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Global Cardiology

eISSN 2975-2728

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Editor-in-Chief: Andrew J.S. Coats, Australia

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  • Familial hypercholesterolemia: state-of-the-art

    Ahmed Kamal Siddiqi, Kumail Mustafa Ali, Rameen Shahid, Shamna Haris, Anandita Kulkarni, Iliyan Mithani, Wilhelm Haverkamp, Muhammad Shahzeb Khan
    2026-06-29
    https://doi.org/10.4081/cardio.2026.102
    1494
    PDF: 623
    HTML: 43
  • The impact of maternal congenital heart disease on pregnancy outcomes in Malta: a retrospective study

    Maryanne Caruana, Miriam Gatt, Oscar Aquilina, Charles Savona Ventura, Victor Grech, Jane Somerville
    2023-12-29
    https://doi.org/10.4081/cardio.2023.14
    1835
    pdf: 253
    HTML: 2
  • The scientific targets: the myocardium, the vasculature and the body’s response to heart failure

    Rafael Vidal-Pérez, Ewa A. Jankowska
    2024-03-28
    https://doi.org/10.4081/cardio.2024.19
    2956
    PDF: 375
    HTML: 29
  • Modulation of cardiac metabolism in heart failure

    Giuseppe M.C. Rosano, Andrew J.S. Coats
    2024-11-05
    https://doi.org/10.4081/cardio.2024.30
    2626
    PDF: 1316
    HTML: 92
  • Metabolic dysfunction-associated steatotic liver disease and cardiovascular disease: a state-of-the-art review

    Aimen Shafiq, Ahmed Mustafa Rashid, Syed Raza Shah, Nicholas W.S. Chew, Wilhelm Haverkamp
    2026-04-10
    https://doi.org/10.4081/cardio.2026.94
    3867
    PDF: 1512
    HTML: 288
  • Intervention options: depression and cardiovascular disease during COVID-19

    Eirini Flouda, Athena Stefanatou, Tinia Apergi
    2023-11-28
    https://doi.org/10.4081/cardio.2023.5
    2061
    pdf: 429
    HTML: 42
  • Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

    Christian Basile, Stefan D. Anker, Gianluigi Savarese
    2025-06-30
    https://doi.org/10.4081/cardio.2025.73
    1112
    PDF: 403
    Supplementary: 237
    Appendix: 168
    HTML: 141
  • Bridging the gap between study outcomes and real-world results. Algorithm-driven management in a rural cardioMEMS population

    Marc Atzenhoefer, Elizabeth Dille, Rebecca Steinke, Nicole Weigert, Keri Sabel, Kirsten Rasmussen
    2025-04-16
    https://doi.org/10.4081/cardio.2025.63
    3912
    PDF: 894
    HTML: 70
  • Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

    Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker
    2024-06-28
    https://doi.org/10.4081/cardio.2024.40
    5967
    PDF: 956
    HTML: 57
  • Lipoprotein(a): what clinicians need to know

    Laibah Arshad Khan, Muhammad Hanif, Ahmed Mustafa Rashid
    2025-09-01
    https://doi.org/10.4081/cardio.2025.80
    1447
    PDF: 1436
    HTML: 38
  • Filling the void: digoxin and the first randomized evidence in rheumatic heart disease

    Viana Copeland, Andrew J.S. Coats, Javed Butler, Stefan D. Anker
    2026-07-03
    https://doi.org/10.4081/cardio.2026.108
    163
    PDF: 63
    HTML: 9
  • Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

    Christian Basile, Stefan D. Anker, Gianluigi Savarese
    2025-07-16
    https://doi.org/10.4081/cardio.2025.76
    1013
    PDF: 325
    Supplementary: 221
    Appendix: 219
    HTML: 69
  • iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

    Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano
    2025-09-30
    https://doi.org/10.4081/cardio.2025.86
    4141
    PDF: 3626
    Supplementary: 432
    Appendix: 376
  • The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

    Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus
    2025-06-30
    https://doi.org/10.4081/cardio.2025.67
    3137
    PDF: 647
    HTML: 155
  • Cardiac wasting in patients with advanced cancer: state of the art review

    Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker
    2025-04-16
    https://doi.org/10.4081/cardio.2025.65
    2987
    PDF: 791
    HTML: 77
  • The impact of diurnal fasting during Ramadan on patients with established cardiac disease: a systematic review

    Marwan M. Refaat, Nadim El Jamal, Hebah M. El-Rayess, Anthony Gebran, Amar M. Salam
    2024-06-28
    https://doi.org/10.4081/cardio.2024.32
    3485
    PDF: 1303
    HTML: 86
  • Treatment pathways in patients with heart failure with preserved ejection fraction and obesity: perspectives from cardiology specialists and patients

    Javed Butler, Sanjiv J. Shah, Melissa Magwire, Carlos Campos, Muhammad Shariq Usman, Anthony Hoovler, Anup Sabharwal, Barry A. Borlaug
    2024-06-28
    https://doi.org/10.4081/cardio.2024.38
    2497
    PDF: 1056
    SUPPLEMENTARY MATERIAL: 381
    GRAPHICAL ABSTRACT: 318
    HTML: 212
  • Evolving targets for heart failure: the journey so far

    Giuseppe M.C. Rosano, Jerneja Farkas
    2023-11-28
    https://doi.org/10.4081/cardio.2023.6
    2412
    pdf: 506
    HTML: 4
  • Depression, health-related quality of life and life satisfaction in patients with heart failure

    Natasa Sedlar Kobe, Daniel Omersa, Mitja Lainscak, Jerneja Farkas
    2024-11-05
    https://doi.org/10.4081/cardio.2024.47
    3247
    PDF: 867
    HTML: 15
  • Effect of metformin and empagliflozin on myocardial function in insulin-resistant patients with heart failure: rationale and design of the METRIS-HF-DZHK18 Trial

    Wolfram Doehner, Tim Friede, Frank Edelmann, Ulf Landmesser, Sebastian Winkler, Burkert Pieske, Fabian Knebel, Sebastian Kelle, Diethelm Tschöpe, Antje Meyer, Nadja Jauert, Marius Placzek, Jeanette Schulz-Menger, Stephan von Haehling, Stefan D. Anker
    2025-12-31
    https://doi.org/10.4081/cardio.2025.89
    498
    PDF: 215
    Appendix: 73
    HTML: 18
  • Quality of life in Maltese adults with congenital heart disease: a second look An APPROACH-IS substudy

    Maryanne Caruana, Philip Moons, Adrienne H. Kovacs, Koen Luyckx, Corina Thomet, Werner Budts, Maayke Sluman, Katrine Eriksen, Mikael Dellborg, Malin Berghammer, Bengt Johansson, Alexandra Soufi, Edward Callus, Victor Grech, Silke Apers
    2024-03-28
    https://doi.org/10.4081/cardio.2024.26
    2012
    PDF: 261
    HTML: 9
  • Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

    Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker
    2023-12-27
    https://doi.org/10.4081/cardio.2023.15
    2966
    pdf: 875
    HTML: 59
  • Aldosterone synthase inhibitors in cardio-renal diseases: a state-of-the-art review

    Muhammad Hamza Dawood, Muhammad Shahzeb Khan, Ahmed Mustafa Rashid, Wilhelm Haverkamp
    2025-12-31
    https://doi.org/10.4081/cardio.2025.91
    1000
    PDF: 547
    HTML: 87
  • Adherence to lifestyle therapy in patients with chronic heart failure and comorbidity

    Elena Efremova, Alexander Shutov
    2023-12-20
    https://doi.org/10.4081/cardio.2023.8
    1466
    pdf: 469
    HTML: 48
  • Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

    Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf
    2025-08-20
    https://doi.org/10.4081/cardio.2025.78
    767
    PDF: 539
    Appendix: 285
    HTML: 75
  • Defining iron replete status in patients with heart failure treated with intravenous iron

    Khawaja M. Talha, Javed Butler, Stephan von Haehling, Mitja Lainscak, Piotr Ponikowski, Stefan D. Anker
    2023-12-21
    https://doi.org/10.4081/cardio.2023.17
    3384
    pdf: 549
    HTML: 81
  • Is the obesity paradox present in left ventricular assist device recipients? A BMI-based analysis

    Saad Ahmed Waqas, Hibah Siddiqui, Faouzi Kallel, Shahzad Hassan
    2025-09-30
    https://doi.org/10.4081/cardio.2025.84
    418
    PDF: 451
    Supplementary: 215
    HTML: 62
  • Detection of early heart failure with preserved ejection fraction in metabolic syndrome patients detected as part of a national screening program in middle aged subjects

    Jelena Čelutkienė, Agnė Monika Jakštaitė, Jolita Badarienė, Svetlana Solovjova, Ieva Slivovskaja, Rokas Navickas, Edita Kazėnaitė, Egidija Rinkūnienė, Alma Čypienė, Jonas Misiūra, Ligita Ryliškytė, Aleksandras Laucevičius, Andrew J.S. Coats
    2023-12-29
    https://doi.org/10.4081/cardio.2023.3
    1820
    pdf: 408
    HTML: 15
  • The association of iron deficiency with right ventricular dysfunction in Africans with heart failure

    Adeseye A. Akintunde, Sope T. Orugun
    2024-12-30
    https://doi.org/10.4081/cardio.2024.53
    2805
    PDF: 476
    Appendix B: 523
    Appendix A: 372
    HTML: 13
  • Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

    Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek
    2024-06-28
    https://doi.org/10.4081/cardio.2024.39
    1917
    PDF: 639
    HTML: 23
  • Iron supplementation in heart failure and iron deficiency: does it help?

    Laibah Arshad Khan, Syed Sarmad Javaid, Javed Butler
    2025-09-30
    https://doi.org/10.4081/cardio.2025.82
    1026
    PDF: 579
    HTML: 100
  • Prognostic factors and outcome in patients submitted into coronary artery bypass surgery with total arterial myocardial revascularization

    Elias Tassoulas, Dimitrios Tasoulas, Christos Papaconstantinou, Ioannis Chlorogiannis
    2024-12-30
    https://doi.org/10.4081/cardio.2024.46
    3097
    PDF: 582
    HTML: 47
  • Epidemiology of peripartum cardiomyopathy in Africa

    Kamilu M. Karaye, Abdulrazaq G. Habib, Karen Sliwa
    2024-06-28
    https://doi.org/10.4081/cardio.2024.31
    2848
    PDF: 623
    HTML: 177
  • Advanced cancer as a heart failure like syndrome due to cardiac wasting cardiomyopathy: facts and numbers

    Muhammad Shahzeb Khan, Javed Butler, Laibah Arshad Khan, Markus S. Anker
    2024-12-30
    https://doi.org/10.4081/cardio.2024.58
    3678
    PDF: 739
    HTML: 127
  • Mineralocorticoid receptor antagonists in heart failure with preserved (and mildly reduced) ejection fraction: a comparative review of spironolactone and finerenone

    Hafsa Azam, Syed Sarmad Javaid, Mahir Karakas
    2026-07-06
    https://doi.org/10.4081/cardio.2026.110
    112
    PDF: 65
    HTML: 6
  • Obesity and left atrial function: state of the art

    Ahmed Mustafa Rashid, Muhammad Shahzeb Khan, Fawaz Alenezi, Stefan D. Anker, Fabian Knebel
    2026-03-31
    https://doi.org/10.4081/cardio.2026.96
    979
    PDF: 348
    HTML: 128
  • Beyond trial neutrality: treatment discontinuation and the hidden signal in SPIRIT-HF trial

    Viana Copeland, Andrew J.S. Coats
    2026-03-31
    https://doi.org/10.4081/cardio.2026.100
    1420
    PDF: 401
    HTML: 210
  • Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes

    Asad Gul Rao, Syed Sarmad Javaid, Ahmed Mustafa Rashid, Fawaz Alenezi
    2025-09-15
    https://doi.org/10.4081/cardio.2025.81
    1451
    PDF: 708
    HTML: 296
  • The muscle hypothesis of shortness of breath in patients with cachexia

    Stefan D. Anker, Muhammad Shahzeb Khan, Laibah Arshad Khan, Giuseppe M.C. Rosano, Maurizio Volterrani, Mitja Lainscak, Piotr Ponikowski, Andrew J.S. Coats
    2024-12-30
    https://doi.org/10.4081/cardio.2024.57
    3665
    PDF: 1014
    HTML: 56
  • Biological plausibility and implications of obesity associated valvular heart diseases

    Francesco Fioretti, Brian R. Lindman, Javed Butler
    2024-11-05
    https://doi.org/10.4081/cardio.2024.49
    3004
    PDF: 939
    HTML: 40
  • Demographic and regional trends of heart failure and cachexia-related mortality among older adults in the United States, from 1999 to 2020

    Ishaque Hameed, Muhammad Nashit, Zahra Quettawala Mufaddal, Syed Sarmad Javaid, Muhammad Hanif
    2025-09-19
    https://doi.org/10.4081/cardio.2025.83
    602
    PDF: 371
    HTML: 83
  • Hypertension-related heart failure mortality among older adults in the United States: a nationwide analysis of demographic and regional trends

    Muhammad Muneeb Ur Rehman, Muhammad Sameer Arshad, Muhammad Abdul Tawab, Rahael Javaid, Sunil Modi, Marat Fudim
    2026-03-31
    https://doi.org/10.4081/cardio.2026.97
    1376
    PDF: 366
    SUPPLEMENTARY FILES: 258
    HTML: 141
  • The effect of SGLT2 inhibitors on health status in patients with heart failure: a systematic review and meta-analysis

    Muhammad Shariq Usman, Arsalan Hamid, Shurjeel Uddin Qazi, Mikhail N. Kosiborod, Deepak L. Bhatt, Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler
    2024-06-28
    https://doi.org/10.4081/cardio.2024.35
    3707
    PDF: 865
    Conflict of interest: 375
    SUPPLEMENTARY MATERIAL: 330
    HTML: 115
  • Evaluating serum galectin-3 binding protein as a diagnostic and prognostic biomarker in pulmonary arterial hypertension: a comparative study

    Arif Albulushi, Lama S. Alfehaid, Mosaad Alhussein, Amr Youssef
    2024-12-30
    https://doi.org/10.4081/cardio.2024.50
    2045
    PDF: 687
    HTML: 29
  • The impact of frailty on in-hospital outcomes in patients with HFrEF

    Saad Ahmed Waqas, Taimor Mohammed Khan, Ahmed Kamal Siddiqi, Shahzad Hassan, Stefan D. Anker
    2025-12-17
    https://doi.org/10.4081/cardio.2025.88
    670
    PDF: 277
    Supplementary: 112
    HTML: 27
  • Rationale and design for the peripartum cardiomyopathy in Nigeria (PEACE) registry

    Kamilu M. Karaye, Idris Y. Mohammed, Okechukwu S. Ogah, Basil N. Okeahialam
    2023-11-28
    https://doi.org/10.4081/cardio.2023.4
    1225
    pdf: 384
    HTML: 70
  • Importance of patient-reported outcomes in cardiovascular illnesses

    Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan
    2025-06-30
    https://doi.org/10.4081/cardio.2025.69
    2465
    PDF: 614
    HTML: 193
  • COVID-19 myocarditis

    Reinaldo B. Bestetti, Rosemary Furlan-Daniel, Luciano P. Pereira
    2024-03-28
    https://doi.org/10.4081/cardio.2024.21
    3225
    PDF: 438
    HTML: 14
  • Frequency of low-density-lipoprotein-cholesterol measurement and risk of major adverse cardiovascular outcomes: a 5-million-person nationwide cohort study

    Denis M. Ngina, Wolfram Doehner, George Ntaios, Yvonne Nartey, Ralph K. Akyea
    2025-09-30
    https://doi.org/10.4081/cardio.2025.85
    716
    PDF: 129
    HTML: 77
  • Applicability of obesity clinical practice guidelines in low- and middle-income countries

    Shelley Zieroth, Fausto Pinto, Stefan D. Anker, William T. Abraham, John J. Atherton, Javed Butler, Vijay Chopra, Andrew J.S. Coats, Martha Gulati, Tammy L. Kindel, José Luis Zamorano, Yuhui Zhang, Linong Ji, Yann Colardelle, Richard B. Weiskopf
    2025-06-30
    https://doi.org/10.4081/cardio.2025.77
    1759
    PDF: 850
    Appendix: 313
    HTML: 53
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iCARDIO

May 1 marked the release of the #iCARDIO Guidelines on Heart Failure, now live in Global Cardiology. This global-first effort brings flexible, practical guidance to frontline providers managing #heartfailure in any setting. www.globalcardiology.info/site/article... #GlobalHealth #cardiosky

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— iCardio (@icardio.bsky.social) May 13, 2025 at 8:26

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