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• iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

  Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano

  2025-09-30

  https://doi.org/10.4081/cardio.2025.86

  4619

  PDF: 4045

  Supplementary: 470

  Appendix: 399

• Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

  Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker

  2024-06-28

  https://doi.org/10.4081/cardio.2024.40

  6081

  PDF: 1000

  HTML: 75

• Ischemic and bleeding outcomes by diabetes status in patients receiving ticagrelor monotherapy after percutaneous coronary intervention: an updated meta-analysis

  Muhammad Ahmed, Faiqa Iqbal, Muhammad Talha Safdar, Barka Sajid, Muhammad Ahmed Ali Fahim, Salim Surani

  2026-03-31

  https://doi.org/10.4081/cardio.2026.99

  867

  PDF: 336

  SUPPLEMENTARY FILES: 262

  HTML: 107

• The effect of SGLT2 inhibitors on health status in patients with heart failure: a systematic review and meta-analysis

  Muhammad Shariq Usman, Arsalan Hamid, Shurjeel Uddin Qazi, Mikhail N. Kosiborod, Deepak L. Bhatt, Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler

  2024-06-28

  https://doi.org/10.4081/cardio.2024.35

  3819

  PDF: 901

  Conflict of interest: 389

  SUPPLEMENTARY MATERIAL: 343

  HTML: 128

• Screening, diagnosis and management of carotid artery stenosis: a state-of-the-art review

  Ahmed Kamal Siddiqi, Safi U. Khan, Iliyan Mithani, Muhammad Shahzeb Khan

  2026-08-21

  https://doi.org/10.4081/cardio.2026.113

  191

  PDF: 162

  HTML: 7

• What is new and what has changed in the 2026 Global Heart Failure Implementation Guidelines and why

  Vijay Chopra, William T. Abraham, Offer Amir, Stefan D. Anker, John J. Atherton, Fernando Bacal, Ralph Stephan von Bardeleben, Dulce Brito, Lucrecia Maria Burgos, Javed Butler, Maria Rosa Costanzo, Albertino Damasceno, Justin A. Ezekowitz, Ishaque Hameed, Sivadasanpillai Harikrishnan, Anuradha Lala, Ileana L. Piña, Clara Saldarriaga, David Sim , John R. Teerlink, Nqoba Tsabedze, Hiroyuki Tsutsui, Jing Yu, Yuhui Zhang, Mohammad Zubaid, Nikhil Balankhe, John G.F. Cleland, Gemma Figtree, Gerasimos Filippatos, Marat Fudim, Habib Gamra, Juan Esteban Gomez-Mesa, Martha Gulati, James L. Januzzi, Marvin A. Konstam, JoAnn Lindenfeld, Robert J. Mentz, Rhonda Monroe, Elijah Ogola, Fausto J. Pinto, Girish C. Rajadhyaksha, Carlos E. Ramos, Giuseppe Rosano, Victor Rossel, Naoki Sato, P. Christian Schulze, Andrew Sindone, Kadhim Sulaiman, Muthiah Vaduganathan, Harriette G.C. Van Spall, Dirk J. van Veldhuisen, Stephan von Haehling, Tzung-Dau Wang, Pepe Zamorano, Michael Böhm, Andrew J.S. Coats, Shelley Zieroth

  2026-08-24

  https://doi.org/10.4081/cardio.2026.118

  598

  PDF: 449

  APPENDIX: 45

  HTML: 7

• Familial hypercholesterolemia: state-of-the-art

  Ahmed Kamal Siddiqi, Kumail Mustafa Ali, Rameen Shahid, Shamna Haris, Anandita Kulkarni, Iliyan Mithani, Wilhelm Haverkamp, Muhammad Shahzeb Khan

  2026-06-29

  https://doi.org/10.4081/cardio.2026.102

  1973

  PDF: 1043

  HTML: 83

• Aldosterone synthase inhibitors in cardio-renal diseases: a state-of-the-art review

  Muhammad Hamza Dawood, Muhammad Shahzeb Khan, Ahmed Mustafa Rashid, Wilhelm Haverkamp

  2025-12-31

  https://doi.org/10.4081/cardio.2025.91

  1079

  PDF: 733

  HTML: 137

• Patent foramen ovale: when does it need closure?

  Aimen Shafiq, Richard A. Krasuski

  2026-03-31

  https://doi.org/10.4081/cardio.2026.98

  1362

  PDF: 407

  HTML: 193

• Early invasive versus conservative strategy in acute coronary syndrome in older adults: systematic review and meta-analysis

  Abu Huraira Bin Gulzar, Mirza Ammar Arshad, Bakhtawara Alam, Syed Sarmad Javaid, Hafsa Azam, Fausto J. Pinto, Evangelos Giannitsis

  2026-06-29

  https://doi.org/10.4081/cardio.2026.107

  441

  PDF: 196

  SUPPLEMENTARY MATERIAL: 121

  HTML: 34

• Safety of discontinuing oral anticoagulation after atrial fibrillation ablation: an updated systematic review and meta-analysis

  Asad Ali Ahmed Cheema, Ayesha Ahmed Cheema, Azka Shahab, Sara Sohail, Ali Mithani, Muhammad Talha Ayub, Oliviana Geavlete, Markus S. Anker, Wilhelm Haverkamp

  2026-08-21

  https://doi.org/10.4081/cardio.2026.115

  195

  PDF: 81

  SUPPLEMENTARY FILES: 15

  HTML: 7

• Using multiple primary endpoints in clinical trials with a focus on heart failure

  Stefan D. Anker, Javed Butler, Khawaja M. Talha, Tim Friede

  2024-06-28

  https://doi.org/10.4081/cardio.2024.33

  6571

  PDF: 1006

  HTML: 440

• Iron supplementation in heart failure and iron deficiency: does it help?

  Laibah Arshad Khan, Syed Sarmad Javaid, Javed Butler

  2025-09-30

  https://doi.org/10.4081/cardio.2025.82

  1120

  PDF: 663

  HTML: 117

• Effect of metformin and empagliflozin on myocardial function in insulin-resistant patients with heart failure: rationale and design of the METRIS-HF-DZHK18 Trial

  Wolfram Doehner, Tim Friede, Frank Edelmann, Ulf Landmesser, Sebastian Winkler, Burkert Pieske, Fabian Knebel, Sebastian Kelle, Diethelm Tschöpe, Antje Meyer, Nadja Jauert, Marius Placzek, Jeanette Schulz-Menger, Stephan von Haehling, Stefan D. Anker

  2025-12-31

  https://doi.org/10.4081/cardio.2025.89

  552

  PDF: 309

  Appendix: 82

  HTML: 20

• Transcatheter tricuspid valve repair for tricuspid regurgitation: a meta-analysis of MitraClip, TriClip,and PASCAL Systems

  Alina Abbas, Abdul Jabbar, Sajida Moiz Hussain Qamari, Hira Riaz

  2026-07-01

  https://doi.org/10.4081/cardio.2026.104

  907

  PDF: 176

  SUPPLEMENTARY MATERIAL: 128

  HTML: 30

• SGLT2 inhibitors and risk reduction for mortality in high-risk patients: a meta-analysis of randomized controlled trials

  Tariq Jamal Siddiqi, Javed Butler, Andrew J.S. Coats, Subodh Verma, Tim Friede, Gerasimos Filippatos, Stefan D. Anker

  2023-11-23

  https://doi.org/10.4081/cardio.2023.2

  1575

  pdf: 426

  Supplementary Material: 103

  HTML: 248

• Aortic valve replacement in asymptomatic severe aortic stenosis. A focused review

  Aimen Shafiq, Rohan Dev Trehan, Mitja Lainscak, Sanjeev Trehan

  2025-12-31

  https://doi.org/10.4081/cardio.2025.93

  586

  PDF: 289

  HTML: 60

• Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

  Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker

  2023-12-27

  https://doi.org/10.4081/cardio.2023.15

  3029

  pdf: 926

  HTML: 72

• 2026 iCARDIO Alliance Global Implementation Guidelines on Heart Failure

  Vijay Chopra, William T. Abraham, Offer Amir, Stefan D. Anker, John J. Atherton, Fernando Bacal, Ralph Stephan von Bardeleben , Dulce Brito, Lucrecia Maria Burgos, Javed Butler, Maria Rosa Costanzo, Albertino Damasceno, Justin A. Ezekowitz, Ishaque Hameed, Sivadasanpillai Harikrishnan, Anuradha Lala, Ileana L. Piña, Clara Saldarriaga, David Sim, John R. Teerlink, Nqoba Tsabedze, Hiroyuki Tsutsui, Jing Yu, Yuhui Zhang, Mohammad Zubaid, Nikhil Balankhe, John G.F. Cleland, Gemma Figtree, Gerasimos Filippatos, Marat Fudim, Habib Gamra, Juan Esteban Gomez-Mesa, Martha Gulati, James L. Januzzi, Marvin A. Konstam, JoAnn Lindenfeld, Robert J. Mentz, Rhonda Monroe, Elijah Ogola, Fausto J. Pinto, Girish C. Rajadhyaksha, Carlos E. Ramos, Giuseppe Rosano, Victor Rossel, Naoki Sato, P. Christian Schulze, Andrew Sindone, Kadhim Sulaiman, Muthiah Vaduganathan, Harriette G.C. Van Spall, Dirk J. van Veldhuisen, Stephan von Haehling, Tzung-Dau Wang, Pepe Zamorano, Michael Böhm, Andrew J.S. Coats, Shelley Zieroth

  2026-08-24

  https://doi.org/10.4081/cardio.2026.117

  2005

  PDF: 1100

  APPENDIX: 68

  HTML: 6

• Evolving targets for heart failure: the journey so far

  Giuseppe M.C. Rosano, Jerneja Farkas

  2023-11-28

  https://doi.org/10.4081/cardio.2023.6

  2489

  pdf: 537

  HTML: 4

• Mineralocorticoid receptor antagonists in heart failure with preserved (and mildly reduced) ejection fraction: a comparative review of spironolactone and finerenone

  Hafsa Azam, Syed Sarmad Javaid, Mahir Karakas

  2026-07-06

  https://doi.org/10.4081/cardio.2026.110

  354

  PDF: 190

  HTML: 27

• Filling the void: digoxin and the first randomized evidence in rheumatic heart disease

  Viana Copeland, Andrew J.S. Coats, Javed Butler, Stefan D. Anker

  2026-07-03

  https://doi.org/10.4081/cardio.2026.108

  529

  PDF: 197

  HTML: 27

• Clinical trial design, endpoints and regulatory considerations in heart failure

  Giuseppe M.C. Rosano

  2024-03-28

  https://doi.org/10.4081/cardio.2024.18

  6110

  PDF: 684

  HTML: 69

• Glucagon-like peptide-1 receptor agonists and muscle: interpreting lean mass changes in clinical care

  Muhammad Sameer Arshad, Maaz Ali, Asad Ali Ahmed Cheema, Stefan D. Anker, Andrew J.S. Coats

  2026-03-31

  https://doi.org/10.4081/cardio.2026.101

  1465

  PDF: 616

  HTML: 176

• Modulation of cardiac metabolism in heart failure

  Giuseppe M.C. Rosano, Andrew J.S. Coats

  2024-11-05

  https://doi.org/10.4081/cardio.2024.30

  2670

  PDF: 1383

  HTML: 109

• Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

  Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf

  2025-08-20

  https://doi.org/10.4081/cardio.2025.78

  836

  PDF: 570

  Appendix: 306

  HTML: 86

• Metabolic dysfunction-associated steatotic liver disease and cardiovascular disease: a state-of-the-art review

  Aimen Shafiq, Ahmed Mustafa Rashid, Syed Raza Shah, Nicholas W.S. Chew, Wilhelm Haverkamp

  2026-04-10

  https://doi.org/10.4081/cardio.2026.94

  4389

  PDF: 1642

  HTML: 364

• iCARDIO Alliance Global Implementation Guidelines on Ischemic Heart Disease 2026

  Fausto J. Pinto, Martha Gulati, Daniel Caldeira, Clara K. Chow, Luis Henrique Wolff Gowdak, Dipti Itchhaporia, Abdulla Shehab, Gurpreet Singh Wander, Beth L. Abramson, Takashi Akasaka, Giuseppe Ambrosio, Alexandra Arias-Mendoza, Otavio Berwanger, Anastase Dzudie, Evangelos Giannitsis, Rania Hammami, Neil Johnson, Vijay Kunadian, Renato D. Lopes, Athanasios Manolis, Girish Mathur, Giuseppe M.C. Rosano, Ana Salvati, Gregg W. Stone, Jean-Claude Tardif, Ping Xie, Jian Zhang, Mohammad Zubaid, William T. Abraham, Wael Abuzeid, Rasha AlBawardy, Thomas Alexander , Stefan D. Anker , John J. Atherton, Andrea Baer, Rakesh Bhadade, William E. Boden, Gabriela Borrayo Sanchez, Javed Butler, Edina Cenko, Edith H. Chavez , Vijay Chopra, Andrew J.S. Coats, Marcelo Di Carli, Jianzeng Dong, Jan Fedacko, Gerasimos Filippatos, Abdoul Kane, Muhammad Shahzeb Khan, Pablos Lamelas, Michael Lee, Haroldo Lopez, Angela H.E.M. Maas, Mpiko Ntsekhe, Pat O’Donnell, Gian Piero Perna, Miguel Quintana, Bagirath Raghuraman, Ruchit Shah, Vladimir Ullauri, Sarah Zaman, Jose Luis Zamorano, Yuhui Zhang, Sheng-hua Zhou, Shelley Zieroth, Rod Zimmermann, Habib Gamra, Maria Ines Sosa Liprandi, Juan-Carlos Kaski

  2026-08-24

  https://doi.org/10.4081/cardio.2026.112

  1346

  PDF: 675

  APPENDIX: 83

  HTML: 9

• Impella vs intra-aortic balloon pump in patients with acute myocardial infarction complicated with cardiogenic shock: an updated systematic review and meta-analysis

  Muhammad Ahmed, Serish Bano, Mutahira Asif, F.N.U. Sidra, Meva Ram, Shahida Bibi

  2025-04-16

  https://doi.org/10.4081/cardio.2025.61

  5325

  PDF: 1113

  Supplementary: 480

  HTML: 0
• 

  Importance of patient-reported outcomes in cardiovascular illnesses

  Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan

  2025-06-30

  https://doi.org/10.4081/cardio.2025.69

  2516

  PDF: 667

  HTML: 204
• 

  The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

  Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus

  2025-06-30

  https://doi.org/10.4081/cardio.2025.67

  3212

  PDF: 689

  HTML: 163

• Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes

  Asad Gul Rao, Syed Sarmad Javaid, Ahmed Mustafa Rashid, Fawaz Alenezi

  2025-09-15

  https://doi.org/10.4081/cardio.2025.81

  1572

  PDF: 772

  HTML: 318

• Intervention options: depression and cardiovascular disease during COVID-19

  Eirini Flouda, Athena Stefanatou, Tinia Apergi

  2023-11-28

  https://doi.org/10.4081/cardio.2023.5

  2116

  pdf: 486

  HTML: 51

• Obesity and left atrial function: state of the art

  Ahmed Mustafa Rashid, Muhammad Shahzeb Khan, Fawaz Alenezi, Stefan D. Anker, Fabian Knebel

  2026-03-31

  https://doi.org/10.4081/cardio.2026.96

  1072

  PDF: 380

  HTML: 156

• Ten-year survival after indirect mitral annuloplasty with the Carillon Mitral Contour System in functional mitral regurgitation. A single-center followup from the REDUCE-FMR trial

  Janusz Lipiecki, Piotr Kalmucki, Larry E. Miller, Nicolas Durel

  2026-06-26

  https://doi.org/10.4081/cardio.2026.106

  489

  PDF: 206

  HTML: 44
• 

  Self-administered intranasal etripamil: a breakthrough in PSVT first-line treatment

  Muddassir Khalid, Aqsa Asif, Sara Rasheed

  2025-07-31

  https://doi.org/10.4081/cardio.2025.79

  1052

  PDF: 465

  HTML: 0

• Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-06-30

  https://doi.org/10.4081/cardio.2025.73

  1172

  PDF: 454

  Supplementary: 259

  Appendix: 198

  HTML: 148

• Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

  Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek

  2024-06-28

  https://doi.org/10.4081/cardio.2024.39

  1994

  PDF: 678

  HTML: 27

• Bridging the gap between study outcomes and real-world results. Algorithm-driven management in a rural cardioMEMS population

  Marc Atzenhoefer, Elizabeth Dille, Rebecca Steinke, Nicole Weigert, Keri Sabel, Kirsten Rasmussen

  2025-04-16

  https://doi.org/10.4081/cardio.2025.63

  4003

  PDF: 946

  HTML: 77

• The scientific targets: the myocardium, the vasculature and the body’s response to heart failure

  Rafael Vidal-Pérez, Ewa A. Jankowska

  2024-03-28

  https://doi.org/10.4081/cardio.2024.19

  3027

  PDF: 460

  HTML: 62

• Safety and efficacy of left atrial appendage closure in cancer versus non-cancer patients: a systematic review and meta-analysis

  Muhammad Ahmed, Fatima Muskan, Mohsin Zaheer, Manesh Kumar, Sawera Gul, Abdul Hadi Ansari, Muhammad Sameer Jamal, Muhammad Sohaib Asghar, M. Chadi Alraies, Shiny Teja Kolli, Praveen Kumar Komminni, Priya Hotwani, Vishal Reddy Bejugam

  2025-06-30

  https://doi.org/10.4081/cardio.2025.72

  1514

  PDF: 467

  Supplementary: 246

  HTML: 169

• The impact of frailty on in-hospital outcomes in patients with HFrEF

  Saad Ahmed Waqas, Taimor Mohammed Khan, Ahmed Kamal Siddiqi, Shahzad Hassan, Stefan D. Anker

  2025-12-17

  https://doi.org/10.4081/cardio.2025.88

  731

  PDF: 329

  Supplementary: 124

  HTML: 31