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• Bridging the gap between study outcomes and real-world results. Algorithm-driven management in a rural cardioMEMS population

  Marc Atzenhoefer, Elizabeth Dille, Rebecca Steinke, Nicole Weigert, Keri Sabel, Kirsten Rasmussen

  2025-04-16

  https://doi.org/10.4081/cardio.2025.63

  3599

  PDF: 780

  HTML: 49

• The scientific targets: the myocardium, the vasculature and the body’s response to heart failure

  Rafael Vidal-Pérez, Ewa A. Jankowska

  2024-03-28

  https://doi.org/10.4081/cardio.2024.19

  2819

  PDF: 286

  HTML: 25

• Modulation of cardiac metabolism in heart failure

  Giuseppe M.C. Rosano, Andrew J.S. Coats

  2024-11-05

  https://doi.org/10.4081/cardio.2024.30

  2486

  PDF: 1220

  HTML: 64

• Treatment pathways in patients with heart failure with preserved ejection fraction and obesity: perspectives from cardiology specialists and patients

  Javed Butler, Sanjiv J. Shah, Melissa Magwire, Carlos Campos, Muhammad Shariq Usman, Anthony Hoovler, Anup Sabharwal, Barry A. Borlaug

  2024-06-28

  https://doi.org/10.4081/cardio.2024.38

  2175

  PDF: 593

  SUPPLEMENTARY MATERIAL: 330

  GRAPHICAL ABSTRACT: 283

  HTML: 48

• Evolving targets for heart failure: the journey so far

  Giuseppe M.C. Rosano, Jerneja Farkas

  2023-11-28

  https://doi.org/10.4081/cardio.2023.6

  2185

  pdf: 399

  HTML: 4

• Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-06-30

  https://doi.org/10.4081/cardio.2025.73

  931

  PDF: 302

  Supplementary: 178

  Appendix: 133

  HTML: 84
• 

  The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

  Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus

  2025-06-30

  https://doi.org/10.4081/cardio.2025.67

  2677

  PDF: 546

  HTML: 138

• Clinical trial design, endpoints and regulatory considerations in heart failure

  Giuseppe M.C. Rosano

  2024-03-28

  https://doi.org/10.4081/cardio.2024.18

  5844

  PDF: 529

  HTML: 69

• Effect of metformin and empagliflozin on myocardial function in insulin-resistant patients with heart failure: rationale and design of the METRIS-HF-DZHK18 Trial

  Wolfram Doehner, Tim Friede, Frank Edelmann, Ulf Landmesser, Sebastian Winkler, Burkert Pieske, Fabian Knebel, Sebastian Kelle, Diethelm Tschöpe, Antje Meyer, Nadja Jauert, Marius Placzek, Jeanette Schulz-Menger, Stephan von Haehling, Stefan D. Anker

  2025-12-31

  https://doi.org/10.4081/cardio.2025.89

  311

  PDF: 109

  Appendix: 33

  HTML: 11

• Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-07-16

  https://doi.org/10.4081/cardio.2025.76

  907

  PDF: 257

  Supplementary: 185

  Appendix: 131

  HTML: 59

• Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

  Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker

  2024-06-28

  https://doi.org/10.4081/cardio.2024.40

  5650

  PDF: 847

  HTML: 47

• Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

  Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker

  2023-12-27

  https://doi.org/10.4081/cardio.2023.15

  2762

  pdf: 739

  HTML: 47

• Cardiac wasting in patients with advanced cancer: state of the art review

  Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker

  2025-04-16

  https://doi.org/10.4081/cardio.2025.65

  2783

  PDF: 645

  HTML: 65

• Iron supplementation in heart failure and iron deficiency: does it help?

  Laibah Arshad Khan, Syed Sarmad Javaid, Javed Butler

  2025-09-30

  https://doi.org/10.4081/cardio.2025.82

  701

  PDF: 437

  HTML: 72

• Adherence to lifestyle therapy in patients with chronic heart failure and comorbidity

  Elena Efremova, Alexander Shutov

  2023-12-20

  https://doi.org/10.4081/cardio.2023.8

  1358

  pdf: 347

  HTML: 43

• Depression, health-related quality of life and life satisfaction in patients with heart failure

  Natasa Sedlar Kobe, Daniel Omersa, Mitja Lainscak, Jerneja Farkas

  2024-11-05

  https://doi.org/10.4081/cardio.2024.47

  3027

  PDF: 787

  HTML: 6

• The association of iron deficiency with right ventricular dysfunction in Africans with heart failure

  Adeseye A. Akintunde, Sope T. Orugun

  2024-12-30

  https://doi.org/10.4081/cardio.2024.53

  2544

  PDF: 429

  Appendix B: 474

  Appendix A: 338

  HTML: 7

• Defining iron replete status in patients with heart failure treated with intravenous iron

  Khawaja M. Talha, Javed Butler, Stephan von Haehling, Mitja Lainscak, Piotr Ponikowski, Stefan D. Anker

  2023-12-21

  https://doi.org/10.4081/cardio.2023.17

  3267

  pdf: 419

  HTML: 65

• Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

  Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek

  2024-06-28

  https://doi.org/10.4081/cardio.2024.39

  1719

  PDF: 538

  HTML: 10

• Detection of early heart failure with preserved ejection fraction in metabolic syndrome patients detected as part of a national screening program in middle aged subjects

  Jelena Čelutkienė, Agnė Monika Jakštaitė, Jolita Badarienė, Svetlana Solovjova, Ieva Slivovskaja, Rokas Navickas, Edita Kazėnaitė, Egidija Rinkūnienė, Alma Čypienė, Jonas Misiūra, Ligita Ryliškytė, Aleksandras Laucevičius, Andrew J.S. Coats

  2023-12-29

  https://doi.org/10.4081/cardio.2023.3

  1697

  pdf: 322

  HTML: 13

• Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

  Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf

  2025-08-20

  https://doi.org/10.4081/cardio.2025.78

  544

  PDF: 448

  Appendix: 235

  HTML: 68

• The effect of SGLT2 inhibitors on health status in patients with heart failure: a systematic review and meta-analysis

  Muhammad Shariq Usman, Arsalan Hamid, Shurjeel Uddin Qazi, Mikhail N. Kosiborod, Deepak L. Bhatt, Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler

  2024-06-28

  https://doi.org/10.4081/cardio.2024.35

  2991

  PDF: 735

  Conflict of interest: 339

  SUPPLEMENTARY MATERIAL: 284

  HTML: 83

• Advanced cancer as a heart failure like syndrome due to cardiac wasting cardiomyopathy: facts and numbers

  Muhammad Shahzeb Khan, Javed Butler, Laibah Arshad Khan, Markus S. Anker

  2024-12-30

  https://doi.org/10.4081/cardio.2024.58

  3501

  PDF: 623

  HTML: 107

• Beyond trial neutrality: treatment discontinuation and the hidden signal in SPIRIT-HF trial

  Viana Copeland, Andrew J.S. Coats

  2026-03-31

  https://doi.org/10.4081/cardio.2026.100

  531

  PDF: 191

  HTML: 95

• Demographic and regional trends of heart failure and cachexia-related mortality among older adults in the United States, from 1999 to 2020

  Ishaque Hameed, Muhammad Nashit, Zahra Quettawala Mufaddal, Syed Sarmad Javaid, Muhammad Hanif

  2025-09-19

  https://doi.org/10.4081/cardio.2025.83

  438

  PDF: 270

  HTML: 61

• Hypertension-related heart failure mortality among older adults in the United States: a nationwide analysis of demographic and regional trends

  Muhammad Muneeb Ur Rehman, Muhammad Sameer Arshad, Muhammad Abdul Tawab, Rahael Javaid, Sunil Modi, Marat Fudim

  2026-03-31

  https://doi.org/10.4081/cardio.2026.97

  576

  PDF: 182

  SUPPLEMENTARY FILES: 129

  HTML: 78

• iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

  Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano

  2025-09-30

  https://doi.org/10.4081/cardio.2025.86

  2847

  PDF: 3116

  Supplementary: 376

  Appendix: 305

• The impact of maternal congenital heart disease on pregnancy outcomes in Malta: a retrospective study

  Maryanne Caruana, Miriam Gatt, Oscar Aquilina, Charles Savona Ventura, Victor Grech, Jane Somerville

  2023-12-29

  https://doi.org/10.4081/cardio.2023.14

  1710

  pdf: 177

  HTML: 2

• Lipoprotein(a): what clinicians need to know

  Laibah Arshad Khan, Muhammad Hanif, Ahmed Mustafa Rashid

  2025-09-01

  https://doi.org/10.4081/cardio.2025.80

  677

  PDF: 1072

  HTML: 33

• Using multiple primary endpoints in clinical trials with a focus on heart failure

  Stefan D. Anker, Javed Butler, Khawaja M. Talha, Tim Friede

  2024-06-28

  https://doi.org/10.4081/cardio.2024.33

  5956

  PDF: 826

  HTML: 304

• Obesity and left atrial function: state of the art

  Ahmed Mustafa Rashid, Muhammad Shahzeb Khan, Fawaz Alenezi, Stefan D. Anker, Fabian Knebel

  2026-03-31

  https://doi.org/10.4081/cardio.2026.96

  398

  PDF: 170

  HTML: 62

• The impact of frailty on in-hospital outcomes in patients with HFrEF

  Saad Ahmed Waqas, Taimor Mohammed Khan, Ahmed Kamal Siddiqi, Shahzad Hassan, Stefan D. Anker

  2025-12-17

  https://doi.org/10.4081/cardio.2025.88

  459

  PDF: 174

  Supplementary: 49

  HTML: 20

• Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes

  Asad Gul Rao, Syed Sarmad Javaid, Ahmed Mustafa Rashid, Fawaz Alenezi

  2025-09-15

  https://doi.org/10.4081/cardio.2025.81

  728

  PDF: 532

  HTML: 242

• Is the obesity paradox present in left ventricular assist device recipients? A BMI-based analysis

  Saad Ahmed Waqas, Hibah Siddiqui, Faouzi Kallel, Shahzad Hassan

  2025-09-30

  https://doi.org/10.4081/cardio.2025.84

  308

  PDF: 333

  Supplementary: 166

  HTML: 43

• Epidemiology of peripartum cardiomyopathy in Africa

  Kamilu M. Karaye, Abdulrazaq G. Habib, Karen Sliwa

  2024-06-28

  https://doi.org/10.4081/cardio.2024.31

  2564

  PDF: 558

  HTML: 137

• Quality of life in Maltese adults with congenital heart disease: a second look An APPROACH-IS substudy

  Maryanne Caruana, Philip Moons, Adrienne H. Kovacs, Koen Luyckx, Corina Thomet, Werner Budts, Maayke Sluman, Katrine Eriksen, Mikael Dellborg, Malin Berghammer, Bengt Johansson, Alexandra Soufi, Edward Callus, Victor Grech, Silke Apers

  2024-03-28

  https://doi.org/10.4081/cardio.2024.26

  1786

  PDF: 203

  HTML: 9

• Intervention options: depression and cardiovascular disease during COVID-19

  Eirini Flouda, Athena Stefanatou, Tinia Apergi

  2023-11-28

  https://doi.org/10.4081/cardio.2023.5

  1952

  pdf: 321

  HTML: 30

• Preliminary study on the immunohistochemical expression of galectin-3 in hypertrophic hearts

  Cecilia Salzillo, Lorenzo Giovannico, Giuseppe Fischetti, Gerardo Cazzato, Mario Magistro, Grazia Nucci, Gabriella Serio, Andrea Marzullo

  2024-06-28

  https://doi.org/10.4081/cardio.2024.37

  1420

  PDF: 381

  HTML: 25
• 

  Importance of patient-reported outcomes in cardiovascular illnesses

  Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan

  2025-06-30

  https://doi.org/10.4081/cardio.2025.69

  2292

  PDF: 501

  HTML: 136

• Aldosterone synthase inhibitors in cardio-renal diseases: a state-of-the-art review

  Muhammad Hamza Dawood, Muhammad Shahzeb Khan, Ahmed Mustafa Rashid, Wilhelm Haverkamp

  2025-12-31

  https://doi.org/10.4081/cardio.2025.91

  547

  PDF: 192

  HTML: 30

• iCARDIO Alliance Global Implementation Guidelines on Heart Failure 2025

  Vijay Chopra, Muhammad Shahzeb Khan, Magdy Abdelhamid, William T. Abraham, Offer Amir, Stefan D. Anker, John J. Atherton, Fernando Bacal, Ralph Stephan von Bardeleben, Dulce Brito, Lucrecia Maria Burgos, Javed Butler, Maria Rosa Costanzo, Albertino Damasceno, Justin A. Ezekowitz, Ishaque Hameed, Sivadasanpillai Harikrishnan, Tiny Jaarsma, Anuradha Lala, Ileana L. Piña, Clara Saldarriaga, David Sim, John R. Teerlink, Nqoba Tsabedze, Hiroyuki Tsutsui, Jing Yu, Yuhui Zhang, Mohammad Zubaid, Nikhil Balankhe, Juan Esteban Gomez-Mesa, James L. Januzzi, Marvin Konstam, Rhonda Monroe, Elijah Ogola, Vinayagam Palaniappan, Mark C. Petrie, Fausto J. Pinto, Girish C. Rajadhyaksha, Amina Rakisheva, Carlos E. Ramos, Victor Rossel, Naoki Sato, P. Christian Schulze, Andrew Sindone, Hadi N. Skouri, Harriette G.C. Van Spall, Aistė Štaraitė, Lynne Warner Stevenson, Kadhim Sulaiman, Tzung-Dau Wang, Michael Böhm, Andrew J.S. Coats, Shelley Zieroth

  2025-06-30

  https://doi.org/10.4081/cardio.2025.70

  13832

  PDF: 8579

  Appendix: 1106

• The muscle hypothesis of shortness of breath in patients with cachexia

  Stefan D. Anker, Muhammad Shahzeb Khan, Laibah Arshad Khan, Giuseppe M.C. Rosano, Maurizio Volterrani, Mitja Lainscak, Piotr Ponikowski, Andrew J.S. Coats

  2024-12-30

  https://doi.org/10.4081/cardio.2024.57

  3006

  PDF: 880

  HTML: 35

• Biological plausibility and implications of obesity associated valvular heart diseases

  Francesco Fioretti, Brian R. Lindman, Javed Butler

  2024-11-05

  https://doi.org/10.4081/cardio.2024.49

  2771

  PDF: 830

  HTML: 22

• SGLT2 inhibitors and risk reduction for mortality in high-risk patients: a meta-analysis of randomized controlled trials

  Tariq Jamal Siddiqi, Javed Butler, Andrew J.S. Coats, Subodh Verma, Tim Friede, Gerasimos Filippatos, Stefan D. Anker

  2023-11-23

  https://doi.org/10.4081/cardio.2023.2

  1372

  pdf: 314

  Supplementary Material: 57

  HTML: 175

• Relaxin-2 for heart failure with preserved ejection fraction: a comment on the termination of a phase-II trial investigating the relaxin-2 analogue, LY3540378

  Thomas Bernd Dschietzig, Guy Salama

  2024-12-30

  https://doi.org/10.4081/cardio.2024.56

  4541

  PDF: 972

  HTML: 113

• To clip or not to clip moderate-to-severe functional mitral regurgitation in patients with heart failure?

  Muhammad Shahzeb Khan, Javed Butler, Tim Friede, Piotr Ponikowski, Stefan D. Anker

  2024-11-05

  https://doi.org/10.4081/cardio.2024.44

  3094

  PDF: 836

  HTML: 34

• Clinical profiles and short-term outcomes of women with peripartum and dilated cardiomyopathies

  Babalawan Muhammad, Naser A. Ishaq, Kamilu M. Karaye

  2024-11-05

  https://doi.org/10.4081/cardio.2024.42

  2227

  PDF: 638

  HTML: 5

• The impact of diurnal fasting during Ramadan on patients with established cardiac disease: a systematic review

  Marwan M. Refaat, Nadim El Jamal, Hebah M. El-Rayess, Anthony Gebran, Amar M. Salam

  2024-06-28

  https://doi.org/10.4081/cardio.2024.32

  3033

  PDF: 1185

  HTML: 22

• COVID-19 myocarditis

  Reinaldo B. Bestetti, Rosemary Furlan-Daniel, Luciano P. Pereira

  2024-03-28

  https://doi.org/10.4081/cardio.2024.21

  2816

  PDF: 335

  HTML: 14

• Rationale and design for the peripartum cardiomyopathy in Nigeria (PEACE) registry

  Kamilu M. Karaye, Idris Y. Mohammed, Okechukwu S. Ogah, Basil N. Okeahialam

  2023-11-28

  https://doi.org/10.4081/cardio.2023.4

  1134

  pdf: 284

  HTML: 61