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iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano

2025-09-30

https://doi.org/10.4081/cardio.2025.86

828

PDF: 2312

Supplementary: 306

Appendix: 252
SGLT2 inhibitors and risk reduction for mortality in high-risk patients: a meta-analysis of randomized controlled trials

Tariq Jamal Siddiqi, Javed Butler, Andrew J.S. Coats, Subodh Verma, Tim Friede, Gerasimos Filippatos, Stefan D. Anker

2023-11-23

https://doi.org/10.4081/cardio.2023.2

1052

pdf: 234

Supplementary Material: 38

HTML: 104
Frequency of low-density-lipoprotein-cholesterol measurement and risk of major adverse cardiovascular outcomes: a 5-million-person nationwide cohort study

Denis M. Ngina, Wolfram Doehner, George Ntaios, Yvonne Nartey, Ralph K. Akyea

2025-09-30

https://doi.org/10.4081/cardio.2025.85

152

PDF: 400

HTML: 33
Intervention options: depression and cardiovascular disease during COVID-19

Eirini Flouda, Athena Stefanatou, Tinia Apergi

2023-11-28

https://doi.org/10.4081/cardio.2023.5

1750

pdf: 233

HTML: 19
Bibliometric analysis of cardiovascular disease research activity in the Arab world

Hussein H. Khachfe, Marwan M. Refaat

2024-06-28

https://doi.org/10.4081/cardio.2024.34

1906

PDF: 523

HTML: 5
Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

Christian Basile, Stefan D. Anker, Gianluigi Savarese

2025-06-30

https://doi.org/10.4081/cardio.2025.73

730

PDF: 197

Supplementary: 140

Appendix: 110

HTML: 21
Iron supplementation in heart failure and iron deficiency: does it help?

Laibah Arshad Khan, Syed Sarmad Javaid, Javed Butler

2025-09-30

https://doi.org/10.4081/cardio.2025.82

148

PDF: 268

HTML: 32
Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker

2024-06-28

https://doi.org/10.4081/cardio.2024.40

5275

PDF: 721

HTML: 24
Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

Christian Basile, Stefan D. Anker, Gianluigi Savarese

2025-07-16

https://doi.org/10.4081/cardio.2025.76

741

PDF: 182

Supplementary: 145

Appendix: 104

HTML: 28
Cardiac wasting in patients with advanced cancer: state of the art review

Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker

2025-04-16

https://doi.org/10.4081/cardio.2025.65

2348

PDF: 439

HTML: 25
Prognostic factors and outcome in patients submitted into coronary artery bypass surgery with total arterial myocardial revascularization

Elias Tassoulas, Dimitrios Tasoulas, Christos Papaconstantinou, Ioannis Chlorogiannis

2024-12-30

https://doi.org/10.4081/cardio.2024.46

2590

PDF: 437

HTML: 15
The impact of maternal congenital heart disease on pregnancy outcomes in Malta: a retrospective study

Maryanne Caruana, Miriam Gatt, Oscar Aquilina, Charles Savona Ventura, Victor Grech, Jane Somerville

2023-12-29

https://doi.org/10.4081/cardio.2023.14

1483

pdf: 130

HTML: 2
Demographic and regional trends of heart failure and cachexia-related mortality among older adults in the United States, from 1999 to 2020

Ishaque Hameed, Muhammad Nashit, Zahra Quettawala Mufaddal, Syed Sarmad Javaid, Muhammad Hanif

2025-09-19

https://doi.org/10.4081/cardio.2025.83

159

PDF: 187

HTML: 27
Advanced cancer as a heart failure like syndrome due to cardiac wasting cardiomyopathy: facts and numbers

Muhammad Shahzeb Khan, Javed Butler, Laibah Arshad Khan, Markus S. Anker

2024-12-30

https://doi.org/10.4081/cardio.2024.58

3001

PDF: 510

HTML: 42
Defining iron replete status in patients with heart failure treated with intravenous iron

Khawaja M. Talha, Javed Butler, Stephan von Haehling, Mitja Lainscak, Piotr Ponikowski, Stefan D. Anker

2023-12-21

https://doi.org/10.4081/cardio.2023.17

2907

pdf: 296

HTML: 52
Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker

2023-12-27

https://doi.org/10.4081/cardio.2023.15

2489

pdf: 519

HTML: 29
Using multiple primary endpoints in clinical trials with a focus on heart failure

Stefan D. Anker, Javed Butler, Khawaja M. Talha, Tim Friede

2024-06-28

https://doi.org/10.4081/cardio.2024.33

5465

PDF: 709

HTML: 169
COVID-19 myocarditis

Reinaldo B. Bestetti, Rosemary Furlan-Daniel, Luciano P. Pereira

2024-03-28

https://doi.org/10.4081/cardio.2024.21

2654

PDF: 215

HTML: 14
Clinical trial design, endpoints and regulatory considerations in heart failure

Giuseppe M.C. Rosano

2024-03-28

https://doi.org/10.4081/cardio.2024.18

5628

PDF: 444

HTML: 69
Treatment pathways in patients with heart failure with preserved ejection fraction and obesity: perspectives from cardiology specialists and patients

Javed Butler, Sanjiv J. Shah, Melissa Magwire, Carlos Campos, Muhammad Shariq Usman, Anthony Hoovler, Anup Sabharwal, Barry A. Borlaug

2024-06-28

https://doi.org/10.4081/cardio.2024.38

1865

PDF: 503

SUPPLEMENTARY MATERIAL: 295

GRAPHICAL ABSTRACT: 261

HTML: 9
Importance of patient-reported outcomes in cardiovascular illnesses

Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan

2025-06-30

https://doi.org/10.4081/cardio.2025.69

1948

PDF: 407

HTML: 89
Is the obesity paradox present in left ventricular assist device recipients? A BMI-based analysis

Saad Ahmed Waqas, Hibah Siddiqui, Faouzi Kallel, Shahzad Hassan

2025-09-30

https://doi.org/10.4081/cardio.2025.84

127

PDF: 206

Supplementary: 142

HTML: 17
Biological plausibility and implications of obesity associated valvular heart diseases

Francesco Fioretti, Brian R. Lindman, Javed Butler

2024-11-05

https://doi.org/10.4081/cardio.2024.49

2460

PDF: 655

HTML: 1
New left ventricular thrombus and embolic events in left ventricular dysfunction postmyocardial infarction

Ali A. Youssef, Shaima Al-Omani, Mustafa A. Alrefae, Ahmad Suliman, Reem Hassan, Omar Saleh, Zizi S. Khalifa

2024-11-05

https://doi.org/10.4081/cardio.2024.43

1874

PDF: 662

HTML: 3
Evaluating serum galectin-3 binding protein as a diagnostic and prognostic biomarker in pulmonary arterial hypertension: a comparative study

Arif Albulushi, Lama S. Alfehaid, Mosaad Alhussein, Amr Youssef

2024-12-30

https://doi.org/10.4081/cardio.2024.50

1729

PDF: 456

HTML: 3
The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus

2025-06-30

https://doi.org/10.4081/cardio.2025.67

2078

PDF: 440

HTML: 80
How organ care system saved the day during a donation after circulatory death heart transplant: a case of complicated sternal re-entry

Shiva Seyed Mokhtassi, Nika Majidi, Yousuf Salmasi, Akhil Sonecha, Sanjay Agrawal, Mubassher Husain, Diana Garcia, Jerry Mitchell, Espeed Khoshbin

2025-04-16

https://doi.org/10.4081/cardio.2025.60

2786

PDF: 547

HTML: 20
The scientific targets: the myocardium, the vasculature and the body’s response to heart failure

Rafael Vidal-Pérez, Ewa A. Jankowska

2024-03-28

https://doi.org/10.4081/cardio.2024.19

2634

PDF: 191

HTML: 21
To clip or not to clip moderate-to-severe functional mitral regurgitation in patients with heart failure?

Muhammad Shahzeb Khan, Javed Butler, Tim Friede, Piotr Ponikowski, Stefan D. Anker

2024-11-05

https://doi.org/10.4081/cardio.2024.44

2985

PDF: 760

HTML: 14
Adherence to lifestyle therapy in patients with chronic heart failure and comorbidity

Elena Efremova, Alexander Shutov

2023-12-20

https://doi.org/10.4081/cardio.2023.8

1181

pdf: 230

HTML: 14
The muscle hypothesis of shortness of breath in patients with cachexia

Stefan D. Anker, Muhammad Shahzeb Khan, Laibah Arshad Khan, Giuseppe M.C. Rosano, Maurizio Volterrani, Mitja Lainscak, Piotr Ponikowski, Andrew J.S. Coats

2024-12-30

https://doi.org/10.4081/cardio.2024.57

2458

PDF: 636

HTML: 8
Safety and efficacy of left atrial appendage closure in cancer versus non-cancer patients: a systematic review and meta-analysis

Muhammad Ahmed, Fatima Muskan, Mohsin Zaheer, Manesh Kumar, Sawera Gul, Abdul Hadi Ansari, Muhammad Sameer Jamal, Muhammad Sohaib Asghar, M. Chadi Alraies, Shiny Teja Kolli, Praveen Kumar Komminni, Priya Hotwani, Vishal Reddy Bejugam

2025-06-30

https://doi.org/10.4081/cardio.2025.72

1086

PDF: 250

Supplementary: 154

HTML: 81
Clinical profiles and short-term outcomes of women with peripartum and dilated cardiomyopathies

Babalawan Muhammad, Naser A. Ishaq, Kamilu M. Karaye

2024-11-05

https://doi.org/10.4081/cardio.2024.42

2067

PDF: 571

HTML: 3
The effect of SGLT2 inhibitors on health status in patients with heart failure: a systematic review and meta-analysis

Muhammad Shariq Usman, Arsalan Hamid, Shurjeel Uddin Qazi, Mikhail N. Kosiborod, Deepak L. Bhatt, Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler

2024-06-28

https://doi.org/10.4081/cardio.2024.35

2388

PDF: 643

Conflict of interest: 318

SUPPLEMENTARY MATERIAL: 253

HTML: 55
Epidemiology of peripartum cardiomyopathy in Africa

Kamilu M. Karaye, Abdulrazaq G. Habib, Karen Sliwa

2024-06-28

https://doi.org/10.4081/cardio.2024.31

2199

PDF: 490

HTML: 80
Bridging the gap: integrating stress echocardiography, iFR, CFR, and FFR in the evaluation of coronary artery disease

Konstantinos Stamos, Theodora Delaporta, Antonios Delaportas

2025-04-16

https://doi.org/10.4081/cardio.2025.66

1263

PDF: 242

HTML: 0
Evolving targets for heart failure: the journey so far

Giuseppe M.C. Rosano, Jerneja Farkas

2023-11-28

https://doi.org/10.4081/cardio.2023.6

1973

pdf: 312

HTML: 4

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