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Global Cardiology

eISSN 2975-2728

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Editor-in-Chief: Andrew J.S. Coats, Australia

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  • Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

    Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker
    2024-06-28
    https://doi.org/10.4081/cardio.2024.40
    5211
    PDF: 708
    HTML: 16
  • iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

    Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano
    2025-09-30
    https://doi.org/10.4081/cardio.2025.86
    593
    PDF: 1753
    Supplementary: 222
    Appendix: 161
  • Treatment pathways in patients with heart failure with preserved ejection fraction and obesity: perspectives from cardiology specialists and patients

    Javed Butler, Sanjiv J. Shah, Melissa Magwire, Carlos Campos, Muhammad Shariq Usman, Anthony Hoovler, Anup Sabharwal, Barry A. Borlaug
    2024-06-28
    https://doi.org/10.4081/cardio.2024.38
    1833
    PDF: 486
    SUPPLEMENTARY MATERIAL: 291
    GRAPHICAL ABSTRACT: 258
    HTML: 4
  • The Global Implementation Guidelines Initiative: how to optimize cardio-renal-metabolic care worldwide

    Fausto J. Pinto, Stefan D. Anker, William T. Abraham, John J. Atherton, Javed Butler, Vijay Chopra, Andrew J.S. Coats, Yann Colardelle, Maria Rosa Costanzo, Veronica Dean, Gerasimos Filippatos, Martha Gulati, Julio Rosenstock, John Teerlink, Subodh Verma, Jose Luis Zamorano, Yuhui Zhang, Shelley Zieroth
    2025-04-16
    https://doi.org/10.4081/cardio.2025.68
    3236
    PDF: 466
    Appendix: 361
    HTML: 20
  • Acute interventional management of spontaneous coronary artery dissection: case series and literature review

    Enrico Cerrato, Ilaria Meynet, Giorgio Quadri, Federico Giacobbe, Cristina Rolfo, Francesco Tomassini, Fabio Ferrari, Fabio Mariani, Luca Lo Savio, Matteo Bianco, Paola Destefanis, Alessia Luciano, Carol Gravinese, Emanuele Tizzani, Sara Giolitto, Antonella Corleto, Fabrizio D’Ascenzo, Umberto Barbero, Fernando Macaya, Javier Escaned, Roberto Pozzi, Ferdinando Varbella
    2024-03-28
    https://doi.org/10.4081/cardio.2024.22
    3796
    PDF: 158
    HTML: 23
  • Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

    Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf
    2025-08-20
    https://doi.org/10.4081/cardio.2025.78
    234
    PDF: 216
    Appendix: 137
    HTML: 36
  • Lipoprotein(a): what clinicians need to know

    Laibah Arshad Khan, Muhammad Hanif, Ahmed Mustafa Rashid
    2025-09-01
    https://doi.org/10.4081/cardio.2025.80
    151
    PDF: 278
    HTML: 18
  • Global Cardiology issue highlights

    Andrew J.S. Coats
    2024-06-28
    https://doi.org/10.4081/cardio.2024.41
    3435
    PDF: 388
    HTML: 0
  • Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

    Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek
    2024-06-28
    https://doi.org/10.4081/cardio.2024.39
    1431
    PDF: 415
    HTML: 3
  • Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

    Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker
    2023-12-27
    https://doi.org/10.4081/cardio.2023.15
    2416
    pdf: 475
    HTML: 28
  • Welcome to Global Cardiology

    Andrew J.S. Coats
    2023-12-20
    https://doi.org/10.4081/cardio.2023.1
    2292
    pdf: 133
    HTML: 4
  • Applicability of obesity clinical practice guidelines in low- and middle-income countries

    Shelley Zieroth, Fausto Pinto, Stefan D. Anker, William T. Abraham, John J. Atherton, Javed Butler, Vijay Chopra, Andrew J.S. Coats, Martha Gulati, Tammy L. Kindel, José Luis Zamorano, Yuhui Zhang, Linong Ji, Yann Colardelle, Richard B. Weiskopf
    2025-06-30
    https://doi.org/10.4081/cardio.2025.77
    900
    PDF: 473
    Appendix: 131
    HTML: 4
  • Cardiac wasting in patients with advanced cancer: state of the art review

    Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker
    2025-04-16
    https://doi.org/10.4081/cardio.2025.65
    2287
    PDF: 396
    HTML: 17
  • iCARDIO Alliance Global Implementation Guidelines on Heart Failure 2025

    Vijay Chopra, Muhammad Shahzeb Khan, Magdy Abdelhamid, William T. Abraham, Offer Amir, Stefan D. Anker, John J. Atherton, Fernando Bacal, Ralph Stephan von Bardeleben, Dulce Brito, Lucrecia Maria Burgos, Javed Butler, Maria Rosa Costanzo, Albertino Damasceno, Justin A. Ezekowitz, Ishaque Hameed, Sivadasanpillai Harikrishnan, Tiny Jaarsma, Anuradha Lala, Ileana L. Piña, Clara Saldarriaga, David Sim, John R. Teerlink, Nqoba Tsabedze, Hiroyuki Tsutsui, Jing Yu, Yuhui Zhang, Mohammad Zubaid, Nikhil Balankhe, Juan Esteban Gomez-Mesa, James L. Januzzi, Marvin Konstam, Rhonda Monroe, Elijah Ogola, Vinayagam Palaniappan, Mark C. Petrie, Fausto J. Pinto, Girish C. Rajadhyaksha, Amina Rakisheva, Carlos E. Ramos, Victor Rossel, Naoki Sato, P. Christian Schulze, Andrew Sindone, Hadi N. Skouri, Harriette G.C. Van Spall, Aistė Štaraitė, Lynne Warner Stevenson, Kadhim Sulaiman, Tzung-Dau Wang, Michael Böhm, Andrew J.S. Coats, Shelley Zieroth
    2025-06-30
    https://doi.org/10.4081/cardio.2025.70
    9986
    PDF: 6332
    Appendix: 1006
  • Depression, health-related quality of life and life satisfaction in patients with heart failure

    Natasa Sedlar Kobe, Daniel Omersa, Mitja Lainscak, Jerneja Farkas
    2024-11-05
    https://doi.org/10.4081/cardio.2024.47
    2711
    PDF: 635
    HTML: 2
  • Bibliometric analysis of cardiovascular disease research activity in the Arab world

    Hussein H. Khachfe, Marwan M. Refaat
    2024-06-28
    https://doi.org/10.4081/cardio.2024.34
    1858
    PDF: 512
    HTML: 4
  • New left ventricular thrombus and embolic events in left ventricular dysfunction postmyocardial infarction

    Ali A. Youssef, Shaima Al-Omani, Mustafa A. Alrefae, Ahmad Suliman, Reem Hassan, Omar Saleh, Zizi S. Khalifa
    2024-11-05
    https://doi.org/10.4081/cardio.2024.43
    1825
    PDF: 613
    HTML: 2
  • Detection of early heart failure with preserved ejection fraction in metabolic syndrome patients detected as part of a national screening program in middle aged subjects

    Jelena Čelutkienė, Agnė Monika Jakštaitė, Jolita Badarienė, Svetlana Solovjova, Ieva Slivovskaja, Rokas Navickas, Edita Kazėnaitė, Egidija Rinkūnienė, Alma Čypienė, Jonas Misiūra, Ligita Ryliškytė, Aleksandras Laucevičius, Andrew J.S. Coats
    2023-12-29
    https://doi.org/10.4081/cardio.2023.3
    1494
    pdf: 170
    HTML: 4
  • Using multiple primary endpoints in clinical trials with a focus on heart failure

    Stefan D. Anker, Javed Butler, Khawaja M. Talha, Tim Friede
    2024-06-28
    https://doi.org/10.4081/cardio.2024.33
    5384
    PDF: 701
    HTML: 127
  • The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

    Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus
    2025-06-30
    https://doi.org/10.4081/cardio.2025.67
    2013
    PDF: 420
    HTML: 65
  • Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

    Christian Basile, Stefan D. Anker, Gianluigi Savarese
    2025-07-16
    https://doi.org/10.4081/cardio.2025.76
    703
    PDF: 162
    Supplementary: 140
    Appendix: 103
    HTML: 8
  • Demographic and regional trends of heart failure and cachexia-related mortality among older adults in the United States, from 1999 to 2020

    Ishaque Hameed, Muhammad Nashit, Zahra Quettawala Mufaddal, Syed Sarmad Javaid, Muhammad Hanif
    2025-09-19
    https://doi.org/10.4081/cardio.2025.83
    89
    PDF: 114
    HTML: 16
  • Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

    Christian Basile, Stefan D. Anker, Gianluigi Savarese
    2025-06-30
    https://doi.org/10.4081/cardio.2025.73
    699
    PDF: 167
    Supplementary: 133
    Appendix: 105
    HTML: 7
  • Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes

    Asad Gul Rao, Syed Sarmad Javaid, Ahmed Mustafa Rashid, Fawaz Alenezi
    2025-09-15
    https://doi.org/10.4081/cardio.2025.81
    118
    PDF: 161
    HTML: 40
  • The scientific targets: the myocardium, the vasculature and the body’s response to heart failure

    Rafael Vidal-Pérez, Ewa A. Jankowska
    2024-03-28
    https://doi.org/10.4081/cardio.2024.19
    2596
    PDF: 171
    HTML: 19
  • Iron supplementation in heart failure and iron deficiency: does it help?

    Laibah Arshad Khan, Syed Sarmad Javaid, Javed Butler
    2025-09-30
    https://doi.org/10.4081/cardio.2025.82
    81
    PDF: 174
    HTML: 21
  • Defining iron replete status in patients with heart failure treated with intravenous iron

    Khawaja M. Talha, Javed Butler, Stephan von Haehling, Mitja Lainscak, Piotr Ponikowski, Stefan D. Anker
    2023-12-21
    https://doi.org/10.4081/cardio.2023.17
    2859
    pdf: 275
    HTML: 47
  • Quality of life in Maltese adults with congenital heart disease: a second look An APPROACH-IS substudy

    Maryanne Caruana, Philip Moons, Adrienne H. Kovacs, Koen Luyckx, Corina Thomet, Werner Budts, Maayke Sluman, Katrine Eriksen, Mikael Dellborg, Malin Berghammer, Bengt Johansson, Alexandra Soufi, Edward Callus, Victor Grech, Silke Apers
    2024-03-28
    https://doi.org/10.4081/cardio.2024.26
    1589
    PDF: 136
    HTML: 9
  • Epidemiology of peripartum cardiomyopathy in Africa

    Kamilu M. Karaye, Abdulrazaq G. Habib, Karen Sliwa
    2024-06-28
    https://doi.org/10.4081/cardio.2024.31
    2131
    PDF: 470
    HTML: 44
  • Is the obesity paradox present in left ventricular assist device recipients? A BMI-based analysis

    Saad Ahmed Waqas, Hibah Siddiqui, Faouzi Kallel, Shahzad Hassan
    2025-09-30
    https://doi.org/10.4081/cardio.2025.84
    73
    PDF: 124
    Supplementary: 82
    HTML: 11
  • The impact of maternal congenital heart disease on pregnancy outcomes in Malta: a retrospective study

    Maryanne Caruana, Miriam Gatt, Oscar Aquilina, Charles Savona Ventura, Victor Grech, Jane Somerville
    2023-12-29
    https://doi.org/10.4081/cardio.2023.14
    1445
    pdf: 115
    HTML: 2
  • Neck-to-height ratio in Bosnian university students according to the 2017 American College of Cardiology/American Heart Association guidelines on hypertension classification

    Asija Začiragić, Marija Mikić, Amela Dervišević, Orhan Lepara, Nesina Avdagić, Nermina Babić, Almir Fajkić, Amina Valjevac
    2024-03-28
    https://doi.org/10.4081/cardio.2024.27
    1820
    PDF: 186
    HTML: 12
  • Evaluating serum galectin-3 binding protein as a diagnostic and prognostic biomarker in pulmonary arterial hypertension: a comparative study

    Arif Albulushi, Lama S. Alfehaid, Mosaad Alhussein, Amr Youssef
    2024-12-30
    https://doi.org/10.4081/cardio.2024.50
    1673
    PDF: 411
    HTML: 3
  • Adherence to lifestyle therapy in patients with chronic heart failure and comorbidity

    Elena Efremova, Alexander Shutov
    2023-12-20
    https://doi.org/10.4081/cardio.2023.8
    1147
    pdf: 193
    HTML: 12
  • Clinical trial design, endpoints and regulatory considerations in heart failure

    Giuseppe M.C. Rosano
    2024-03-28
    https://doi.org/10.4081/cardio.2024.18
    5571
    PDF: 415
    HTML: 69
  • Mavacamten’s therapeutic impact: cardiac-specific myosin inhibition in obstructive hypertrophic cardiomyopathy

    Ahmad Shabbir, Laiba Yumn, Esha Khan
    2024-11-05
    https://doi.org/10.4081/cardio.2024.48
    2254
    PDF: 566
    HTML: 0
  • Prevalence of left ventricular dysfunction and relationship with serum selenium in apparently healthy pregnant women: results from the PEACE registry

    Kamilu M. Karaye, Idris Y. Mohammed, Hadiza Sa’idu, Naser A. Ishaq, Suleiman A. Balarabe, Jamilu Tukur, Tewogbade A. Adedeji, Olufemiwa N. Makinde, Rasaaq A. Adebayo
    2024-06-28
    https://doi.org/10.4081/cardio.2024.36
    1557
    PDF: 364
    HTML: 1
  • Bridging the gap: integrating stress echocardiography, iFR, CFR, and FFR in the evaluation of coronary artery disease

    Konstantinos Stamos, Theodora Delaporta, Antonios Delaportas
    2025-04-16
    https://doi.org/10.4081/cardio.2025.66
    1225
    PDF: 178
    HTML: 0
  • To clip or not to clip moderate-to-severe functional mitral regurgitation in patients with heart failure?

    Muhammad Shahzeb Khan, Javed Butler, Tim Friede, Piotr Ponikowski, Stefan D. Anker
    2024-11-05
    https://doi.org/10.4081/cardio.2024.44
    2963
    PDF: 745
    HTML: 10
  • Anomalous origin of right coronary artery from the pulmonary artery: an incidental finding on cardiac computed tomography in a patient presenting with dyspnea

    Rachel Anne Xuereb, Sara Xuereb, Kentaro Yamagata, Robert George Xuereb
    2024-03-28
    https://doi.org/10.4081/cardio.2024.24
    1447
    PDF: 137
    HTML: 12
  • Clinical profiles and short-term outcomes of women with peripartum and dilated cardiomyopathies

    Babalawan Muhammad, Naser A. Ishaq, Kamilu M. Karaye
    2024-11-05
    https://doi.org/10.4081/cardio.2024.42
    2035
    PDF: 561
    HTML: 3
  • Advanced cancer as a heart failure like syndrome due to cardiac wasting cardiomyopathy: facts and numbers

    Muhammad Shahzeb Khan, Javed Butler, Laibah Arshad Khan, Markus S. Anker
    2024-12-30
    https://doi.org/10.4081/cardio.2024.58
    2920
    PDF: 482
    HTML: 9
  • Rationale and design for the peripartum cardiomyopathy in Nigeria (PEACE) registry

    Kamilu M. Karaye, Idris Y. Mohammed, Okechukwu S. Ogah, Basil N. Okeahialam
    2023-11-28
    https://doi.org/10.4081/cardio.2023.4
    936
    pdf: 190
    HTML: 40
  • SGLT2 inhibitors and risk reduction for mortality in high-risk patients: a meta-analysis of randomized controlled trials

    Tariq Jamal Siddiqi, Javed Butler, Andrew J.S. Coats, Subodh Verma, Tim Friede, Gerasimos Filippatos, Stefan D. Anker
    2023-11-23
    https://doi.org/10.4081/cardio.2023.2
    1020
    pdf: 210
    Supplementary Material: 35
    HTML: 83
  • Evolving targets for heart failure: the journey so far

    Giuseppe M.C. Rosano, Jerneja Farkas
    2023-11-28
    https://doi.org/10.4081/cardio.2023.6
    1922
    pdf: 275
    HTML: 4
  • Elevated left ventricular end diastolic pressure, chronic pulmonary oedema and valve disease

    Prithwish Banerjee
    2024-04-08
    https://doi.org/10.4081/cardio.2024.23
    1883
    PDF: 136
    HTML: 590
  • Large language models to write scientific manuscripts: to be considered but not trusted

    Christian Basile, Stefan D. Anker, Gianluigi Savarese
    2025-06-30
    https://doi.org/10.4081/cardio.2025.74
    710
    PDF: 170
    HTML: 0
  • Importance of patient-reported outcomes in cardiovascular illnesses

    Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan
    2025-06-30
    https://doi.org/10.4081/cardio.2025.69
    1910
    PDF: 379
    HTML: 79
  • Frequency of low-density-lipoprotein-cholesterol measurement and risk of major adverse cardiovascular outcomes: a 5-million-person nationwide cohort study

    Denis M. Ngina, Wolfram Doehner, George Ntaios, Yvonne Nartey, Ralph K. Akyea
    2025-09-30
    https://doi.org/10.4081/cardio.2025.85
    79
    PDF: 210
    HTML: 13
  • The effect of SGLT2 inhibitors on health status in patients with heart failure: a systematic review and meta-analysis

    Muhammad Shariq Usman, Arsalan Hamid, Shurjeel Uddin Qazi, Mikhail N. Kosiborod, Deepak L. Bhatt, Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler
    2024-06-28
    https://doi.org/10.4081/cardio.2024.35
    2264
    PDF: 622
    Conflict of interest: 310
    SUPPLEMENTARY MATERIAL: 248
    HTML: 28
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iCARDIO

May 1 marked the release of the #iCARDIO Guidelines on Heart Failure, now live in Global Cardiology. This global-first effort brings flexible, practical guidance to frontline providers managing #heartfailure in any setting. www.globalcardiology.info/site/article... #GlobalHealth #cardiosky

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— iCardio (@icardio.bsky.social) May 13, 2025 at 8:26

Keywords

Vol. 3 No. 3 (2025)
iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

There are a number of guidelines on how to manage obesity, but inconsistencies in healthcare access, varying infrastructure, resource constraints and diverse local practices restrict their global applicability. This underscores the need for universal recommendations that address the unique challenges faced by patients and healthcare providers worldwide. Our Global Guidelines emphasize the incorporation of novel therapies, while integrating standards of care with the most up-to-date evidence to enable clinicians to optimize obesity...

Stefan D. Anker et al.
30 September 2025
Vol. 3 No. 2 (2025)
iCARDIO Alliance Global Implementation Guidelines on Heart Failure 2025

Inconsistencies in healthcare access, varying infrastructure, resource constraints and diverse local practices as well as practical and political issues restrict the global applicability of currently available guidelines. There is a need for universal recommendations that address the unique challenges faced by patients and healthcare providers worldwide. Our iCARDIO Alliance Global Implementation Guidelines emphasize the incorporation of novel therapies, while integrating standard of care with the most uptodate evidence to enable...

Vijay Chopra et al.
30 June 2025
Global Cardiology

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