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• iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

  Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano

  2025-09-30

  https://doi.org/10.4081/cardio.2025.86

  4207

  PDF: 3670

  Supplementary: 436

  Appendix: 386

• Familial hypercholesterolemia: state-of-the-art

  Ahmed Kamal Siddiqi, Kumail Mustafa Ali, Rameen Shahid, Shamna Haris, Anandita Kulkarni, Iliyan Mithani, Wilhelm Haverkamp, Muhammad Shahzeb Khan

  2026-06-29

  https://doi.org/10.4081/cardio.2026.102

  1631

  PDF: 733

  HTML: 48

• Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

  Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker

  2023-12-27

  https://doi.org/10.4081/cardio.2023.15

  2969

  pdf: 881

  HTML: 63

• Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

  Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker

  2024-06-28

  https://doi.org/10.4081/cardio.2024.40

  5998

  PDF: 967

  HTML: 65

• Effect of metformin and empagliflozin on myocardial function in insulin-resistant patients with heart failure: rationale and design of the METRIS-HF-DZHK18 Trial

  Wolfram Doehner, Tim Friede, Frank Edelmann, Ulf Landmesser, Sebastian Winkler, Burkert Pieske, Fabian Knebel, Sebastian Kelle, Diethelm Tschöpe, Antje Meyer, Nadja Jauert, Marius Placzek, Jeanette Schulz-Menger, Stephan von Haehling, Stefan D. Anker

  2025-12-31

  https://doi.org/10.4081/cardio.2025.89

  503

  PDF: 224

  Appendix: 77

  HTML: 18

• Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes

  Asad Gul Rao, Syed Sarmad Javaid, Ahmed Mustafa Rashid, Fawaz Alenezi

  2025-09-15

  https://doi.org/10.4081/cardio.2025.81

  1470

  PDF: 726

  HTML: 298

• Aldosterone synthase inhibitors in cardio-renal diseases: a state-of-the-art review

  Muhammad Hamza Dawood, Muhammad Shahzeb Khan, Ahmed Mustafa Rashid, Wilhelm Haverkamp

  2025-12-31

  https://doi.org/10.4081/cardio.2025.91

  1017

  PDF: 587

  HTML: 92

• Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

  Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf

  2025-08-20

  https://doi.org/10.4081/cardio.2025.78

  776

  PDF: 541

  Appendix: 294

  HTML: 76

• Using multiple primary endpoints in clinical trials with a focus on heart failure

  Stefan D. Anker, Javed Butler, Khawaja M. Talha, Tim Friede

  2024-06-28

  https://doi.org/10.4081/cardio.2024.33

  6469

  PDF: 969

  HTML: 391

• Cardiac wasting in patients with advanced cancer: state of the art review

  Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker

  2025-04-16

  https://doi.org/10.4081/cardio.2025.65

  3011

  PDF: 804

  HTML: 77

• Clinical trial design, endpoints and regulatory considerations in heart failure

  Giuseppe M.C. Rosano

  2024-03-28

  https://doi.org/10.4081/cardio.2024.18

  6043

  PDF: 621

  HTML: 69

• Mineralocorticoid receptor antagonists in heart failure with preserved (and mildly reduced) ejection fraction: a comparative review of spironolactone and finerenone

  Hafsa Azam, Syed Sarmad Javaid, Mahir Karakas

  2026-07-06

  https://doi.org/10.4081/cardio.2026.110

  191

  PDF: 78

  HTML: 6

• Patent foramen ovale: when does it need closure?

  Aimen Shafiq, Richard A. Krasuski

  2026-03-31

  https://doi.org/10.4081/cardio.2026.98

  1254

  PDF: 376

  HTML: 172

• Ischemic and bleeding outcomes by diabetes status in patients receiving ticagrelor monotherapy after percutaneous coronary intervention: an updated meta-analysis

  Muhammad Ahmed, Faiqa Iqbal, Muhammad Talha Safdar, Barka Sajid, Muhammad Ahmed Ali Fahim, Salim Surani

  2026-03-31

  https://doi.org/10.4081/cardio.2026.99

  821

  PDF: 319

  SUPPLEMENTARY FILES: 256

  HTML: 99

• Filling the void: digoxin and the first randomized evidence in rheumatic heart disease

  Viana Copeland, Andrew J.S. Coats, Javed Butler, Stefan D. Anker

  2026-07-03

  https://doi.org/10.4081/cardio.2026.108

  237

  PDF: 75

  HTML: 10

• Lipoprotein(a): what clinicians need to know

  Laibah Arshad Khan, Muhammad Hanif, Ahmed Mustafa Rashid

  2025-09-01

  https://doi.org/10.4081/cardio.2025.80

  1458

  PDF: 1463

  HTML: 39

• Aortic valve replacement in asymptomatic severe aortic stenosis. A focused review

  Aimen Shafiq, Rohan Dev Trehan, Mitja Lainscak, Sanjeev Trehan

  2025-12-31

  https://doi.org/10.4081/cardio.2025.93

  546

  PDF: 261

  HTML: 48

• The effect of SGLT2 inhibitors on health status in patients with heart failure: a systematic review and meta-analysis

  Muhammad Shariq Usman, Arsalan Hamid, Shurjeel Uddin Qazi, Mikhail N. Kosiborod, Deepak L. Bhatt, Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler

  2024-06-28

  https://doi.org/10.4081/cardio.2024.35

  3736

  PDF: 880

  Conflict of interest: 380

  SUPPLEMENTARY MATERIAL: 334

  HTML: 116

• Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-07-16

  https://doi.org/10.4081/cardio.2025.76

  1016

  PDF: 336

  Supplementary: 225

  Appendix: 225

  HTML: 70

• Iron supplementation in heart failure and iron deficiency: does it help?

  Laibah Arshad Khan, Syed Sarmad Javaid, Javed Butler

  2025-09-30

  https://doi.org/10.4081/cardio.2025.82

  1036

  PDF: 600

  HTML: 105
• 

  Importance of patient-reported outcomes in cardiovascular illnesses

  Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan

  2025-06-30

  https://doi.org/10.4081/cardio.2025.69

  2478

  PDF: 629

  HTML: 199

• Obesity and left atrial function: state of the art

  Ahmed Mustafa Rashid, Muhammad Shahzeb Khan, Fawaz Alenezi, Stefan D. Anker, Fabian Knebel

  2026-03-31

  https://doi.org/10.4081/cardio.2026.96

  996

  PDF: 356

  HTML: 130

• Defining iron replete status in patients with heart failure treated with intravenous iron

  Khawaja M. Talha, Javed Butler, Stephan von Haehling, Mitja Lainscak, Piotr Ponikowski, Stefan D. Anker

  2023-12-21

  https://doi.org/10.4081/cardio.2023.17

  3386

  pdf: 571

  HTML: 81

• Ten-year survival after indirect mitral annuloplasty with the Carillon Mitral Contour System in functional mitral regurgitation. A single-center followup from the REDUCE-FMR trial

  Janusz Lipiecki, Piotr Kalmucki, Larry E. Miller, Nicolas Durel

  2026-06-26

  https://doi.org/10.4081/cardio.2026.106

  209

  PDF: 77

  HTML: 17

• Beyond trial neutrality: treatment discontinuation and the hidden signal in SPIRIT-HF trial

  Viana Copeland, Andrew J.S. Coats

  2026-03-31

  https://doi.org/10.4081/cardio.2026.100

  1425

  PDF: 406

  HTML: 214

• Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-06-30

  https://doi.org/10.4081/cardio.2025.73

  1117

  PDF: 413

  Supplementary: 242

  Appendix: 173

  HTML: 141

• The scientific targets: the myocardium, the vasculature and the body’s response to heart failure

  Rafael Vidal-Pérez, Ewa A. Jankowska

  2024-03-28

  https://doi.org/10.4081/cardio.2024.19

  2960

  PDF: 390

  HTML: 29

• Transcatheter tricuspid valve repair for tricuspid regurgitation: a meta-analysis of MitraClip, TriClip,and PASCAL Systems

  Alina Abbas, Abdul Jabbar, Sajida Moiz Hussain Qamari, Hira Riaz

  2026-07-01

  https://doi.org/10.4081/cardio.2026.104

  495

  PDF: 76

  SUPPLEMENTARY MATERIAL: 33

  HTML: 7

• To clip or not to clip moderate-to-severe functional mitral regurgitation in patients with heart failure?

  Muhammad Shahzeb Khan, Javed Butler, Tim Friede, Piotr Ponikowski, Stefan D. Anker

  2024-11-05

  https://doi.org/10.4081/cardio.2024.44

  3166

  PDF: 933

  HTML: 43

• Rationale and design for the peripartum cardiomyopathy in Nigeria (PEACE) registry

  Kamilu M. Karaye, Idris Y. Mohammed, Okechukwu S. Ogah, Basil N. Okeahialam

  2023-11-28

  https://doi.org/10.4081/cardio.2023.4

  1227

  pdf: 396

  HTML: 72

• Bridging the gap: integrating stress echocardiography, iFR, CFR, and FFR in the evaluation of coronary artery disease

  Konstantinos Stamos, Theodora Delaporta, Antonios Delaportas

  2025-04-16

  https://doi.org/10.4081/cardio.2025.66

  1665

  PDF: 789

  HTML: 0

• Prognostic factors and outcome in patients submitted into coronary artery bypass surgery with total arterial myocardial revascularization

  Elias Tassoulas, Dimitrios Tasoulas, Christos Papaconstantinou, Ioannis Chlorogiannis

  2024-12-30

  https://doi.org/10.4081/cardio.2024.46

  3104

  PDF: 589

  HTML: 48

• Glucagon-like peptide-1 receptor agonists and muscle: interpreting lean mass changes in clinical care

  Muhammad Sameer Arshad, Maaz Ali, Asad Ali Ahmed Cheema, Stefan D. Anker, Andrew J.S. Coats

  2026-03-31

  https://doi.org/10.4081/cardio.2026.101

  1393

  PDF: 559

  HTML: 170

• Modulation of cardiac metabolism in heart failure

  Giuseppe M.C. Rosano, Andrew J.S. Coats

  2024-11-05

  https://doi.org/10.4081/cardio.2024.30

  2629

  PDF: 1328

  HTML: 92

• The association of iron deficiency with right ventricular dysfunction in Africans with heart failure

  Adeseye A. Akintunde, Sope T. Orugun

  2024-12-30

  https://doi.org/10.4081/cardio.2024.53

  2813

  PDF: 481

  Appendix B: 526

  Appendix A: 376

  HTML: 13

• Metabolic dysfunction-associated steatotic liver disease and cardiovascular disease: a state-of-the-art review

  Aimen Shafiq, Ahmed Mustafa Rashid, Syed Raza Shah, Nicholas W.S. Chew, Wilhelm Haverkamp

  2026-04-10

  https://doi.org/10.4081/cardio.2026.94

  3991

  PDF: 1533

  HTML: 303

• Early invasive versus conservative strategy in acute coronary syndrome in older adults: systematic review and meta-analysis

  Abu Huraira Bin Gulzar, Mirza Ammar Arshad, Bakhtawara Alam, Syed Sarmad Javaid, Hafsa Azam, Fausto J. Pinto, Evangelos Giannitsis

  2026-06-29

  https://doi.org/10.4081/cardio.2026.107

  207

  PDF: 88

  SUPPLEMENTARY MATERIAL: 37

  HTML: 14

• Impella vs intra-aortic balloon pump in patients with acute myocardial infarction complicated with cardiogenic shock: an updated systematic review and meta-analysis

  Muhammad Ahmed, Serish Bano, Mutahira Asif, F.N.U. Sidra, Meva Ram, Shahida Bibi

  2025-04-16

  https://doi.org/10.4081/cardio.2025.61

  5192

  PDF: 1053

  Supplementary: 472

  HTML: 0

• The impact of frailty on in-hospital outcomes in patients with HFrEF

  Saad Ahmed Waqas, Taimor Mohammed Khan, Ahmed Kamal Siddiqi, Shahzad Hassan, Stefan D. Anker

  2025-12-17

  https://doi.org/10.4081/cardio.2025.88

  675

  PDF: 283

  Supplementary: 116

  HTML: 27

• Coronary artery calcium scoring. What clinicians need to know

  Syeda Sundus Shah Bokharii, Cristiana Vitale, Eman Khan, Giuseppe M.C. Rosano, Laibah Arshad Khan

  2025-12-11

  https://doi.org/10.4081/cardio.2025.87

  4464

  PDF: 890

  HTML: 542

• Bridging the gap between study outcomes and real-world results. Algorithm-driven management in a rural cardioMEMS population

  Marc Atzenhoefer, Elizabeth Dille, Rebecca Steinke, Nicole Weigert, Keri Sabel, Kirsten Rasmussen

  2025-04-16

  https://doi.org/10.4081/cardio.2025.63

  3925

  PDF: 909

  HTML: 71

• Acute interventional management of spontaneous coronary artery dissection: case series and literature review

  Enrico Cerrato, Ilaria Meynet, Giorgio Quadri, Federico Giacobbe, Cristina Rolfo, Francesco Tomassini, Fabio Ferrari, Fabio Mariani, Luca Lo Savio, Matteo Bianco, Paola Destefanis, Alessia Luciano, Carol Gravinese, Emanuele Tizzani, Sara Giolitto, Antonella Corleto, Fabrizio D’Ascenzo, Umberto Barbero, Fernando Macaya, Javier Escaned, Roberto Pozzi, Ferdinando Varbella

  2024-03-28

  https://doi.org/10.4081/cardio.2024.22

  4142

  PDF: 306

  HTML: 50

• Intervention options: depression and cardiovascular disease during COVID-19

  Eirini Flouda, Athena Stefanatou, Tinia Apergi

  2023-11-28

  https://doi.org/10.4081/cardio.2023.5

  2068

  pdf: 444

  HTML: 43
• 

  The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

  Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus

  2025-06-30

  https://doi.org/10.4081/cardio.2025.67

  3147

  PDF: 658

  HTML: 156

• New left ventricular thrombus and embolic events in left ventricular dysfunction postmyocardial infarction

  Ali A. Youssef, Shaima Al-Omani, Mustafa A. Alrefae, Ahmad Suliman, Reem Hassan, Omar Saleh, Zizi S. Khalifa

  2024-11-05

  https://doi.org/10.4081/cardio.2024.43

  2246

  PDF: 829

  HTML: 14

• Is the obesity paradox present in left ventricular assist device recipients? A BMI-based analysis

  Saad Ahmed Waqas, Hibah Siddiqui, Faouzi Kallel, Shahzad Hassan

  2025-09-30

  https://doi.org/10.4081/cardio.2025.84

  422

  PDF: 460

  Supplementary: 220

  HTML: 63

• SGLT2 inhibitors and risk reduction for mortality in high-risk patients: a meta-analysis of randomized controlled trials

  Tariq Jamal Siddiqi, Javed Butler, Andrew J.S. Coats, Subodh Verma, Tim Friede, Gerasimos Filippatos, Stefan D. Anker

  2023-11-23

  https://doi.org/10.4081/cardio.2023.2

  1512

  pdf: 400

  Supplementary Material: 96

  HTML: 219

• Preliminary study on the immunohistochemical expression of galectin-3 in hypertrophic hearts

  Cecilia Salzillo, Lorenzo Giovannico, Giuseppe Fischetti, Gerardo Cazzato, Mario Magistro, Grazia Nucci, Gabriella Serio, Andrea Marzullo

  2024-06-28

  https://doi.org/10.4081/cardio.2024.37

  1593

  PDF: 454

  HTML: 33

• Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

  Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek

  2024-06-28

  https://doi.org/10.4081/cardio.2024.39

  1929

  PDF: 648

  HTML: 23

• Relaxin-2 for heart failure with preserved ejection fraction: a comment on the termination of a phase-II trial investigating the relaxin-2 analogue, LY3540378

  Thomas Bernd Dschietzig, Guy Salama

  2024-12-30

  https://doi.org/10.4081/cardio.2024.56

  4985

  PDF: 1030

  HTML: 132