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• Using multiple primary endpoints in clinical trials with a focus on heart failure

  Stefan D. Anker, Javed Butler, Khawaja M. Talha, Tim Friede

  2024-06-28

  https://doi.org/10.4081/cardio.2024.33

  6638

  PDF: 1027

  HTML: 455

• Clinical trial design, endpoints and regulatory considerations in heart failure

  Giuseppe M.C. Rosano

  2024-03-28

  https://doi.org/10.4081/cardio.2024.18

  6159

  PDF: 696

  HTML: 69

• Effect of metformin and empagliflozin on myocardial function in insulin-resistant patients with heart failure: rationale and design of the METRIS-HF-DZHK18 Trial

  Wolfram Doehner, Tim Friede, Frank Edelmann, Ulf Landmesser, Sebastian Winkler, Burkert Pieske, Fabian Knebel, Sebastian Kelle, Diethelm Tschöpe, Antje Meyer, Nadja Jauert, Marius Placzek, Jeanette Schulz-Menger, Stephan von Haehling, Stefan D. Anker

  2025-12-31

  https://doi.org/10.4081/cardio.2025.89

  576

  PDF: 501

  Appendix: 93

  HTML: 23

• Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

  Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker

  2023-12-27

  https://doi.org/10.4081/cardio.2023.15

  3060

  pdf: 941

  HTML: 78

• Glucagon-like peptide-1 receptor agonists and muscle: interpreting lean mass changes in clinical care

  Muhammad Sameer Arshad, Maaz Ali, Asad Ali Ahmed Cheema, Stefan D. Anker, Andrew J.S. Coats

  2026-03-31

  https://doi.org/10.4081/cardio.2026.101

  1527

  PDF: 763

  HTML: 189

• Cardiac wasting in patients with advanced cancer: state of the art review

  Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker

  2025-04-16

  https://doi.org/10.4081/cardio.2025.65

  3115

  PDF: 868

  HTML: 83

• Ischemic and bleeding outcomes by diabetes status in patients receiving ticagrelor monotherapy after percutaneous coronary intervention: an updated meta-analysis

  Muhammad Ahmed, Faiqa Iqbal, Muhammad Talha Safdar, Barka Sajid, Muhammad Ahmed Ali Fahim, Salim Surani

  2026-03-31

  https://doi.org/10.4081/cardio.2026.99

  894

  PDF: 355

  SUPPLEMENTARY FILES: 271

  HTML: 108

• Metabolic dysfunction-associated steatotic liver disease and cardiovascular disease: a state-of-the-art review

  Aimen Shafiq, Ahmed Mustafa Rashid, Syed Raza Shah, Nicholas W.S. Chew, Wilhelm Haverkamp

  2026-04-10

  https://doi.org/10.4081/cardio.2026.94

  4622

  PDF: 1719

  HTML: 405

• Transcatheter tricuspid valve repair for tricuspid regurgitation: a meta-analysis of MitraClip, TriClip,and PASCAL Systems

  Alina Abbas, Abdul Jabbar, Sajida Moiz Hussain Qamari, Hira Riaz

  2026-07-01

  https://doi.org/10.4081/cardio.2026.104

  965

  PDF: 203

  SUPPLEMENTARY MATERIAL: 139

  HTML: 36

• What is new and what has changed in the 2026 Global Heart Failure Implementation Guidelines and why

  Vijay Chopra, William T. Abraham, Offer Amir, Stefan D. Anker, John J. Atherton, Fernando Bacal, Ralph Stephan von Bardeleben, Dulce Brito, Lucrecia Maria Burgos, Javed Butler, Maria Rosa Costanzo, Albertino Damasceno, Justin A. Ezekowitz, Ishaque Hameed, Sivadasanpillai Harikrishnan, Anuradha Lala, Ileana L. Piña, Clara Saldarriaga, David Sim , John R. Teerlink, Nqoba Tsabedze, Hiroyuki Tsutsui, Jing Yu, Yuhui Zhang, Mohammad Zubaid, Nikhil Balankhe, John G.F. Cleland, Gemma Figtree, Gerasimos Filippatos, Marat Fudim, Habib Gamra, Juan Esteban Gomez-Mesa, Martha Gulati, James L. Januzzi, Marvin A. Konstam, JoAnn Lindenfeld, Robert J. Mentz, Rhonda Monroe, Elijah Ogola, Fausto J. Pinto, Girish C. Rajadhyaksha, Carlos E. Ramos, Giuseppe Rosano, Victor Rossel, Naoki Sato, P. Christian Schulze, Andrew Sindone, Kadhim Sulaiman, Muthiah Vaduganathan, Harriette G.C. Van Spall, Dirk J. van Veldhuisen, Stephan von Haehling, Tzung-Dau Wang, Pepe Zamorano, Michael Böhm, Andrew J.S. Coats, Shelley Zieroth

  2026-08-24

  https://doi.org/10.4081/cardio.2026.118

  801

  PDF: 554

  APPENDIX: 104

  HTML: 28

• To clip or not to clip moderate-to-severe functional mitral regurgitation in patients with heart failure?

  Muhammad Shahzeb Khan, Javed Butler, Tim Friede, Piotr Ponikowski, Stefan D. Anker

  2024-11-05

  https://doi.org/10.4081/cardio.2024.44

  3225

  PDF: 972

  HTML: 52

• Beyond oral and intravenous diuretics: intranasal bumetanide for heart failure decongestion

  Hafsa Azam, Markus S. Anker, Ovidiu Chioncel, Muhammad Shahzeb Khan, Javed Butler

  2026-07-10

  https://doi.org/10.4081/cardio.2026.109

  386

  PDF: 188

  HTML: 16

• Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

  Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker

  2024-06-28

  https://doi.org/10.4081/cardio.2024.40

  6126

  PDF: 1028

  HTML: 77

• Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

  Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf

  2025-08-20

  https://doi.org/10.4081/cardio.2025.78

  878

  PDF: 585

  Appendix: 316

  HTML: 93

• Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-06-30

  https://doi.org/10.4081/cardio.2025.73

  1200

  PDF: 469

  Supplementary: 271

  Appendix: 206

  HTML: 158
• 

  Importance of patient-reported outcomes in cardiovascular illnesses

  Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan

  2025-06-30

  https://doi.org/10.4081/cardio.2025.69

  2552

  PDF: 685

  HTML: 206

• Beyond trial neutrality: treatment discontinuation and the hidden signal in SPIRIT-HF trial

  Viana Copeland, Andrew J.S. Coats

  2026-03-31

  https://doi.org/10.4081/cardio.2026.100

  1556

  PDF: 460

  HTML: 274
• 

  The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

  Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus

  2025-06-30

  https://doi.org/10.4081/cardio.2025.67

  3265

  PDF: 711

  HTML: 165

• Filling the void: digoxin and the first randomized evidence in rheumatic heart disease

  Viana Copeland, Andrew J.S. Coats, Javed Butler, Stefan D. Anker

  2026-07-03

  https://doi.org/10.4081/cardio.2026.108

  555

  PDF: 222

  HTML: 34

• Demographic and regional trends of heart failure and cachexia-related mortality among older adults in the United States, from 1999 to 2020

  Ishaque Hameed, Muhammad Nashit, Zahra Quettawala Mufaddal, Syed Sarmad Javaid, Muhammad Hanif

  2025-09-19

  https://doi.org/10.4081/cardio.2025.83

  717

  PDF: 534

  HTML: 97

• SMART-HF: structured management approach to remote treatment of heart failure. Guiding best practices

  Marc Atzenhoefer, Tamar Atzenhoefer, Hussain Boxwala, Brooke Nelson, Michelle Staudacher, Fahad Iqbal

  2026-09-11

  https://doi.org/10.4081/cardio.2026.116

  110

  PDF: 122

  HTML: 3

• Bridging the gap between study outcomes and real-world results. Algorithm-driven management in a rural cardioMEMS population

  Marc Atzenhoefer, Elizabeth Dille, Rebecca Steinke, Nicole Weigert, Keri Sabel, Kirsten Rasmussen

  2025-04-16

  https://doi.org/10.4081/cardio.2025.63

  4058

  PDF: 966

  HTML: 81

• Early invasive versus conservative strategy in acute coronary syndrome in older adults: systematic review and meta-analysis

  Abu Huraira Bin Gulzar, Mirza Ammar Arshad, Bakhtawara Alam, Syed Sarmad Javaid, Hafsa Azam, Fausto J. Pinto, Evangelos Giannitsis

  2026-06-29

  https://doi.org/10.4081/cardio.2026.107

  474

  PDF: 212

  SUPPLEMENTARY MATERIAL: 139

  HTML: 35

• 2026 iCARDIO Alliance Global Implementation Guidelines on Heart Failure

  Vijay Chopra, William T. Abraham, Offer Amir, Stefan D. Anker, John J. Atherton, Fernando Bacal, Ralph Stephan von Bardeleben , Dulce Brito, Lucrecia Maria Burgos, Javed Butler, Maria Rosa Costanzo, Albertino Damasceno, Justin A. Ezekowitz, Ishaque Hameed, Sivadasanpillai Harikrishnan, Anuradha Lala, Ileana L. Piña, Clara Saldarriaga, David Sim, John R. Teerlink, Nqoba Tsabedze, Hiroyuki Tsutsui, Jing Yu, Yuhui Zhang, Mohammad Zubaid, Nikhil Balankhe, John G.F. Cleland, Gemma Figtree, Gerasimos Filippatos, Marat Fudim, Habib Gamra, Juan Esteban Gomez-Mesa, Martha Gulati, James L. Januzzi, Marvin A. Konstam, JoAnn Lindenfeld, Robert J. Mentz, Rhonda Monroe, Elijah Ogola, Fausto J. Pinto, Girish C. Rajadhyaksha, Carlos E. Ramos, Giuseppe Rosano, Victor Rossel, Naoki Sato, P. Christian Schulze, Andrew Sindone, Kadhim Sulaiman, Muthiah Vaduganathan, Harriette G.C. Van Spall, Dirk J. van Veldhuisen, Stephan von Haehling, Tzung-Dau Wang, Pepe Zamorano, Michael Böhm, Andrew J.S. Coats, Shelley Zieroth

  2026-08-24

  https://doi.org/10.4081/cardio.2026.117

  2643

  PDF: 1472

  APPENDIX: 126

  HTML: 21

• Aldosterone synthase inhibitors in cardio-renal diseases: a state-of-the-art review

  Muhammad Hamza Dawood, Muhammad Shahzeb Khan, Ahmed Mustafa Rashid, Wilhelm Haverkamp

  2025-12-31

  https://doi.org/10.4081/cardio.2025.91

  1118

  PDF: 763

  HTML: 147

• New left ventricular thrombus and embolic events in left ventricular dysfunction postmyocardial infarction

  Ali A. Youssef, Shaima Al-Omani, Mustafa A. Alrefae, Ahmad Suliman, Reem Hassan, Omar Saleh, Zizi S. Khalifa

  2024-11-05

  https://doi.org/10.4081/cardio.2024.43

  2332

  PDF: 871

  HTML: 18

• Familial hypercholesterolemia: state-of-the-art

  Ahmed Kamal Siddiqi, Kumail Mustafa Ali, Rameen Shahid, Shamna Haris, Anandita Kulkarni, Iliyan Mithani, Wilhelm Haverkamp, Muhammad Shahzeb Khan

  2026-06-29

  https://doi.org/10.4081/cardio.2026.102

  2037

  PDF: 1080

  HTML: 92

• Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-07-16

  https://doi.org/10.4081/cardio.2025.76

  1067

  PDF: 422

  Supplementary: 236

  Appendix: 256

  HTML: 76

• Safety of discontinuing oral anticoagulation after atrial fibrillation ablation: an updated systematic review and meta-analysis

  Asad Ali Ahmed Cheema, Ayesha Ahmed Cheema, Azka Shahab, Sara Sohail, Ali Mithani, Muhammad Talha Ayub, Oliviana Geavlete, Markus S. Anker, Wilhelm Haverkamp

  2026-08-21

  https://doi.org/10.4081/cardio.2026.115

  260

  PDF: 123

  SUPPLEMENTARY FILES: 35

  HTML: 14

• The impact of frailty on in-hospital outcomes in patients with HFrEF

  Saad Ahmed Waqas, Taimor Mohammed Khan, Ahmed Kamal Siddiqi, Shahzad Hassan, Stefan D. Anker

  2025-12-17

  https://doi.org/10.4081/cardio.2025.88

  764

  PDF: 350

  Supplementary: 136

  HTML: 34

• Global Cardiology issue highlights

  Andrew J.S. Coats

  2024-06-28

  https://doi.org/10.4081/cardio.2024.41

  3721

  PDF: 533

  HTML: 0

• iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

  Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano

  2025-09-30

  https://doi.org/10.4081/cardio.2025.86

  4778

  PDF: 4221

  Supplementary: 488

  Appendix: 412

• Mineralocorticoid receptor antagonists in heart failure with preserved (and mildly reduced) ejection fraction: a comparative review of spironolactone and finerenone

  Hafsa Azam, Syed Sarmad Javaid, Mahir Karakas

  2026-07-06

  https://doi.org/10.4081/cardio.2026.110

  383

  PDF: 218

  HTML: 31

• Is the obesity paradox present in left ventricular assist device recipients? A BMI-based analysis

  Saad Ahmed Waqas, Hibah Siddiqui, Faouzi Kallel, Shahzad Hassan

  2025-09-30

  https://doi.org/10.4081/cardio.2025.84

  483

  PDF: 508

  Supplementary: 256

  HTML: 67

• The effect of SGLT2 inhibitors on health status in patients with heart failure: a systematic review and meta-analysis

  Muhammad Shariq Usman, Arsalan Hamid, Shurjeel Uddin Qazi, Mikhail N. Kosiborod, Deepak L. Bhatt, Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler

  2024-06-28

  https://doi.org/10.4081/cardio.2024.35

  3879

  PDF: 927

  Conflict of interest: 399

  SUPPLEMENTARY MATERIAL: 356

  HTML: 138