babalawan Muhammad, Naser A. Ishaq, Kamilu M. Karaye
    2024-11-05
    https://doi.org/10.4081/cardio.2024.42
    2066
    PDF: 571
    HTML: 3
  • Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes

    Asad Gul Rao, Syed Sarmad Javaid, Ahmed Mustafa Rashid, Fawaz Alenezi
    2025-09-15
    https://doi.org/10.4081/cardio.2025.81
    233
    PDF: 304
    HTML: 73
  • Mavacamten’s therapeutic impact: cardiac-specific myosin inhibition in obstructive hypertrophic cardiomyopathy

    Ahmad Shabbir, Laiba Yumn, Esha Khan
    2024-11-05
    https://doi.org/10.4081/cardio.2024.48
    2273
    PDF: 584
    HTML: 0
  • Global Cardiology issue highlights

    Andrew J.S. Coats
    2024-06-28
    https://doi.org/10.4081/cardio.2024.41
    3452
    PDF: 394
    HTML: 0
  • Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

    Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker
    2024-06-28
    https://doi.org/10.4081/cardio.2024.40
    5271
    PDF: 721
    HTML: 23
  • Acute interventional management of spontaneous coronary artery dissection: case series and literature review

    Enrico Cerrato, Ilaria Meynet, Giorgio Quadri, Federico Giacobbe, Cristina Rolfo, Francesco Tomassini, Fabio Ferrari, Fabio Mariani, Luca Lo Savio, Matteo Bianco, Paola Destefanis, Alessia Luciano, Carol Gravinese, Emanuele Tizzani, Sara Giolitto, Antonella Corleto, Fabrizio D’Ascenzo, Umberto Barbero, Fernando Macaya, Javier Escaned, Roberto Pozzi, Ferdinando Varbella
    2024-03-28
    https://doi.org/10.4081/cardio.2024.22
    3835
    PDF: 174
    HTML: 36
  • The Global Implementation Guidelines Initiative: how to optimize cardio-renal-metabolic care worldwide

    Fausto J. Pinto, Stefan D. Anker, William T. Abraham, John J. Atherton, Javed Butler, Vijay Chopra, Andrew J.S. Coats, Yann Colardelle, Maria Rosa Costanzo, Veronica Dean, Gerasimos Filippatos, Martha Gulati, Julio Rosenstock, John Teerlink, Subodh Verma, Jose Luis Zamorano, Yuhui Zhang, Shelley Zieroth
    2025-04-16
    https://doi.org/10.4081/cardio.2025.68
    3293
    PDF: 500
    Appendix: 375
    HTML: 24
  • Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

    Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker
    2023-12-27
    https://doi.org/10.4081/cardio.2023.15
    2484
    pdf: 519
    HTML: 29
  • Using multiple primary endpoints in clinical trials with a focus on heart failure

    Stefan D. Anker, Javed Butler, Khawaja M. Talha, Tim Friede
    2024-06-28
    https://doi.org/10.4081/cardio.2024.33
    5458
    PDF: 709
    HTML: 162
  • Neck-to-height ratio in Bosnian university students according to the 2017 American College of Cardiology/American Heart Association guidelines on hypertension classification

    Asija Začiragić, Marija Mikić, Amela Dervišević, Orhan Lepara, Nesina Avdagić, Nermina Babić, Almir Fajkić, Amina Valjevac
    2024-03-28
    https://doi.org/10.4081/cardio.2024.27
    1848
    PDF: 210
    HTML: 12
  • Treatment pathways in patients with heart failure with preserved ejection fraction and obesity: perspectives from cardiology specialists and patients

    Javed Butler, Sanjiv J. Shah, Melissa Magwire, Carlos Campos, Muhammad Shariq Usman, Anthony Hoovler, Anup Sabharwal, Barry A. Borlaug
    2024-06-28
    https://doi.org/10.4081/cardio.2024.38
    1862
    PDF: 503
    SUPPLEMENTARY MATERIAL: 295
    GRAPHICAL ABSTRACT: 261
    HTML: 9
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iCARDIO

May 1 marked the release of the #iCARDIO Guidelines on Heart Failure, now live in Global Cardiology. This global-first effort brings flexible, practical guidance to frontline providers managing #heartfailure in any setting. www.globalcardiology.info/site/article... #GlobalHealth #cardiosky

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— iCardio (@icardio.bsky.social) May 13, 2025 at 8:26

Keywords

New papers
Coronary artery calcium scoring. What clinicians need to know

Coronary artery calcium (CAC) scoring, measured by computed tomography (CT), quantifies calcified coronary plaque and reflects the burden of coronary atherosclerosis. The Agatston score, calculated based on lesion density and area, stratifies patients into risk categories: a score of 0 indicates no detectable calcification, 1-99 suggests mild plaque, 100-399 indicates moderate burden, and scores of 400 or more reflect high to extensive calcification, with scores above 1000 indicate extremely high atherosclerotic burden. CAC scoring is...

Syeda Sundus Shah Bokharii et al.
11 December 2025
New papers
The impact of frailty on in-hospital outcomes in patients with HFrEF

Frailty is a marker of poor prognosis and is often undertreated and predisposed to adverse outcomes. This study aimed to determine the association between frailty and outcomes in hospitalized patients with heart failure with reduced ejection fraction (HFrEF). A retrospective cross-sectional analysis of the National Inpatient Sample (2016-2020) was conducted to evaluate hospitalizations for HFrEF. Frailty was defined as a hospital frailty risk score of ≥5. Patient demographics, comorbidities, and hospital characteristics were compared...

Saad Ahmed Waqas et al.
17 December 2025
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