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Bridging the gap between study outcomes and real-world results. Algorithm-driven management in a rural cardioMEMS population

Marc Atzenhoefer, Elizabeth Dille, Rebecca Steinke, Nicole Weigert, Keri Sabel, Kirsten Rasmussen

2025-04-16

https://doi.org/10.4081/cardio.2025.63

3189

PDF: 649

HTML: 20
The scientific targets: the myocardium, the vasculature and the body’s response to heart failure

Rafael Vidal-Pérez, Ewa A. Jankowska

2024-03-28

https://doi.org/10.4081/cardio.2024.19

2705

PDF: 236

HTML: 21
Modulation of cardiac metabolism in heart failure

Giuseppe M.C. Rosano, Andrew J.S. Coats

2024-11-05

https://doi.org/10.4081/cardio.2024.30

2372

PDF: 1162

HTML: 30
Treatment pathways in patients with heart failure with preserved ejection fraction and obesity: perspectives from cardiology specialists and patients

Javed Butler, Sanjiv J. Shah, Melissa Magwire, Carlos Campos, Muhammad Shariq Usman, Anthony Hoovler, Anup Sabharwal, Barry A. Borlaug

2024-06-28

https://doi.org/10.4081/cardio.2024.38

1986

PDF: 527

SUPPLEMENTARY MATERIAL: 301

GRAPHICAL ABSTRACT: 265

HTML: 31
Evolving targets for heart failure: the journey so far

Giuseppe M.C. Rosano, Jerneja Farkas

2023-11-28

https://doi.org/10.4081/cardio.2023.6

2071

pdf: 337

HTML: 4
Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

Christian Basile, Stefan D. Anker, Gianluigi Savarese

2025-06-30

https://doi.org/10.4081/cardio.2025.73

798

PDF: 226

Supplementary: 145

Appendix: 112

HTML: 47
The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus

2025-06-30

https://doi.org/10.4081/cardio.2025.67

2212

PDF: 478

HTML: 113
Clinical trial design, endpoints and regulatory considerations in heart failure

Giuseppe M.C. Rosano

2024-03-28

https://doi.org/10.4081/cardio.2024.18

5696

PDF: 469

HTML: 69
Effect of metformin and empagliflozin on myocardial function in insulin-resistant patients with heart failure: rationale and design of the METRIS-HF-DZHK18 Trial

Wolfram Doehner, Tim Friede, Frank Edelmann, Ulf Landmesser, Sebastian Winkler, Burkert Pieske, Fabian Knebel, Sebastian Kelle, Diethelm Tschöpe, Antje Meyer, Nadja Jauert, Marius Placzek, Jeanette Schulz-Menger, Stephan von Haehling, Stefan D. Anker

2025-12-31

https://doi.org/10.4081/cardio.2025.89

140

PDF: 44

Appendix: 18

HTML: 0
Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

Christian Basile, Stefan D. Anker, Gianluigi Savarese

2025-07-16

https://doi.org/10.4081/cardio.2025.76

807

PDF: 198

Supplementary: 151

Appendix: 106

HTML: 39
Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker

2024-06-28

https://doi.org/10.4081/cardio.2024.40

5404

PDF: 743

HTML: 30
Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker

2023-12-27

https://doi.org/10.4081/cardio.2023.15

2572

pdf: 588

HTML: 31
Cardiac wasting in patients with advanced cancer: state of the art review

Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker

2025-04-16

https://doi.org/10.4081/cardio.2025.65

2466

PDF: 511

HTML: 42
Iron supplementation in heart failure and iron deficiency: does it help?

Laibah Arshad Khan, Syed Sarmad Javaid, Javed Butler

2025-09-30

https://doi.org/10.4081/cardio.2025.82

289

PDF: 315

HTML: 55
Adherence to lifestyle therapy in patients with chronic heart failure and comorbidity

Elena Efremova, Alexander Shutov

2023-12-20

https://doi.org/10.4081/cardio.2023.8

1249

pdf: 278

HTML: 30
Depression, health-related quality of life and life satisfaction in patients with heart failure

Natasa Sedlar Kobe, Daniel Omersa, Mitja Lainscak, Jerneja Farkas

2024-11-05

https://doi.org/10.4081/cardio.2024.47

2864

PDF: 702

HTML: 2
The association of iron deficiency with right ventricular dysfunction in Africans with heart failure

Adeseye A. Akintunde, Sope T. Orugun

2024-12-30

https://doi.org/10.4081/cardio.2024.53

2364

PDF: 402

Appendix B: 438

Appendix A: 323

HTML: 2
Defining iron replete status in patients with heart failure treated with intravenous iron

Khawaja M. Talha, Javed Butler, Stephan von Haehling, Mitja Lainscak, Piotr Ponikowski, Stefan D. Anker

2023-12-21

https://doi.org/10.4081/cardio.2023.17

3013

pdf: 331

HTML: 56
Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek

2024-06-28

https://doi.org/10.4081/cardio.2024.39

1561

PDF: 474

HTML: 4
Detection of early heart failure with preserved ejection fraction in metabolic syndrome patients detected as part of a national screening program in middle aged subjects

Jelena Čelutkienė, Agnė Monika Jakštaitė, Jolita Badarienė, Svetlana Solovjova, Ieva Slivovskaja, Rokas Navickas, Edita Kazėnaitė, Egidija Rinkūnienė, Alma Čypienė, Jonas Misiūra, Ligita Ryliškytė, Aleksandras Laucevičius, Andrew J.S. Coats

2023-12-29

https://doi.org/10.4081/cardio.2023.3

1595

pdf: 244

HTML: 5
Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf

2025-08-20

https://doi.org/10.4081/cardio.2025.78

403

PDF: 359

Appendix: 216

HTML: 52
The effect of SGLT2 inhibitors on health status in patients with heart failure: a systematic review and meta-analysis

Muhammad Shariq Usman, Arsalan Hamid, Shurjeel Uddin Qazi, Mikhail N. Kosiborod, Deepak L. Bhatt, Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler

2024-06-28

https://doi.org/10.4081/cardio.2024.35

2581

PDF: 670

Conflict of interest: 322

SUPPLEMENTARY MATERIAL: 260

HTML: 64
Advanced cancer as a heart failure like syndrome due to cardiac wasting cardiomyopathy: facts and numbers

Muhammad Shahzeb Khan, Javed Butler, Laibah Arshad Khan, Markus S. Anker

2024-12-30

https://doi.org/10.4081/cardio.2024.58

3141

PDF: 551

HTML: 69
Demographic and regional trends of heart failure and cachexia-related mortality among older adults in the United States, from 1999 to 2020

Ishaque Hameed, Muhammad Nashit, Zahra Quettawala Mufaddal, Syed Sarmad Javaid, Muhammad Hanif

2025-09-19

https://doi.org/10.4081/cardio.2025.83

240

PDF: 208

HTML: 33
iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano

2025-09-30

https://doi.org/10.4081/cardio.2025.86

1336

PDF: 2548

Supplementary: 321

Appendix: 267
The impact of maternal congenital heart disease on pregnancy outcomes in Malta: a retrospective study

Maryanne Caruana, Miriam Gatt, Oscar Aquilina, Charles Savona Ventura, Victor Grech, Jane Somerville

2023-12-29

https://doi.org/10.4081/cardio.2023.14

1565

pdf: 142

HTML: 2
Lipoprotein(a): what clinicians need to know

Laibah Arshad Khan, Muhammad Hanif, Ahmed Mustafa Rashid

2025-09-01

https://doi.org/10.4081/cardio.2025.80

393

PDF: 749

HTML: 24
Using multiple primary endpoints in clinical trials with a focus on heart failure

Stefan D. Anker, Javed Butler, Khawaja M. Talha, Tim Friede

2024-06-28

https://doi.org/10.4081/cardio.2024.33

5611

PDF: 745

HTML: 223
The impact of frailty on in-hospital outcomes in patients with HFrEF

Saad Ahmed Waqas, Taimor Mohammed Khan, Ahmed Kamal Siddiqi, Shahzad Hassan, Stefan D. Anker

2025-12-17

https://doi.org/10.4081/cardio.2025.88

202

PDF: 70

Supplementary: 12

HTML: 5
Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes

Asad Gul Rao, Syed Sarmad Javaid, Ahmed Mustafa Rashid, Fawaz Alenezi

2025-09-15

https://doi.org/10.4081/cardio.2025.81

402

PDF: 378

HTML: 154
Is the obesity paradox present in left ventricular assist device recipients? A BMI-based analysis

Saad Ahmed Waqas, Hibah Siddiqui, Faouzi Kallel, Shahzad Hassan

2025-09-30

https://doi.org/10.4081/cardio.2025.84

198

PDF: 243

Supplementary: 151

HTML: 23
Epidemiology of peripartum cardiomyopathy in Africa

Kamilu M. Karaye, Abdulrazaq G. Habib, Karen Sliwa

2024-06-28

https://doi.org/10.4081/cardio.2024.31

2320

PDF: 517

HTML: 102
Quality of life in Maltese adults with congenital heart disease: a second look An APPROACH-IS substudy

Maryanne Caruana, Philip Moons, Adrienne H. Kovacs, Koen Luyckx, Corina Thomet, Werner Budts, Maayke Sluman, Katrine Eriksen, Mikael Dellborg, Malin Berghammer, Bengt Johansson, Alexandra Soufi, Edward Callus, Victor Grech, Silke Apers

2024-03-28

https://doi.org/10.4081/cardio.2024.26

1673

PDF: 168

HTML: 9
Intervention options: depression and cardiovascular disease during COVID-19

Eirini Flouda, Athena Stefanatou, Tinia Apergi

2023-11-28

https://doi.org/10.4081/cardio.2023.5

1830

pdf: 258

HTML: 21
Preliminary study on the immunohistochemical expression of galectin-3 in hypertrophic hearts

Cecilia Salzillo, Lorenzo Giovannico, Giuseppe Fischetti, Gerardo Cazzato, Mario Magistro, Grazia Nucci, Gabriella Serio, Andrea Marzullo

2024-06-28

https://doi.org/10.4081/cardio.2024.37

1354

PDF: 334

HTML: 12
Importance of patient-reported outcomes in cardiovascular illnesses

Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan

2025-06-30

https://doi.org/10.4081/cardio.2025.69

2009

PDF: 435

HTML: 110
Aldosterone synthase inhibitors in cardio-renal diseases: a state-of-the-art review

Muhammad Hamza Dawood, Muhammad Shahzeb Khan, Ahmed Mustafa Rashid, Wilhelm Haverkamp

2025-12-31

https://doi.org/10.4081/cardio.2025.91

161

PDF: 56

HTML: 2
iCARDIO Alliance Global Implementation Guidelines on Heart Failure 2025

Vijay Chopra, Muhammad Shahzeb Khan, Magdy Abdelhamid, William T. Abraham, Offer Amir, Stefan D. Anker, John J. Atherton, Fernando Bacal, Ralph Stephan von Bardeleben, Dulce Brito, Lucrecia Maria Burgos, Javed Butler, Maria Rosa Costanzo, Albertino Damasceno, Justin A. Ezekowitz, Ishaque Hameed, Sivadasanpillai Harikrishnan, Tiny Jaarsma, Anuradha Lala, Ileana L. Piña, Clara Saldarriaga, David Sim, John R. Teerlink, Nqoba Tsabedze, Hiroyuki Tsutsui, Jing Yu, Yuhui Zhang, Mohammad Zubaid, Nikhil Balankhe, Juan Esteban Gomez-Mesa, James L. Januzzi, Marvin Konstam, Rhonda Monroe, Elijah Ogola, Vinayagam Palaniappan, Mark C. Petrie, Fausto J. Pinto, Girish C. Rajadhyaksha, Amina Rakisheva, Carlos E. Ramos, Victor Rossel, Naoki Sato, P. Christian Schulze, Andrew Sindone, Hadi N. Skouri, Harriette G.C. Van Spall, Aistė Štaraitė, Lynne Warner Stevenson, Kadhim Sulaiman, Tzung-Dau Wang, Michael Böhm, Andrew J.S. Coats, Shelley Zieroth

2025-06-30

https://doi.org/10.4081/cardio.2025.70

12266

PDF: 8003

Appendix: 1051
The muscle hypothesis of shortness of breath in patients with cachexia

Stefan D. Anker, Muhammad Shahzeb Khan, Laibah Arshad Khan, Giuseppe M.C. Rosano, Maurizio Volterrani, Mitja Lainscak, Piotr Ponikowski, Andrew J.S. Coats

2024-12-30

https://doi.org/10.4081/cardio.2024.57

2559

PDF: 732

HTML: 13
Biological plausibility and implications of obesity associated valvular heart diseases

Francesco Fioretti, Brian R. Lindman, Javed Butler

2024-11-05

https://doi.org/10.4081/cardio.2024.49

2562

PDF: 673

HTML: 4
SGLT2 inhibitors and risk reduction for mortality in high-risk patients: a meta-analysis of randomized controlled trials

Tariq Jamal Siddiqi, Javed Butler, Andrew J.S. Coats, Subodh Verma, Tim Friede, Gerasimos Filippatos, Stefan D. Anker

2023-11-23

https://doi.org/10.4081/cardio.2023.2

1161

pdf: 260

Supplementary Material: 41

HTML: 129
Relaxin-2 for heart failure with preserved ejection fraction: a comment on the termination of a phase-II trial investigating the relaxin-2 analogue, LY3540378

Thomas Bernd Dschietzig, Guy Salama

2024-12-30

https://doi.org/10.4081/cardio.2024.56

4054

PDF: 926

HTML: 88
To clip or not to clip moderate-to-severe functional mitral regurgitation in patients with heart failure?

Muhammad Shahzeb Khan, Javed Butler, Tim Friede, Piotr Ponikowski, Stefan D. Anker

2024-11-05

https://doi.org/10.4081/cardio.2024.44

3021

PDF: 780

HTML: 20
Clinical profiles and short-term outcomes of women with peripartum and dilated cardiomyopathies

Babalawan Muhammad, Naser A. Ishaq, Kamilu M. Karaye

2024-11-05

https://doi.org/10.4081/cardio.2024.42

2122

PDF: 585

HTML: 3
The impact of diurnal fasting during Ramadan on patients with established cardiac disease: a systematic review

Marwan M. Refaat, Nadim El Jamal, Hebah M. El-Rayess, Anthony Gebran, Amar M. Salam

2024-06-28

https://doi.org/10.4081/cardio.2024.32

2507

PDF: 891

HTML: 16
COVID-19 myocarditis

Reinaldo B. Bestetti, Rosemary Furlan-Daniel, Luciano P. Pereira

2024-03-28

https://doi.org/10.4081/cardio.2024.21

2710

PDF: 251

HTML: 14
Rationale and design for the peripartum cardiomyopathy in Nigeria (PEACE) registry

Kamilu M. Karaye, Idris Y. Mohammed, Okechukwu S. Ogah, Basil N. Okeahialam

2023-11-28

https://doi.org/10.4081/cardio.2023.4

1033

pdf: 241

HTML: 51
The Global Implementation Guidelines Initiative: how to optimize cardio-renal-metabolic care worldwide

Fausto J. Pinto, Stefan D. Anker, William T. Abraham, John J. Atherton, Javed Butler, Vijay Chopra, Andrew J.S. Coats, Yann Colardelle, Maria Rosa Costanzo, Veronica Dean, Gerasimos Filippatos, Martha Gulati, Julio Rosenstock, John Teerlink, Subodh Verma, Jose Luis Zamorano, Yuhui Zhang, Shelley Zieroth

2025-04-16

https://doi.org/10.4081/cardio.2025.68

3421

PDF: 548

Appendix: 397

HTML: 27
Aortic valve replacement in asymptomatic severe aortic stenosis. A focused review

Aimen Shafiq, Rohan Dev Trehan, Mitja Lainscak, Sanjeev Trehan

2025-12-31

https://doi.org/10.4081/cardio.2025.93

125

PDF: 39

HTML: 0
Applicability of obesity clinical practice guidelines in low- and middle-income countries

Shelley Zieroth, Fausto Pinto, Stefan D. Anker, William T. Abraham, John J. Atherton, Javed Butler, Vijay Chopra, Andrew J.S. Coats, Martha Gulati, Tammy L. Kindel, José Luis Zamorano, Yuhui Zhang, Linong Ji, Yann Colardelle, Richard B. Weiskopf

2025-06-30

https://doi.org/10.4081/cardio.2025.77

1220

PDF: 610

Appendix: 237

HTML: 23

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