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• Neck-to-height ratio in Bosnian university students according to the 2017 American College of Cardiology/American Heart Association guidelines on hypertension classification

  Asija Začiragić, Marija Mikić, Amela Dervišević, Orhan Lepara, Nesina Avdagić, Nermina Babić, Almir Fajkić, Amina Valjevac

  2024-03-28

  https://doi.org/10.4081/cardio.2024.27

  2232

  PDF: 519

  HTML: 20

• Screening, diagnosis and management of carotid artery stenosis: a state-of-the-art review

  Ahmed Kamal Siddiqi, Safi U. Khan, Iliyan Mithani, Muhammad Shahzeb Khan

  2026-08-21

  https://doi.org/10.4081/cardio.2026.113

  194

  PDF: 162

  HTML: 7

• Bridging the gap between study outcomes and real-world results. Algorithm-driven management in a rural cardioMEMS population

  Marc Atzenhoefer, Elizabeth Dille, Rebecca Steinke, Nicole Weigert, Keri Sabel, Kirsten Rasmussen

  2025-04-16

  https://doi.org/10.4081/cardio.2025.63

  4005

  PDF: 946

  HTML: 77

• The impact of diurnal fasting during Ramadan on patients with established cardiac disease: a systematic review

  Marwan M. Refaat, Nadim El Jamal, Hebah M. El-Rayess, Anthony Gebran, Amar M. Salam

  2024-06-28

  https://doi.org/10.4081/cardio.2024.32

  3540

  PDF: 1399

  HTML: 97

• Detection of early heart failure with preserved ejection fraction in metabolic syndrome patients detected as part of a national screening program in middle aged subjects

  Jelena Čelutkienė, Agnė Monika Jakštaitė, Jolita Badarienė, Svetlana Solovjova, Ieva Slivovskaja, Rokas Navickas, Edita Kazėnaitė, Egidija Rinkūnienė, Alma Čypienė, Jonas Misiūra, Ligita Ryliškytė, Aleksandras Laucevičius, Andrew J.S. Coats

  2023-12-29

  https://doi.org/10.4081/cardio.2023.3

  1879

  pdf: 463

  HTML: 17

• Aldosterone synthase inhibitors in cardio-renal diseases: a state-of-the-art review

  Muhammad Hamza Dawood, Muhammad Shahzeb Khan, Ahmed Mustafa Rashid, Wilhelm Haverkamp

  2025-12-31

  https://doi.org/10.4081/cardio.2025.91

  1079

  PDF: 735

  HTML: 137

• Elevated endostatin is associated with hypertension treatment, elevated high sensitivity C-reactive protein, increased waist-hip ratio, and attenuated kidney function, but not with age, in a middle-aged population

  Anders Larsson, Bertil Wegmann, Toralph Ruge, Joakim Alfredsson, Carl Johan Östgren, Tomas Lindahl

  2025-04-16

  https://doi.org/10.4081/cardio.2025.64

  3003

  PDF: 795

  HTML: 16

• Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

  Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf

  2025-08-20

  https://doi.org/10.4081/cardio.2025.78

  837

  PDF: 571

  Appendix: 308

  HTML: 88

• The association of iron deficiency with right ventricular dysfunction in Africans with heart failure

  Adeseye A. Akintunde, Sope T. Orugun

  2024-12-30

  https://doi.org/10.4081/cardio.2024.53

  2957

  PDF: 497

  Appendix B: 544

  Appendix A: 382

  HTML: 15

• Obesity and left atrial function: state of the art

  Ahmed Mustafa Rashid, Muhammad Shahzeb Khan, Fawaz Alenezi, Stefan D. Anker, Fabian Knebel

  2026-03-31

  https://doi.org/10.4081/cardio.2026.96

  1074

  PDF: 380

  HTML: 156

• 2026 iCARDIO Alliance Global Implementation Guidelines on Heart Failure

  Vijay Chopra, William T. Abraham, Offer Amir, Stefan D. Anker, John J. Atherton, Fernando Bacal, Ralph Stephan von Bardeleben , Dulce Brito, Lucrecia Maria Burgos, Javed Butler, Maria Rosa Costanzo, Albertino Damasceno, Justin A. Ezekowitz, Ishaque Hameed, Sivadasanpillai Harikrishnan, Anuradha Lala, Ileana L. Piña, Clara Saldarriaga, David Sim, John R. Teerlink, Nqoba Tsabedze, Hiroyuki Tsutsui, Jing Yu, Yuhui Zhang, Mohammad Zubaid, Nikhil Balankhe, John G.F. Cleland, Gemma Figtree, Gerasimos Filippatos, Marat Fudim, Habib Gamra, Juan Esteban Gomez-Mesa, Martha Gulati, James L. Januzzi, Marvin A. Konstam, JoAnn Lindenfeld, Robert J. Mentz, Rhonda Monroe, Elijah Ogola, Fausto J. Pinto, Girish C. Rajadhyaksha, Carlos E. Ramos, Giuseppe Rosano, Victor Rossel, Naoki Sato, P. Christian Schulze, Andrew Sindone, Kadhim Sulaiman, Muthiah Vaduganathan, Harriette G.C. Van Spall, Dirk J. van Veldhuisen, Stephan von Haehling, Tzung-Dau Wang, Pepe Zamorano, Michael Böhm, Andrew J.S. Coats, Shelley Zieroth

  2026-08-24

  https://doi.org/10.4081/cardio.2026.117

  2019

  PDF: 1109

  APPENDIX: 83

  HTML: 8

• Prognostic factors and outcome in patients submitted into coronary artery bypass surgery with total arterial myocardial revascularization

  Elias Tassoulas, Dimitrios Tasoulas, Christos Papaconstantinou, Ioannis Chlorogiannis

  2024-12-30

  https://doi.org/10.4081/cardio.2024.46

  3160

  PDF: 621

  HTML: 50

• iCARDIO Alliance Global Implementation Guidelines on Ischemic Heart Disease 2026

  Fausto J. Pinto, Martha Gulati, Daniel Caldeira, Clara K. Chow, Luis Henrique Wolff Gowdak, Dipti Itchhaporia, Abdulla Shehab, Gurpreet Singh Wander, Beth L. Abramson, Takashi Akasaka, Giuseppe Ambrosio, Alexandra Arias-Mendoza, Otavio Berwanger, Anastase Dzudie, Evangelos Giannitsis, Rania Hammami, Neil Johnson, Vijay Kunadian, Renato D. Lopes, Athanasios Manolis, Girish Mathur, Giuseppe M.C. Rosano, Ana Salvati, Gregg W. Stone, Jean-Claude Tardif, Ping Xie, Jian Zhang, Mohammad Zubaid, William T. Abraham, Wael Abuzeid, Rasha AlBawardy, Thomas Alexander , Stefan D. Anker , John J. Atherton, Andrea Baer, Rakesh Bhadade, William E. Boden, Gabriela Borrayo Sanchez, Javed Butler, Edina Cenko, Edith H. Chavez , Vijay Chopra, Andrew J.S. Coats, Marcelo Di Carli, Jianzeng Dong, Jan Fedacko, Gerasimos Filippatos, Abdoul Kane, Muhammad Shahzeb Khan, Pablos Lamelas, Michael Lee, Haroldo Lopez, Angela H.E.M. Maas, Mpiko Ntsekhe, Pat O’Donnell, Gian Piero Perna, Miguel Quintana, Bagirath Raghuraman, Ruchit Shah, Vladimir Ullauri, Sarah Zaman, Jose Luis Zamorano, Yuhui Zhang, Sheng-hua Zhou, Shelley Zieroth, Rod Zimmermann, Habib Gamra, Maria Ines Sosa Liprandi, Juan-Carlos Kaski

  2026-08-24

  https://doi.org/10.4081/cardio.2026.112

  1360

  PDF: 678

  APPENDIX: 90

  HTML: 9

• Clinical profiles and short-term outcomes of women with peripartum and dilated cardiomyopathies

  Babalawan Muhammad, Naser A. Ishaq, Kamilu M. Karaye

  2024-11-05

  https://doi.org/10.4081/cardio.2024.42

  2362

  PDF: 750

  HTML: 22

• Impella vs intra-aortic balloon pump in patients with acute myocardial infarction complicated with cardiogenic shock: an updated systematic review and meta-analysis

  Muhammad Ahmed, Serish Bano, Mutahira Asif, F.N.U. Sidra, Meva Ram, Shahida Bibi

  2025-04-16

  https://doi.org/10.4081/cardio.2025.61

  5328

  PDF: 1117

  Supplementary: 480

  HTML: 0

• Preferential vasodilator effects of levosimendan in resistance pulmonary arteries in a rodent pulmonary embolism model

  Camila Bedo, Juan C. Grignola

  2024-03-28

  https://doi.org/10.4081/cardio.2024.25

  1662

  PDF: 396

  HTML: 22

• Evaluating serum galectin-3 binding protein as a diagnostic and prognostic biomarker in pulmonary arterial hypertension: a comparative study

  Arif Albulushi, Lama S. Alfehaid, Mosaad Alhussein, Amr Youssef

  2024-12-30

  https://doi.org/10.4081/cardio.2024.50

  2117

  PDF: 738

  HTML: 32

• Bridging the gap: integrating stress echocardiography, iFR, CFR, and FFR in the evaluation of coronary artery disease

  Konstantinos Stamos, Theodora Delaporta, Antonios Delaportas

  2025-04-16

  https://doi.org/10.4081/cardio.2025.66

  1693

  PDF: 833

  HTML: 0
• 

  The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

  Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus

  2025-06-30

  https://doi.org/10.4081/cardio.2025.67

  3212

  PDF: 691

  HTML: 163

• Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

  Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker

  2023-12-27

  https://doi.org/10.4081/cardio.2023.15

  3031

  pdf: 927

  HTML: 72

• Elevated left ventricular end diastolic pressure, chronic pulmonary oedema and valve disease

  Prithwish Banerjee

  2024-04-08

  https://doi.org/10.4081/cardio.2024.23

  2616

  PDF: 378

  HTML: 1238

• Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

  Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker

  2024-06-28

  https://doi.org/10.4081/cardio.2024.40

  6082

  PDF: 1000

  HTML: 75

• Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes

  Asad Gul Rao, Syed Sarmad Javaid, Ahmed Mustafa Rashid, Fawaz Alenezi

  2025-09-15

  https://doi.org/10.4081/cardio.2025.81

  1576

  PDF: 772

  HTML: 318

• The scientific targets: the myocardium, the vasculature and the body’s response to heart failure

  Rafael Vidal-Pérez, Ewa A. Jankowska

  2024-03-28

  https://doi.org/10.4081/cardio.2024.19

  3027

  PDF: 460

  HTML: 62

• Frequency of low-density-lipoprotein-cholesterol measurement and risk of major adverse cardiovascular outcomes: a 5-million-person nationwide cohort study

  Denis M. Ngina, Wolfram Doehner, George Ntaios, Yvonne Nartey, Ralph K. Akyea

  2025-09-30

  https://doi.org/10.4081/cardio.2025.85

  815

  PDF: 166

  HTML: 83

• Intervention options: depression and cardiovascular disease during COVID-19

  Eirini Flouda, Athena Stefanatou, Tinia Apergi

  2023-11-28

  https://doi.org/10.4081/cardio.2023.5

  2116

  pdf: 486

  HTML: 51

• Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-06-30

  https://doi.org/10.4081/cardio.2025.73

  1173

  PDF: 454

  Supplementary: 259

  Appendix: 198

  HTML: 150

• Relaxin-2 for heart failure with preserved ejection fraction: a comment on the termination of a phase-II trial investigating the relaxin-2 analogue, LY3540378

  Thomas Bernd Dschietzig, Guy Salama

  2024-12-30

  https://doi.org/10.4081/cardio.2024.56

  5112

  PDF: 1058

  HTML: 138

• Hypertension-related heart failure mortality among older adults in the United States: a nationwide analysis of demographic and regional trends

  Muhammad Muneeb Ur Rehman, Muhammad Sameer Arshad, Muhammad Abdul Tawab, Rahael Javaid, Sunil Modi, Marat Fudim

  2026-03-31

  https://doi.org/10.4081/cardio.2026.97

  1430

  PDF: 399

  SUPPLEMENTARY FILES: 285

  HTML: 166

• The impact of maternal congenital heart disease on pregnancy outcomes in Malta: a retrospective study

  Maryanne Caruana, Miriam Gatt, Oscar Aquilina, Charles Savona Ventura, Victor Grech, Jane Somerville

  2023-12-29

  https://doi.org/10.4081/cardio.2023.14

  1909

  pdf: 298

  HTML: 2

• iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

  Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano

  2025-09-30

  https://doi.org/10.4081/cardio.2025.86

  4621

  PDF: 4046

  Supplementary: 473

  Appendix: 399

• Familial hypercholesterolemia: state-of-the-art

  Ahmed Kamal Siddiqi, Kumail Mustafa Ali, Rameen Shahid, Shamna Haris, Anandita Kulkarni, Iliyan Mithani, Wilhelm Haverkamp, Muhammad Shahzeb Khan

  2026-06-29

  https://doi.org/10.4081/cardio.2026.102

  1975

  PDF: 1046

  HTML: 83

• Modulation of cardiac metabolism in heart failure

  Giuseppe M.C. Rosano, Andrew J.S. Coats

  2024-11-05

  https://doi.org/10.4081/cardio.2024.30

  2670

  PDF: 1383

  HTML: 110

• Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-07-16

  https://doi.org/10.4081/cardio.2025.76

  1046

  PDF: 399

  Supplementary: 227

  Appendix: 245

  HTML: 74

• Treatment pathways in patients with heart failure with preserved ejection fraction and obesity: perspectives from cardiology specialists and patients

  Javed Butler, Sanjiv J. Shah, Melissa Magwire, Carlos Campos, Muhammad Shariq Usman, Anthony Hoovler, Anup Sabharwal, Barry A. Borlaug

  2024-06-28

  https://doi.org/10.4081/cardio.2024.38

  2561

  PDF: 1262

  SUPPLEMENTARY MATERIAL: 397

  GRAPHICAL ABSTRACT: 328

  HTML: 217

• Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

  Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek

  2024-06-28

  https://doi.org/10.4081/cardio.2024.39

  1994

  PDF: 678

  HTML: 27

• Coronary artery calcium scoring. What clinicians need to know

  Syeda Sundus Shah Bokharii, Cristiana Vitale, Eman Khan, Giuseppe M.C. Rosano, Laibah Arshad Khan

  2025-12-11

  https://doi.org/10.4081/cardio.2025.87

  4969

  PDF: 1083

  HTML: 705

• Anomalous origin of right coronary artery from the pulmonary artery: an incidental finding on cardiac computed tomography in a patient presenting with dyspnea

  Rachel Anne Xuereb, Sara Xuereb, Kentaro Yamagata, Robert George Xuereb

  2024-03-28

  https://doi.org/10.4081/cardio.2024.24

  1716

  PDF: 398

  HTML: 25

• Adherence to lifestyle therapy in patients with chronic heart failure and comorbidity

  Elena Efremova, Alexander Shutov

  2023-12-20

  https://doi.org/10.4081/cardio.2023.8

  1533

  pdf: 512

  HTML: 53

• How organ care system saved the day during a donation after circulatory death heart transplant: a case of complicated sternal re-entry

  Shiva Seyed Mokhtassi, Nika Majidi, Yousuf Salmasi, Akhil Sonecha, Sanjay Agrawal, Mubassher Husain, Diana Garcia, Jerry Mitchell, Espeed Khoshbin

  2025-04-16

  https://doi.org/10.4081/cardio.2025.60

  3398

  PDF: 745

  HTML: 40

• Safety and efficacy of left atrial appendage closure in cancer versus non-cancer patients: a systematic review and meta-analysis

  Muhammad Ahmed, Fatima Muskan, Mohsin Zaheer, Manesh Kumar, Sawera Gul, Abdul Hadi Ansari, Muhammad Sameer Jamal, Muhammad Sohaib Asghar, M. Chadi Alraies, Shiny Teja Kolli, Praveen Kumar Komminni, Priya Hotwani, Vishal Reddy Bejugam

  2025-06-30

  https://doi.org/10.4081/cardio.2025.72

  1514

  PDF: 467

  Supplementary: 246

  HTML: 169

• Prevalence of left ventricular dysfunction and relationship with serum selenium in apparently healthy pregnant women: results from the PEACE registry

  Kamilu M. Karaye, Idris Y. Mohammed, Hadiza Sa’idu, Naser A. Ishaq, Suleiman A. Balarabe, Jamilu Tukur, Tewogbade A. Adedeji, Olufemiwa N. Makinde, Rasaaq A. Adebayo

  2024-06-28

  https://doi.org/10.4081/cardio.2024.36

  1785

  PDF: 550

  HTML: 38

• Tricuspid valve fungal endocarditis in a patient with breast cancer and an implantable chemotherapy venous access port

  Petros Fountoulakis, Aikaterini Siama, Aimilianos Kalogeris, Marianthi Iliopoulou, Athanasios Tsoukas, Athanasios Manolis

  2023-12-18

  https://doi.org/10.4081/cardio.2023.7

  944

  pdf: 337

  HTML: 27

• Depression, health-related quality of life and life satisfaction in patients with heart failure

  Natasa Sedlar Kobe, Daniel Omersa, Mitja Lainscak, Jerneja Farkas

  2024-11-05

  https://doi.org/10.4081/cardio.2024.47

  3289

  PDF: 906

  HTML: 21

• Atrial fibrillation during labor unmasking a large left atrial myxoma

  Blanaid Canavan, Rabi Hamadi, Elias Tassoulas

  2026-08-19

  https://doi.org/10.4081/cardio.2026.114

  172

  PDF: 99

  HTML: 0

• Aortic valve replacement in asymptomatic severe aortic stenosis. A focused review

  Aimen Shafiq, Rohan Dev Trehan, Mitja Lainscak, Sanjeev Trehan

  2025-12-31

  https://doi.org/10.4081/cardio.2025.93

  586

  PDF: 289

  HTML: 60

• Epidemiology of peripartum cardiomyopathy in Africa

  Kamilu M. Karaye, Abdulrazaq G. Habib, Karen Sliwa

  2024-06-28

  https://doi.org/10.4081/cardio.2024.31

  2932

  PDF: 648

  HTML: 183

• Metabolic dysfunction-associated steatotic liver disease and cardiovascular disease: a state-of-the-art review

  Aimen Shafiq, Ahmed Mustafa Rashid, Syed Raza Shah, Nicholas W.S. Chew, Wilhelm Haverkamp

  2026-04-10

  https://doi.org/10.4081/cardio.2026.94

  4398

  PDF: 1643

  HTML: 365

• Biological plausibility and implications of obesity associated valvular heart diseases

  Francesco Fioretti, Brian R. Lindman, Javed Butler

  2024-11-05

  https://doi.org/10.4081/cardio.2024.49

  3120

  PDF: 1005

  HTML: 43

• Acute interventional management of spontaneous coronary artery dissection: case series and literature review

  Enrico Cerrato, Ilaria Meynet, Giorgio Quadri, Federico Giacobbe, Cristina Rolfo, Francesco Tomassini, Fabio Ferrari, Fabio Mariani, Luca Lo Savio, Matteo Bianco, Paola Destefanis, Alessia Luciano, Carol Gravinese, Emanuele Tizzani, Sara Giolitto, Antonella Corleto, Fabrizio D’Ascenzo, Umberto Barbero, Fernando Macaya, Javier Escaned, Roberto Pozzi, Ferdinando Varbella

  2024-03-28

  https://doi.org/10.4081/cardio.2024.22

  4169

  PDF: 339

  HTML: 52