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Bridging the gap between study outcomes and real-world results. Algorithm-driven management in a rural cardioMEMS population

Marc Atzenhoefer, Elizabeth Dille, Rebecca Steinke, Nicole Weigert, Keri Sabel, Kirsten Rasmussen

2025-04-16

https://doi.org/10.4081/cardio.2025.63

3137

PDF: 637

HTML: 19
The scientific targets: the myocardium, the vasculature and the body’s response to heart failure

Rafael Vidal-Pérez, Ewa A. Jankowska

2024-03-28

https://doi.org/10.4081/cardio.2024.19

2672

PDF: 205

HTML: 21
Modulation of cardiac metabolism in heart failure

Giuseppe M.C. Rosano, Andrew J.S. Coats

2024-11-05

https://doi.org/10.4081/cardio.2024.30

2346

PDF: 1147

HTML: 26
Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

Christian Basile, Stefan D. Anker, Gianluigi Savarese

2025-06-30

https://doi.org/10.4081/cardio.2025.73

764

PDF: 215

Supplementary: 142

Appendix: 111

HTML: 33
Evolving targets for heart failure: the journey so far

Giuseppe M.C. Rosano, Jerneja Farkas

2023-11-28

https://doi.org/10.4081/cardio.2023.6

2033

pdf: 326

HTML: 4
The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus

2025-06-30

https://doi.org/10.4081/cardio.2025.67

2143

PDF: 469

HTML: 99
Treatment pathways in patients with heart failure with preserved ejection fraction and obesity: perspectives from cardiology specialists and patients

Javed Butler, Sanjiv J. Shah, Melissa Magwire, Carlos Campos, Muhammad Shariq Usman, Anthony Hoovler, Anup Sabharwal, Barry A. Borlaug

2024-06-28

https://doi.org/10.4081/cardio.2024.38

1921

PDF: 519

SUPPLEMENTARY MATERIAL: 300

GRAPHICAL ABSTRACT: 265

HTML: 26
Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker

2024-06-28

https://doi.org/10.4081/cardio.2024.40

5342

PDF: 728

HTML: 28
Adherence to lifestyle therapy in patients with chronic heart failure and comorbidity

Elena Efremova, Alexander Shutov

2023-12-20

https://doi.org/10.4081/cardio.2023.8

1220

pdf: 254

HTML: 24
Clinical trial design, endpoints and regulatory considerations in heart failure

Giuseppe M.C. Rosano

2024-03-28

https://doi.org/10.4081/cardio.2024.18

5664

PDF: 457

HTML: 69
Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

Christian Basile, Stefan D. Anker, Gianluigi Savarese

2025-07-16

https://doi.org/10.4081/cardio.2025.76

776

PDF: 194

Supplementary: 151

Appendix: 105

HTML: 36
Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker

2023-12-27

https://doi.org/10.4081/cardio.2023.15

2538

pdf: 556

HTML: 30
Iron supplementation in heart failure and iron deficiency: does it help?

Laibah Arshad Khan, Syed Sarmad Javaid, Javed Butler

2025-09-30

https://doi.org/10.4081/cardio.2025.82

220

PDF: 295

HTML: 49
Cardiac wasting in patients with advanced cancer: state of the art review

Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker

2025-04-16

https://doi.org/10.4081/cardio.2025.65

2411

PDF: 486

HTML: 39
Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf

2025-08-20

https://doi.org/10.4081/cardio.2025.78

371

PDF: 345

Appendix: 208

HTML: 52
Defining iron replete status in patients with heart failure treated with intravenous iron

Khawaja M. Talha, Javed Butler, Stephan von Haehling, Mitja Lainscak, Piotr Ponikowski, Stefan D. Anker

2023-12-21

https://doi.org/10.4081/cardio.2023.17

2965

pdf: 314

HTML: 52
The association of iron deficiency with right ventricular dysfunction in Africans with heart failure

Adeseye A. Akintunde, Sope T. Orugun

2024-12-30

https://doi.org/10.4081/cardio.2024.53

2304

PDF: 390

Appendix B: 436

Appendix A: 318

HTML: 2
Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek

2024-06-28

https://doi.org/10.4081/cardio.2024.39

1520

PDF: 453

HTML: 4
iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano

2025-09-30

https://doi.org/10.4081/cardio.2025.86

1077

PDF: 28

Supplementary: 316

Appendix: 262
The effect of SGLT2 inhibitors on health status in patients with heart failure: a systematic review and meta-analysis

Muhammad Shariq Usman, Arsalan Hamid, Shurjeel Uddin Qazi, Mikhail N. Kosiborod, Deepak L. Bhatt, Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler

2024-06-28

https://doi.org/10.4081/cardio.2024.35

2483

PDF: 658

Conflict of interest: 320

SUPPLEMENTARY MATERIAL: 256

HTML: 61
Advanced cancer as a heart failure like syndrome due to cardiac wasting cardiomyopathy: facts and numbers

Muhammad Shahzeb Khan, Javed Butler, Laibah Arshad Khan, Markus S. Anker

2024-12-30

https://doi.org/10.4081/cardio.2024.58

3090

PDF: 539

HTML: 59
Demographic and regional trends of heart failure and cachexia-related mortality among older adults in the United States, from 1999 to 2020

Ishaque Hameed, Muhammad Nashit, Zahra Quettawala Mufaddal, Syed Sarmad Javaid, Muhammad Hanif

2025-09-19

https://doi.org/10.4081/cardio.2025.83

203

PDF: 198

HTML: 32
Using multiple primary endpoints in clinical trials with a focus on heart failure

Stefan D. Anker, Javed Butler, Khawaja M. Talha, Tim Friede

2024-06-28

https://doi.org/10.4081/cardio.2024.33

5522

PDF: 732

HTML: 194
The impact of maternal congenital heart disease on pregnancy outcomes in Malta: a retrospective study

Maryanne Caruana, Miriam Gatt, Oscar Aquilina, Charles Savona Ventura, Victor Grech, Jane Somerville

2023-12-29

https://doi.org/10.4081/cardio.2023.14

1529

pdf: 134

HTML: 2
Intervention options: depression and cardiovascular disease during COVID-19

Eirini Flouda, Athena Stefanatou, Tinia Apergi

2023-11-28

https://doi.org/10.4081/cardio.2023.5

1797

pdf: 247

HTML: 21
The impact of frailty on in-hospital outcomes in patients with HFrEF

Saad Ahmed Waqas, Taimor Mohammed Khan, Ahmed Kamal Siddiqi, Shahzad Hassan, Stefan D. Anker

2025-12-17

https://doi.org/10.4081/cardio.2025.88

128

PDF: 51

Supplementary: 10

HTML: 1
Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes

Asad Gul Rao, Syed Sarmad Javaid, Ahmed Mustafa Rashid, Fawaz Alenezi

2025-09-15

https://doi.org/10.4081/cardio.2025.81

337

PDF: 345

HTML: 122
Is the obesity paradox present in left ventricular assist device recipients? A BMI-based analysis

Saad Ahmed Waqas, Hibah Siddiqui, Faouzi Kallel, Shahzad Hassan

2025-09-30

https://doi.org/10.4081/cardio.2025.84

178

PDF: 230

Supplementary: 147

HTML: 21
Epidemiology of peripartum cardiomyopathy in Africa

Kamilu M. Karaye, Abdulrazaq G. Habib, Karen Sliwa

2024-06-28

https://doi.org/10.4081/cardio.2024.31

2267

PDF: 502

HTML: 95
Coronary artery calcium scoring. What clinicians need to know

Syeda Sundus Shah Bokharii, Cristiana Vitale, Eman Khan, Giuseppe M.C. Rosano, Laibah Arshad Khan

2025-12-11

https://doi.org/10.4081/cardio.2025.87

346

PDF: 160

HTML: 1
Relaxin-2 for heart failure with preserved ejection fraction: a comment on the termination of a phase-II trial investigating the relaxin-2 analogue, LY3540378

Thomas Bernd Dschietzig, Guy Salama

2024-12-30

https://doi.org/10.4081/cardio.2024.56

3975

PDF: 912

HTML: 81
Importance of patient-reported outcomes in cardiovascular illnesses

Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan

2025-06-30

https://doi.org/10.4081/cardio.2025.69

1972

PDF: 420

HTML: 105
iCARDIO Alliance Global Implementation Guidelines on Heart Failure 2025

Vijay Chopra, Muhammad Shahzeb Khan, Magdy Abdelhamid, William T. Abraham, Offer Amir, Stefan D. Anker, John J. Atherton, Fernando Bacal, Ralph Stephan von Bardeleben, Dulce Brito, Lucrecia Maria Burgos, Javed Butler, Maria Rosa Costanzo, Albertino Damasceno, Justin A. Ezekowitz, Ishaque Hameed, Sivadasanpillai Harikrishnan, Tiny Jaarsma, Anuradha Lala, Ileana L. Piña, Clara Saldarriaga, David Sim, John R. Teerlink, Nqoba Tsabedze, Hiroyuki Tsutsui, Jing Yu, Yuhui Zhang, Mohammad Zubaid, Nikhil Balankhe, Juan Esteban Gomez-Mesa, James L. Januzzi, Marvin Konstam, Rhonda Monroe, Elijah Ogola, Vinayagam Palaniappan, Mark C. Petrie, Fausto J. Pinto, Girish C. Rajadhyaksha, Amina Rakisheva, Carlos E. Ramos, Victor Rossel, Naoki Sato, P. Christian Schulze, Andrew Sindone, Hadi N. Skouri, Harriette G.C. Van Spall, Aistė Štaraitė, Lynne Warner Stevenson, Kadhim Sulaiman, Tzung-Dau Wang, Michael Böhm, Andrew J.S. Coats, Shelley Zieroth

2025-06-30

https://doi.org/10.4081/cardio.2025.70

11938

PDF: 7871

Appendix: 1045
To clip or not to clip moderate-to-severe functional mitral regurgitation in patients with heart failure?

Muhammad Shahzeb Khan, Javed Butler, Tim Friede, Piotr Ponikowski, Stefan D. Anker

2024-11-05

https://doi.org/10.4081/cardio.2024.44

3008

PDF: 772

HTML: 17
The muscle hypothesis of shortness of breath in patients with cachexia

Stefan D. Anker, Muhammad Shahzeb Khan, Laibah Arshad Khan, Giuseppe M.C. Rosano, Maurizio Volterrani, Mitja Lainscak, Piotr Ponikowski, Andrew J.S. Coats

2024-12-30

https://doi.org/10.4081/cardio.2024.57

2499

PDF: 683

HTML: 8
Biological plausibility and implications of obesity associated valvular heart diseases

Francesco Fioretti, Brian R. Lindman, Javed Butler

2024-11-05

https://doi.org/10.4081/cardio.2024.49

2524

PDF: 663

HTML: 3
SGLT2 inhibitors and risk reduction for mortality in high-risk patients: a meta-analysis of randomized controlled trials

Tariq Jamal Siddiqi, Javed Butler, Andrew J.S. Coats, Subodh Verma, Tim Friede, Gerasimos Filippatos, Stefan D. Anker

2023-11-23

https://doi.org/10.4081/cardio.2023.2

1114

pdf: 244

Supplementary Material: 39

HTML: 121
Clinical profiles and short-term outcomes of women with peripartum and dilated cardiomyopathies

Babalawan Muhammad, Naser A. Ishaq, Kamilu M. Karaye

2024-11-05

https://doi.org/10.4081/cardio.2024.42

2095

PDF: 576

HTML: 3
The impact of diurnal fasting during Ramadan on patients with established cardiac disease: a systematic review

Marwan M. Refaat, Nadim El Jamal, Hebah M. El-Rayess, Anthony Gebran, Amar M. Salam

2024-06-28

https://doi.org/10.4081/cardio.2024.32

2353

PDF: 813

HTML: 15
The Global Implementation Guidelines Initiative: how to optimize cardio-renal-metabolic care worldwide

Fausto J. Pinto, Stefan D. Anker, William T. Abraham, John J. Atherton, Javed Butler, Vijay Chopra, Andrew J.S. Coats, Yann Colardelle, Maria Rosa Costanzo, Veronica Dean, Gerasimos Filippatos, Martha Gulati, Julio Rosenstock, John Teerlink, Subodh Verma, Jose Luis Zamorano, Yuhui Zhang, Shelley Zieroth

2025-04-16

https://doi.org/10.4081/cardio.2025.68

3363

PDF: 532

Appendix: 390

HTML: 26
Rationale and design for the peripartum cardiomyopathy in Nigeria (PEACE) registry

Kamilu M. Karaye, Idris Y. Mohammed, Okechukwu S. Ogah, Basil N. Okeahialam

2023-11-28

https://doi.org/10.4081/cardio.2023.4

999

pdf: 229

HTML: 44
Applicability of obesity clinical practice guidelines in low- and middle-income countries

Shelley Zieroth, Fausto Pinto, Stefan D. Anker, William T. Abraham, John J. Atherton, Javed Butler, Vijay Chopra, Andrew J.S. Coats, Martha Gulati, Tammy L. Kindel, José Luis Zamorano, Yuhui Zhang, Linong Ji, Yann Colardelle, Richard B. Weiskopf

2025-06-30

https://doi.org/10.4081/cardio.2025.77

1124

PDF: 569

Appendix: 207

HTML: 17
Frequency of low-density-lipoprotein-cholesterol measurement and risk of major adverse cardiovascular outcomes: a 5-million-person nationwide cohort study

Denis M. Ngina, Wolfram Doehner, George Ntaios, Yvonne Nartey, Ralph K. Akyea

2025-09-30

https://doi.org/10.4081/cardio.2025.85

221

PDF: 439

HTML: 42
Global Cardiology issue highlights

Andrew J.S. Coats

2024-06-28

https://doi.org/10.4081/cardio.2024.41

3469

PDF: 400

HTML: 0
Bridging the gap: integrating stress echocardiography, iFR, CFR, and FFR in the evaluation of coronary artery disease

Konstantinos Stamos, Theodora Delaporta, Antonios Delaportas

2025-04-16

https://doi.org/10.4081/cardio.2025.66

1292

PDF: 279

HTML: 0
Safety and efficacy of left atrial appendage closure in cancer versus non-cancer patients: a systematic review and meta-analysis

Muhammad Ahmed, Fatima Muskan, Mohsin Zaheer, Manesh Kumar, Sawera Gul, Abdul Hadi Ansari, Muhammad Sameer Jamal, Muhammad Sohaib Asghar, M. Chadi Alraies, Shiny Teja Kolli, Praveen Kumar Komminni, Priya Hotwani, Vishal Reddy Bejugam

2025-06-30

https://doi.org/10.4081/cardio.2025.72

1112

PDF: 261

Supplementary: 159

HTML: 89
Effect of metformin and empagliflozin on myocardial function in insulin-resistant patients with heart failure: rationale and design of the METRIS-HF-DZHK18 Trial

Wolfram Doehner, Tim Friede, Frank Edelmann, Ulf Landmesser, Sebastian Winkler, Burkert Pieske, Fabian Knebel, Sebastian Kelle, Diethelm Tschöpe, Antje Meyer, Nadja Jauert, Marius Placzek, Jeanette Schulz-Menger, Stephan von Haehling, Stefan D. Anker

2025-12-31

https://doi.org/10.4081/cardio.2025.89

77

PDF: 22

Appendix: 4
Prevalence of left ventricular dysfunction and relationship with serum selenium in apparently healthy pregnant women: results from the PEACE registry

Kamilu M. Karaye, Idris Y. Mohammed, Hadiza Sa’idu, Naser A. Ishaq, Suleiman A. Balarabe, Jamilu Tukur, Tewogbade A. Adedeji, Olufemiwa N. Makinde, Rasaaq A. Adebayo

2024-06-28

https://doi.org/10.4081/cardio.2024.36

1599

PDF: 392

HTML: 2
Elevated endostatin is associated with hypertension treatment, elevated high sensitivity C-reactive protein, increased waist-hip ratio, and attenuated kidney function, but not with age, in a middle-aged population

Anders Larsson, Bertil Wegmann, Toralph Ruge, Joakim Alfredsson, Carl Johan Östgren, Tomas Lindahl

2025-04-16

https://doi.org/10.4081/cardio.2025.64

2410

PDF: 469

HTML: 3
Preferential vasodilator effects of levosimendan in resistance pulmonary arteries in a rodent pulmonary embolism model

Camila Bedo, Juan C. Grignola

2024-03-28

https://doi.org/10.4081/cardio.2024.25

1433

PDF: 170

HTML: 12

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