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• iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

  Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano

  2025-09-30

  https://doi.org/10.4081/cardio.2025.86

  1375

  PDF: 2562

  Supplementary: 321

  Appendix: 268
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  Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

  Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker

  2023-12-27

  https://doi.org/10.4081/cardio.2023.15

  2573

  pdf: 588

  HTML: 31
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  Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

  Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker

  2024-06-28

  https://doi.org/10.4081/cardio.2024.40

  5406

  PDF: 745

  HTML: 30

• Effect of metformin and empagliflozin on myocardial function in insulin-resistant patients with heart failure: rationale and design of the METRIS-HF-DZHK18 Trial

  Wolfram Doehner, Tim Friede, Frank Edelmann, Ulf Landmesser, Sebastian Winkler, Burkert Pieske, Fabian Knebel, Sebastian Kelle, Diethelm Tschöpe, Antje Meyer, Nadja Jauert, Marius Placzek, Jeanette Schulz-Menger, Stephan von Haehling, Stefan D. Anker

  2025-12-31

  https://doi.org/10.4081/cardio.2025.89

  143

  PDF: 46

  Appendix: 18

  HTML: 0

• Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes

  Asad Gul Rao, Syed Sarmad Javaid, Ahmed Mustafa Rashid, Fawaz Alenezi

  2025-09-15

  https://doi.org/10.4081/cardio.2025.81

  403

  PDF: 378

  HTML: 155

• Aldosterone synthase inhibitors in cardio-renal diseases: a state-of-the-art review

  Muhammad Hamza Dawood, Muhammad Shahzeb Khan, Ahmed Mustafa Rashid, Wilhelm Haverkamp

  2025-12-31

  https://doi.org/10.4081/cardio.2025.91

  169

  PDF: 57

  HTML: 2

• Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

  Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf

  2025-08-20

  https://doi.org/10.4081/cardio.2025.78

  406

  PDF: 361

  Appendix: 216

  HTML: 52
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  Using multiple primary endpoints in clinical trials with a focus on heart failure

  Stefan D. Anker, Javed Butler, Khawaja M. Talha, Tim Friede

  2024-06-28

  https://doi.org/10.4081/cardio.2024.33

  5615

  PDF: 747

  HTML: 224

• Cardiac wasting in patients with advanced cancer: state of the art review

  Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker

  2025-04-16

  https://doi.org/10.4081/cardio.2025.65

  2467

  PDF: 511

  HTML: 42
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  Clinical trial design, endpoints and regulatory considerations in heart failure

  Giuseppe M.C. Rosano

  2024-03-28

  https://doi.org/10.4081/cardio.2024.18

  5696

  PDF: 469

  HTML: 69

• Lipoprotein(a): what clinicians need to know

  Laibah Arshad Khan, Muhammad Hanif, Ahmed Mustafa Rashid

  2025-09-01

  https://doi.org/10.4081/cardio.2025.80

  402

  PDF: 750

  HTML: 24

• Aortic valve replacement in asymptomatic severe aortic stenosis. A focused review

  Aimen Shafiq, Rohan Dev Trehan, Mitja Lainscak, Sanjeev Trehan

  2025-12-31

  https://doi.org/10.4081/cardio.2025.93

  129

  PDF: 42

  HTML: 0
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  The effect of SGLT2 inhibitors on health status in patients with heart failure: a systematic review and meta-analysis

  Muhammad Shariq Usman, Arsalan Hamid, Shurjeel Uddin Qazi, Mikhail N. Kosiborod, Deepak L. Bhatt, Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler

  2024-06-28

  https://doi.org/10.4081/cardio.2024.35

  2585

  PDF: 672

  Conflict of interest: 322

  SUPPLEMENTARY MATERIAL: 261

  HTML: 64

• Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-07-16

  https://doi.org/10.4081/cardio.2025.76

  812

  PDF: 199

  Supplementary: 154

  Appendix: 106

  HTML: 39

• Iron supplementation in heart failure and iron deficiency: does it help?

  Laibah Arshad Khan, Syed Sarmad Javaid, Javed Butler

  2025-09-30

  https://doi.org/10.4081/cardio.2025.82

  293

  PDF: 315

  HTML: 55

• Importance of patient-reported outcomes in cardiovascular illnesses

  Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan

  2025-06-30

  https://doi.org/10.4081/cardio.2025.69

  2009

  PDF: 435

  HTML: 110
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  Defining iron replete status in patients with heart failure treated with intravenous iron

  Khawaja M. Talha, Javed Butler, Stephan von Haehling, Mitja Lainscak, Piotr Ponikowski, Stefan D. Anker

  2023-12-21

  https://doi.org/10.4081/cardio.2023.17

  3017

  pdf: 333

  HTML: 56

• Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-06-30

  https://doi.org/10.4081/cardio.2025.73

  808

  PDF: 226

  Supplementary: 146

  Appendix: 112

  HTML: 48
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  The scientific targets: the myocardium, the vasculature and the body’s response to heart failure

  Rafael Vidal-Pérez, Ewa A. Jankowska

  2024-03-28

  https://doi.org/10.4081/cardio.2024.19

  2706

  PDF: 237

  HTML: 21
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  To clip or not to clip moderate-to-severe functional mitral regurgitation in patients with heart failure?

  Muhammad Shahzeb Khan, Javed Butler, Tim Friede, Piotr Ponikowski, Stefan D. Anker

  2024-11-05

  https://doi.org/10.4081/cardio.2024.44

  3021

  PDF: 781

  HTML: 20
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  Rationale and design for the peripartum cardiomyopathy in Nigeria (PEACE) registry

  Kamilu M. Karaye, Idris Y. Mohammed, Okechukwu S. Ogah, Basil N. Okeahialam

  2023-11-28

  https://doi.org/10.4081/cardio.2023.4

  1034

  pdf: 241

  HTML: 51

• Bridging the gap: integrating stress echocardiography, iFR, CFR, and FFR in the evaluation of coronary artery disease

  Konstantinos Stamos, Theodora Delaporta, Antonios Delaportas

  2025-04-16

  https://doi.org/10.4081/cardio.2025.66

  1326

  PDF: 329

  HTML: 0
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  Prognostic factors and outcome in patients submitted into coronary artery bypass surgery with total arterial myocardial revascularization

  Elias Tassoulas, Dimitrios Tasoulas, Christos Papaconstantinou, Ioannis Chlorogiannis

  2024-12-30

  https://doi.org/10.4081/cardio.2024.46

  2671

  PDF: 463

  HTML: 21
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  Modulation of cardiac metabolism in heart failure

  Giuseppe M.C. Rosano, Andrew J.S. Coats

  2024-11-05

  https://doi.org/10.4081/cardio.2024.30

  2372

  PDF: 1162

  HTML: 31
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  The association of iron deficiency with right ventricular dysfunction in Africans with heart failure

  Adeseye A. Akintunde, Sope T. Orugun

  2024-12-30

  https://doi.org/10.4081/cardio.2024.53

  2366

  PDF: 405

  Appendix B: 438

  Appendix A: 323

  HTML: 2

• Impella vs intra-aortic balloon pump in patients with acute myocardial infarction complicated with cardiogenic shock: an updated systematic review and meta-analysis

  Muhammad Ahmed, Serish Bano, Mutahira Asif, F.N.U. Sidra, Meva Ram, Shahida Bibi

  2025-04-16

  https://doi.org/10.4081/cardio.2025.61

  3548

  PDF: 740

  Supplementary: 386

  HTML: 0

• The impact of frailty on in-hospital outcomes in patients with HFrEF

  Saad Ahmed Waqas, Taimor Mohammed Khan, Ahmed Kamal Siddiqi, Shahzad Hassan, Stefan D. Anker

  2025-12-17

  https://doi.org/10.4081/cardio.2025.88

  209

  PDF: 71

  Supplementary: 12

  HTML: 5

• Coronary artery calcium scoring. What clinicians need to know

  Syeda Sundus Shah Bokharii, Cristiana Vitale, Eman Khan, Giuseppe M.C. Rosano, Laibah Arshad Khan

  2025-12-11

  https://doi.org/10.4081/cardio.2025.87

  585

  PDF: 189

  HTML: 46

• Bridging the gap between study outcomes and real-world results. Algorithm-driven management in a rural cardioMEMS population

  Marc Atzenhoefer, Elizabeth Dille, Rebecca Steinke, Nicole Weigert, Keri Sabel, Kirsten Rasmussen

  2025-04-16

  https://doi.org/10.4081/cardio.2025.63

  3192

  PDF: 649

  HTML: 20
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  Acute interventional management of spontaneous coronary artery dissection: case series and literature review

  Enrico Cerrato, Ilaria Meynet, Giorgio Quadri, Federico Giacobbe, Cristina Rolfo, Francesco Tomassini, Fabio Ferrari, Fabio Mariani, Luca Lo Savio, Matteo Bianco, Paola Destefanis, Alessia Luciano, Carol Gravinese, Emanuele Tizzani, Sara Giolitto, Antonella Corleto, Fabrizio D’Ascenzo, Umberto Barbero, Fernando Macaya, Javier Escaned, Roberto Pozzi, Ferdinando Varbella

  2024-03-28

  https://doi.org/10.4081/cardio.2024.22

  3907

  PDF: 190

  HTML: 39
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  Intervention options: depression and cardiovascular disease during COVID-19

  Eirini Flouda, Athena Stefanatou, Tinia Apergi

  2023-11-28

  https://doi.org/10.4081/cardio.2023.5

  1830

  pdf: 260

  HTML: 21

• The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

  Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus

  2025-06-30

  https://doi.org/10.4081/cardio.2025.67

  2214

  PDF: 478

  HTML: 113
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  New left ventricular thrombus and embolic events in left ventricular dysfunction postmyocardial infarction

  Ali A. Youssef, Shaima Al-Omani, Mustafa A. Alrefae, Ahmad Suliman, Reem Hassan, Omar Saleh, Zizi S. Khalifa

  2024-11-05

  https://doi.org/10.4081/cardio.2024.43

  1936

  PDF: 699

  HTML: 3

• Is the obesity paradox present in left ventricular assist device recipients? A BMI-based analysis

  Saad Ahmed Waqas, Hibah Siddiqui, Faouzi Kallel, Shahzad Hassan

  2025-09-30

  https://doi.org/10.4081/cardio.2025.84

  200

  PDF: 244

  Supplementary: 151

  HTML: 23
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  SGLT2 inhibitors and risk reduction for mortality in high-risk patients: a meta-analysis of randomized controlled trials

  Tariq Jamal Siddiqi, Javed Butler, Andrew J.S. Coats, Subodh Verma, Tim Friede, Gerasimos Filippatos, Stefan D. Anker

  2023-11-23

  https://doi.org/10.4081/cardio.2023.2

  1161

  pdf: 260

  Supplementary Material: 41

  HTML: 129
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  Preliminary study on the immunohistochemical expression of galectin-3 in hypertrophic hearts

  Cecilia Salzillo, Lorenzo Giovannico, Giuseppe Fischetti, Gerardo Cazzato, Mario Magistro, Grazia Nucci, Gabriella Serio, Andrea Marzullo

  2024-06-28

  https://doi.org/10.4081/cardio.2024.37

  1355

  PDF: 334

  HTML: 12
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  Relaxin-2 for heart failure with preserved ejection fraction: a comment on the termination of a phase-II trial investigating the relaxin-2 analogue, LY3540378

  Thomas Bernd Dschietzig, Guy Salama

  2024-12-30

  https://doi.org/10.4081/cardio.2024.56

  4056

  PDF: 927

  HTML: 88
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  Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

  Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek

  2024-06-28

  https://doi.org/10.4081/cardio.2024.39

  1562

  PDF: 475

  HTML: 4
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  Global Cardiology issue highlights

  Andrew J.S. Coats

  2024-06-28

  https://doi.org/10.4081/cardio.2024.41

  3488

  PDF: 404

  HTML: 0
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  Evolving targets for heart failure: the journey so far

  Giuseppe M.C. Rosano, Jerneja Farkas

  2023-11-28

  https://doi.org/10.4081/cardio.2023.6

  2073

  pdf: 339

  HTML: 4
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  Treatment pathways in patients with heart failure with preserved ejection fraction and obesity: perspectives from cardiology specialists and patients

  Javed Butler, Sanjiv J. Shah, Melissa Magwire, Carlos Campos, Muhammad Shariq Usman, Anthony Hoovler, Anup Sabharwal, Barry A. Borlaug

  2024-06-28

  https://doi.org/10.4081/cardio.2024.38

  1989

  PDF: 528

  SUPPLEMENTARY MATERIAL: 302

  GRAPHICAL ABSTRACT: 265

  HTML: 31
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  The muscle hypothesis of shortness of breath in patients with cachexia

  Stefan D. Anker, Muhammad Shahzeb Khan, Laibah Arshad Khan, Giuseppe M.C. Rosano, Maurizio Volterrani, Mitja Lainscak, Piotr Ponikowski, Andrew J.S. Coats

  2024-12-30

  https://doi.org/10.4081/cardio.2024.57

  2560

  PDF: 737

  HTML: 13
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  Adherence to lifestyle therapy in patients with chronic heart failure and comorbidity

  Elena Efremova, Alexander Shutov

  2023-12-20

  https://doi.org/10.4081/cardio.2023.8

  1249

  pdf: 278

  HTML: 32

• Demographic and regional trends of heart failure and cachexia-related mortality among older adults in the United States, from 1999 to 2020

  Ishaque Hameed, Muhammad Nashit, Zahra Quettawala Mufaddal, Syed Sarmad Javaid, Muhammad Hanif

  2025-09-19

  https://doi.org/10.4081/cardio.2025.83

  242

  PDF: 208

  HTML: 33

• Safety and efficacy of left atrial appendage closure in cancer versus non-cancer patients: a systematic review and meta-analysis

  Muhammad Ahmed, Fatima Muskan, Mohsin Zaheer, Manesh Kumar, Sawera Gul, Abdul Hadi Ansari, Muhammad Sameer Jamal, Muhammad Sohaib Asghar, M. Chadi Alraies, Shiny Teja Kolli, Praveen Kumar Komminni, Priya Hotwani, Vishal Reddy Bejugam

  2025-06-30

  https://doi.org/10.4081/cardio.2025.72

  1149

  PDF: 271

  Supplementary: 161

  HTML: 93

• Large language models to write scientific manuscripts: to be considered but not trusted

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-06-30

  https://doi.org/10.4081/cardio.2025.74

  788

  PDF: 233

  HTML: 5
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  The impact of diurnal fasting during Ramadan on patients with established cardiac disease: a systematic review

  Marwan M. Refaat, Nadim El Jamal, Hebah M. El-Rayess, Anthony Gebran, Amar M. Salam

  2024-06-28

  https://doi.org/10.4081/cardio.2024.32

  2515

  PDF: 897

  HTML: 16