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Global Cardiology

eISSN 2975-2728

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Editor-in-Chief: Andrew J.S. Coats, Australia

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  • Prognostic factors and outcome in patients submitted into coronary artery bypass surgery with total arterial myocardial revascularization

    Elias Tassoulas, Dimitrios Tasoulas, Christos Papaconstantinou, Ioannis Chlorogiannis
    2024-12-30
    https://doi.org/10.4081/cardio.2024.46
    3036
    PDF: 534
    HTML: 36
  • Evaluating serum galectin-3 binding protein as a diagnostic and prognostic biomarker in pulmonary arterial hypertension: a comparative study

    Arif Albulushi, Lama S. Alfehaid, Mosaad Alhussein, Amr Youssef
    2024-12-30
    https://doi.org/10.4081/cardio.2024.50
    2009
    PDF: 629
    HTML: 23
  • Advanced cancer as a heart failure like syndrome due to cardiac wasting cardiomyopathy: facts and numbers

    Muhammad Shahzeb Khan, Javed Butler, Laibah Arshad Khan, Markus S. Anker
    2024-12-30
    https://doi.org/10.4081/cardio.2024.58
    3601
    PDF: 658
    HTML: 118
  • Clinical profiles and short-term outcomes of women with peripartum and dilated cardiomyopathies

    Babalawan Muhammad, Naser A. Ishaq, Kamilu M. Karaye
    2024-11-05
    https://doi.org/10.4081/cardio.2024.42
    2299
    PDF: 662
    HTML: 9
  • Frequency of low-density-lipoprotein-cholesterol measurement and risk of major adverse cardiovascular outcomes: a 5-million-person nationwide cohort study

    Denis M. Ngina, Wolfram Doehner, George Ntaios, Yvonne Nartey, Ralph K. Akyea
    2025-09-30
    https://doi.org/10.4081/cardio.2025.85
    566
    PDF: 92
    HTML: 67
  • Importance of patient-reported outcomes in cardiovascular illnesses

    Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan
    2025-06-30
    https://doi.org/10.4081/cardio.2025.69
    2393
    PDF: 558
    HTML: 174
  • Ten-year survival after indirect mitral annuloplasty with the Carillon Mitral Contour System in functional mitral regurgitation. A single-center followup from the REDUCE-FMR trial

    Janusz Lipiecki, Piotr Kalmucki, Larry E. Miller, Nicolas Durel
    2026-06-26
    https://doi.org/10.4081/cardio.2026.106
    11
    PDF: 6
  • Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes

    Asad Gul Rao, Syed Sarmad Javaid, Ahmed Mustafa Rashid, Fawaz Alenezi
    2025-09-15
    https://doi.org/10.4081/cardio.2025.81
    969
    PDF: 600
    HTML: 266
  • Cardiac wasting in patients with advanced cancer: state of the art review

    Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker
    2025-04-16
    https://doi.org/10.4081/cardio.2025.65
    2909
    PDF: 705
    HTML: 71
  • Clinical trial design, endpoints and regulatory considerations in heart failure

    Giuseppe M.C. Rosano
    2024-03-28
    https://doi.org/10.4081/cardio.2024.18
    5954
    PDF: 558
    HTML: 69
  • Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

    Christian Basile, Stefan D. Anker, Gianluigi Savarese
    2025-06-30
    https://doi.org/10.4081/cardio.2025.73
    1022
    PDF: 349
    Supplementary: 196
    Appendix: 148
    HTML: 125
  • Evolving targets for heart failure: the journey so far

    Giuseppe M.C. Rosano, Jerneja Farkas
    2023-11-28
    https://doi.org/10.4081/cardio.2023.6
    2270
    pdf: 439
    HTML: 4
  • Rationale and design for the peripartum cardiomyopathy in Nigeria (PEACE) registry

    Kamilu M. Karaye, Idris Y. Mohammed, Okechukwu S. Ogah, Basil N. Okeahialam
    2023-11-28
    https://doi.org/10.4081/cardio.2023.4
    1179
    pdf: 318
    HTML: 66
  • Is the obesity paradox present in left ventricular assist device recipients? A BMI-based analysis

    Saad Ahmed Waqas, Hibah Siddiqui, Faouzi Kallel, Shahzad Hassan
    2025-09-30
    https://doi.org/10.4081/cardio.2025.84
    375
    PDF: 383
    Supplementary: 182
    HTML: 49
  • Hypertension-related heart failure mortality among older adults in the United States: a nationwide analysis of demographic and regional trends

    Muhammad Muneeb Ur Rehman, Muhammad Sameer Arshad, Muhammad Abdul Tawab, Rahael Javaid, Sunil Modi, Marat Fudim
    2026-03-31
    https://doi.org/10.4081/cardio.2026.97
    1217
    PDF: 309
    SUPPLEMENTARY FILES: 233
    HTML: 134
  • Preliminary study on the immunohistochemical expression of galectin-3 in hypertrophic hearts

    Cecilia Salzillo, Lorenzo Giovannico, Giuseppe Fischetti, Gerardo Cazzato, Mario Magistro, Grazia Nucci, Gabriella Serio, Andrea Marzullo
    2024-06-28
    https://doi.org/10.4081/cardio.2024.37
    1542
    PDF: 408
    HTML: 28
  • Demographic and regional trends of heart failure and cachexia-related mortality among older adults in the United States, from 1999 to 2020

    Ishaque Hameed, Muhammad Nashit, Zahra Quettawala Mufaddal, Syed Sarmad Javaid, Muhammad Hanif
    2025-09-19
    https://doi.org/10.4081/cardio.2025.83
    504
    PDF: 299
    HTML: 73
  • Elevated endostatin is associated with hypertension treatment, elevated high sensitivity C-reactive protein, increased waist-hip ratio, and attenuated kidney function, but not with age, in a middle-aged population

    Anders Larsson, Bertil Wegmann, Toralph Ruge, Joakim Alfredsson, Carl Johan Östgren, Tomas Lindahl
    2025-04-16
    https://doi.org/10.4081/cardio.2025.64
    2860
    PDF: 575
    HTML: 12
  • Epidemiology of peripartum cardiomyopathy in Africa

    Kamilu M. Karaye, Abdulrazaq G. Habib, Karen Sliwa
    2024-06-28
    https://doi.org/10.4081/cardio.2024.31
    2734
    PDF: 583
    HTML: 162
  • Bridging the gap between study outcomes and real-world results. Algorithm-driven management in a rural cardioMEMS population

    Marc Atzenhoefer, Elizabeth Dille, Rebecca Steinke, Nicole Weigert, Keri Sabel, Kirsten Rasmussen
    2025-04-16
    https://doi.org/10.4081/cardio.2025.63
    3745
    PDF: 826
    HTML: 59
  • Impella vs intra-aortic balloon pump in patients with acute myocardial infarction complicated with cardiogenic shock: an updated systematic review and meta-analysis

    Muhammad Ahmed, Serish Bano, Mutahira Asif, F.N.U. Sidra, Meva Ram, Shahida Bibi
    2025-04-16
    https://doi.org/10.4081/cardio.2025.61
    4641
    PDF: 909
    Supplementary: 438
    HTML: 0
  • Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

    Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker
    2024-06-28
    https://doi.org/10.4081/cardio.2024.40
    5809
    PDF: 890
    HTML: 50
  • Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

    Christian Basile, Stefan D. Anker, Gianluigi Savarese
    2025-07-16
    https://doi.org/10.4081/cardio.2025.76
    978
    PDF: 282
    Supplementary: 200
    Appendix: 147
    HTML: 64
  • Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

    Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek
    2024-06-28
    https://doi.org/10.4081/cardio.2024.39
    1835
    PDF: 574
    HTML: 15
  • Early invasive versus conservative strategy in acute coronary syndrome in older adults: systematic review and meta-analysis

    Abu Huraira Bin Gulzar, Mirza Ammar Arshad, Bakhtawara Alam, Syed Sarmad Javaid, Hafsa Azam, Fausto J. Pinto, Evangelos Giannitsis
    2026-06-29
    https://doi.org/10.4081/cardio.2026.107
    0
    PDF: 0
    SUPPLEMENTARY MATERIAL: 0
  • Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

    Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker
    2023-12-27
    https://doi.org/10.4081/cardio.2023.15
    2877
    pdf: 791
    HTML: 51
  • Prevalence of left ventricular dysfunction and relationship with serum selenium in apparently healthy pregnant women: results from the PEACE registry

    Kamilu M. Karaye, Idris Y. Mohammed, Hadiza Sa’idu, Naser A. Ishaq, Suleiman A. Balarabe, Jamilu Tukur, Tewogbade A. Adedeji, Olufemiwa N. Makinde, Rasaaq A. Adebayo
    2024-06-28
    https://doi.org/10.4081/cardio.2024.36
    1723
    PDF: 470
    HTML: 23
  • Carotid artery stenosis related mortality among older adults (>65 years): a retrospective analytical study

    Abu Huraira Bin Gulzar, Ayesha Ahmed Cheema, Hina Nadeem, Syed Sarmad Javaid, Wolfram Doehner, Hafsa Azam
    2026-06-05
    https://doi.org/10.4081/cardio.2026.103
    74
    PDF: 43
    SUPPLEMENTARY FILES: 11
    HTML: 0
  • Intervention options: depression and cardiovascular disease during COVID-19

    Eirini Flouda, Athena Stefanatou, Tinia Apergi
    2023-11-28
    https://doi.org/10.4081/cardio.2023.5
    2007
    pdf: 357
    HTML: 35
  • To clip or not to clip moderate-to-severe functional mitral regurgitation in patients with heart failure?

    Muhammad Shahzeb Khan, Javed Butler, Tim Friede, Piotr Ponikowski, Stefan D. Anker
    2024-11-05
    https://doi.org/10.4081/cardio.2024.44
    3135
    PDF: 864
    HTML: 39
  • Ischemic and bleeding outcomes by diabetes status in patients receiving ticagrelor monotherapy after percutaneous coronary intervention: an updated meta-analysis

    Muhammad Ahmed, Faiqa Iqbal, Muhammad Talha Safdar, Barka Sajid, Muhammad Ahmed Ali Fahim, Salim Surani
    2026-03-31
    https://doi.org/10.4081/cardio.2026.99
    764
    PDF: 278
    SUPPLEMENTARY FILES: 228
    HTML: 92
  • Quality of life in Maltese adults with congenital heart disease: a second look An APPROACH-IS substudy

    Maryanne Caruana, Philip Moons, Adrienne H. Kovacs, Koen Luyckx, Corina Thomet, Werner Budts, Maayke Sluman, Katrine Eriksen, Mikael Dellborg, Malin Berghammer, Bengt Johansson, Alexandra Soufi, Edward Callus, Victor Grech, Silke Apers
    2024-03-28
    https://doi.org/10.4081/cardio.2024.26
    1860
    PDF: 225
    HTML: 9
  • Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

    Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf
    2025-08-20
    https://doi.org/10.4081/cardio.2025.78
    679
    PDF: 478
    Appendix: 256
    HTML: 70
  • iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

    Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano
    2025-09-30
    https://doi.org/10.4081/cardio.2025.86
    3563
    PDF: 3225
    Supplementary: 401
    Appendix: 326
  • How organ care system saved the day during a donation after circulatory death heart transplant: a case of complicated sternal re-entry

    Shiva Seyed Mokhtassi, Nika Majidi, Yousuf Salmasi, Akhil Sonecha, Sanjay Agrawal, Mubassher Husain, Diana Garcia, Jerry Mitchell, Espeed Khoshbin
    2025-04-16
    https://doi.org/10.4081/cardio.2025.60
    3307
    PDF: 633
    HTML: 33
  • Defining iron replete status in patients with heart failure treated with intravenous iron

    Khawaja M. Talha, Javed Butler, Stephan von Haehling, Mitja Lainscak, Piotr Ponikowski, Stefan D. Anker
    2023-12-21
    https://doi.org/10.4081/cardio.2023.17
    3334
    pdf: 469
    HTML: 72
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iCARDIO

May 1 marked the release of the #iCARDIO Guidelines on Heart Failure, now live in Global Cardiology. This global-first effort brings flexible, practical guidance to frontline providers managing #heartfailure in any setting. www.globalcardiology.info/site/article... #GlobalHealth #cardiosky

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— iCardio (@icardio.bsky.social) May 13, 2025 at 8:26

Keywords

Vol. 4 No. 1 (2026)
Draft Document for Public Consultation: iCARDIO Alliance Global Implementation Guidelines on Ischemic Heart Disease Management 2026

Ischemic heart disease (IHD) remains the leading cause of morbidity and mortality worldwide.  Coronary artery disease (CAD) encompasses any pathological process capable of compromising myocardial perfusion and although numerous etiologies exist, including vasculitis, spontaneous coronary artery dissection, and coronary embolism, the majority of CAD is attributable to coronary atherosclerosis, which constitutes the focus of this document. For practical purposes, CAD is considered present when any degree of atherosclerotic involvement...

Writing Task Force | iCARDIO-Alliance
5 February 2026
New papers
Draft Document for Public Consultation: iCARDIO Alliance Global Implementation Guidelines on Obesity Management 2025

Despite the availability of several guidelines, inconsistencies in healthcare access, varying infrastructure, resource constraints and diverse local practices restrict their global applicability. This underscores the need for universal recommendations that address the unique challenges faced by patients and healthcare providers worldwide. Our Global Guidelines emphasize the incorporation of novel therapies, while integrating standard of care with the most up-to-date evidence to enable clinicians to optimize heart failure (HF) management....

Writing Task Force | iCARDIO-Alliance
9 May 2025
Vol. 4 No. 2 (2026)
Carotid artery stenosis related mortality among older adults (>65 years): a retrospective analytical study

Stroke is a leading cause of death, with carotid artery stenosis (CAS) contributing substantially to ischemic events. Although CAS-related strokes remain common in older adults in the United States, mortality patterns and demographic disparities are not well described. We aimed to evaluate nationwide trends and disparities in CAS-related mortality among US adults aged ≥65 years from 1999 to 2020 using the Centers for Disease Control and Prevention’s Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) database. A retrospective...

Abu Huraira Bin Gulzar et al.
5 June 2026
Global Cardiology

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