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• Familial hypercholesterolemia: state-of-the-art

  Ahmed Kamal Siddiqi, Kumail Mustafa Ali, Rameen Shahid, Shamna Haris, Anandita Kulkarni, Iliyan Mithani, Wilhelm Haverkamp, Muhammad Shahzeb Khan

  2026-06-29

  https://doi.org/10.4081/cardio.2026.102

  1151

  PDF: 215

  HTML: 36

• iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

  Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano

  2025-09-30

  https://doi.org/10.4081/cardio.2025.86

  3866

  PDF: 3451

  Supplementary: 405

  Appendix: 348

• The effect of SGLT2 inhibitors on health status in patients with heart failure: a systematic review and meta-analysis

  Muhammad Shariq Usman, Arsalan Hamid, Shurjeel Uddin Qazi, Mikhail N. Kosiborod, Deepak L. Bhatt, Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler

  2024-06-28

  https://doi.org/10.4081/cardio.2024.35

  3622

  PDF: 813

  Conflict of interest: 357

  SUPPLEMENTARY MATERIAL: 308

  HTML: 100

• Aldosterone synthase inhibitors in cardio-renal diseases: a state-of-the-art review

  Muhammad Hamza Dawood, Muhammad Shahzeb Khan, Ahmed Mustafa Rashid, Wilhelm Haverkamp

  2025-12-31

  https://doi.org/10.4081/cardio.2025.91

  936

  PDF: 416

  HTML: 60

• Cardiac wasting in patients with advanced cancer: state of the art review

  Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker

  2025-04-16

  https://doi.org/10.4081/cardio.2025.65

  2943

  PDF: 727

  HTML: 75

• Using multiple primary endpoints in clinical trials with a focus on heart failure

  Stefan D. Anker, Javed Butler, Khawaja M. Talha, Tim Friede

  2024-06-28

  https://doi.org/10.4081/cardio.2024.33

  6221

  PDF: 891

  HTML: 361

• Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

  Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker

  2024-06-28

  https://doi.org/10.4081/cardio.2024.40

  5851

  PDF: 908

  HTML: 51

• Ischemic and bleeding outcomes by diabetes status in patients receiving ticagrelor monotherapy after percutaneous coronary intervention: an updated meta-analysis

  Muhammad Ahmed, Faiqa Iqbal, Muhammad Talha Safdar, Barka Sajid, Muhammad Ahmed Ali Fahim, Salim Surani

  2026-03-31

  https://doi.org/10.4081/cardio.2026.99

  791

  PDF: 290

  SUPPLEMENTARY FILES: 238

  HTML: 94

• Clinical trial design, endpoints and regulatory considerations in heart failure

  Giuseppe M.C. Rosano

  2024-03-28

  https://doi.org/10.4081/cardio.2024.18

  5986

  PDF: 571

  HTML: 69

• Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes

  Asad Gul Rao, Syed Sarmad Javaid, Ahmed Mustafa Rashid, Fawaz Alenezi

  2025-09-15

  https://doi.org/10.4081/cardio.2025.81

  1285

  PDF: 643

  HTML: 278

• Early invasive versus conservative strategy in acute coronary syndrome in older adults: systematic review and meta-analysis

  Abu Huraira Bin Gulzar, Mirza Ammar Arshad, Bakhtawara Alam, Syed Sarmad Javaid, Hafsa Azam, Fausto J. Pinto, Evangelos Giannitsis

  2026-06-29

  https://doi.org/10.4081/cardio.2026.107

  90

  PDF: 34

  SUPPLEMENTARY MATERIAL: 11

  HTML: 3
• 

  Importance of patient-reported outcomes in cardiovascular illnesses

  Wardah Rasool, Ahmed Kamal Siddiqi, Laibah Arshad Khan

  2025-06-30

  https://doi.org/10.4081/cardio.2025.69

  2421

  PDF: 580

  HTML: 178

• Patent foramen ovale: when does it need closure?

  Aimen Shafiq, Richard A. Krasuski

  2026-03-31

  https://doi.org/10.4081/cardio.2026.98

  1095

  PDF: 305

  HTML: 153

• Effect of metformin and empagliflozin on myocardial function in insulin-resistant patients with heart failure: rationale and design of the METRIS-HF-DZHK18 Trial

  Wolfram Doehner, Tim Friede, Frank Edelmann, Ulf Landmesser, Sebastian Winkler, Burkert Pieske, Fabian Knebel, Sebastian Kelle, Diethelm Tschöpe, Antje Meyer, Nadja Jauert, Marius Placzek, Jeanette Schulz-Menger, Stephan von Haehling, Stefan D. Anker

  2025-12-31

  https://doi.org/10.4081/cardio.2025.89

  447

  PDF: 160

  Appendix: 53

  HTML: 14

• Iron supplementation in heart failure and iron deficiency: does it help?

  Laibah Arshad Khan, Syed Sarmad Javaid, Javed Butler

  2025-09-30

  https://doi.org/10.4081/cardio.2025.82

  928

  PDF: 500

  HTML: 85

• Lipoprotein(a): what clinicians need to know

  Laibah Arshad Khan, Muhammad Hanif, Ahmed Mustafa Rashid

  2025-09-01

  https://doi.org/10.4081/cardio.2025.80

  1360

  PDF: 1172

  HTML: 36

• Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-07-16

  https://doi.org/10.4081/cardio.2025.76

  994

  PDF: 293

  Supplementary: 203

  Appendix: 202

  HTML: 65

• Transcatheter tricuspid valve repair for tricuspid regurgitation: a meta-analysis of MitraClip, TriClip,and PASCAL Systems

  Alina Abbas, Abdul Jabbar, Sajida Moiz Hussain Qamari, Hira Riaz

  2026-07-01

  https://doi.org/10.4081/cardio.2026.104

  308

  PDF: 24

  SUPPLEMENTARY MATERIAL: 6

  HTML: 0

• Obesity and left atrial function: state of the art

  Ahmed Mustafa Rashid, Muhammad Shahzeb Khan, Fawaz Alenezi, Stefan D. Anker, Fabian Knebel

  2026-03-31

  https://doi.org/10.4081/cardio.2026.96

  906

  PDF: 318

  HTML: 123

• Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

  Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker

  2023-12-27

  https://doi.org/10.4081/cardio.2023.15

  2923

  pdf: 816

  HTML: 54

• Bridging the gap: integrating stress echocardiography, iFR, CFR, and FFR in the evaluation of coronary artery disease

  Konstantinos Stamos, Theodora Delaporta, Antonios Delaportas

  2025-04-16

  https://doi.org/10.4081/cardio.2025.66

  1635

  PDF: 682

  HTML: 0

• Glucagon-like peptide-1 receptor agonists and muscle: interpreting lean mass changes in clinical care

  Muhammad Sameer Arshad, Maaz Ali, Asad Ali Ahmed Cheema, Stefan D. Anker, Andrew J.S. Coats

  2026-03-31

  https://doi.org/10.4081/cardio.2026.101

  1289

  PDF: 492

  HTML: 148

• Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

  Christian Basile, Stefan D. Anker, Gianluigi Savarese

  2025-06-30

  https://doi.org/10.4081/cardio.2025.73

  1074

  PDF: 369

  Supplementary: 205

  Appendix: 152

  HTML: 135

• Metabolic dysfunction-associated steatotic liver disease and cardiovascular disease: a state-of-the-art review

  Aimen Shafiq, Ahmed Mustafa Rashid, Syed Raza Shah, Nicholas W.S. Chew, Wilhelm Haverkamp

  2026-04-10

  https://doi.org/10.4081/cardio.2026.94

  3209

  PDF: 1382

  HTML: 251

• The scientific targets: the myocardium, the vasculature and the body’s response to heart failure

  Rafael Vidal-Pérez, Ewa A. Jankowska

  2024-03-28

  https://doi.org/10.4081/cardio.2024.19

  2927

  PDF: 319

  HTML: 25

• SGLT2 inhibitors and risk reduction for mortality in high-risk patients: a meta-analysis of randomized controlled trials

  Tariq Jamal Siddiqi, Javed Butler, Andrew J.S. Coats, Subodh Verma, Tim Friede, Gerasimos Filippatos, Stefan D. Anker

  2023-11-23

  https://doi.org/10.4081/cardio.2023.2

  1477

  pdf: 356

  Supplementary Material: 74

  HTML: 210

• Filling the void: digoxin and the first randomized evidence in rheumatic heart disease

  Viana Copeland, Andrew J.S. Coats, Javed Butler, Stefan D. Anker

  2026-07-03

  https://doi.org/10.4081/cardio.2026.108

  92

  PDF: 27

  HTML: 1

• Aortic valve replacement in asymptomatic severe aortic stenosis. A focused review

  Aimen Shafiq, Rohan Dev Trehan, Mitja Lainscak, Sanjeev Trehan

  2025-12-31

  https://doi.org/10.4081/cardio.2025.93

  508

  PDF: 203

  HTML: 28

• Modulation of cardiac metabolism in heart failure

  Giuseppe M.C. Rosano, Andrew J.S. Coats

  2024-11-05

  https://doi.org/10.4081/cardio.2024.30

  2593

  PDF: 1276

  HTML: 82

• Defining iron replete status in patients with heart failure treated with intravenous iron

  Khawaja M. Talha, Javed Butler, Stephan von Haehling, Mitja Lainscak, Piotr Ponikowski, Stefan D. Anker

  2023-12-21

  https://doi.org/10.4081/cardio.2023.17

  3358

  pdf: 494

  HTML: 78

• To clip or not to clip moderate-to-severe functional mitral regurgitation in patients with heart failure?

  Muhammad Shahzeb Khan, Javed Butler, Tim Friede, Piotr Ponikowski, Stefan D. Anker

  2024-11-05

  https://doi.org/10.4081/cardio.2024.44

  3147

  PDF: 890

  HTML: 39

• Frequency of low-density-lipoprotein-cholesterol measurement and risk of major adverse cardiovascular outcomes: a 5-million-person nationwide cohort study

  Denis M. Ngina, Wolfram Doehner, George Ntaios, Yvonne Nartey, Ralph K. Akyea

  2025-09-30

  https://doi.org/10.4081/cardio.2025.85

  611

  PDF: 105

  HTML: 69

• Impella vs intra-aortic balloon pump in patients with acute myocardial infarction complicated with cardiogenic shock: an updated systematic review and meta-analysis

  Muhammad Ahmed, Serish Bano, Mutahira Asif, F.N.U. Sidra, Meva Ram, Shahida Bibi

  2025-04-16

  https://doi.org/10.4081/cardio.2025.61

  5054

  PDF: 982

  Supplementary: 450

  HTML: 0

• Ten-year survival after indirect mitral annuloplasty with the Carillon Mitral Contour System in functional mitral regurgitation. A single-center followup from the REDUCE-FMR trial

  Janusz Lipiecki, Piotr Kalmucki, Larry E. Miller, Nicolas Durel

  2026-06-26

  https://doi.org/10.4081/cardio.2026.106

  84

  PDF: 26

  HTML: 6

• Acute interventional management of spontaneous coronary artery dissection: case series and literature review

  Enrico Cerrato, Ilaria Meynet, Giorgio Quadri, Federico Giacobbe, Cristina Rolfo, Francesco Tomassini, Fabio Ferrari, Fabio Mariani, Luca Lo Savio, Matteo Bianco, Paola Destefanis, Alessia Luciano, Carol Gravinese, Emanuele Tizzani, Sara Giolitto, Antonella Corleto, Fabrizio D’Ascenzo, Umberto Barbero, Fernando Macaya, Javier Escaned, Roberto Pozzi, Ferdinando Varbella

  2024-03-28

  https://doi.org/10.4081/cardio.2024.22

  4102

  PDF: 284

  HTML: 46

• Beyond trial neutrality: treatment discontinuation and the hidden signal in SPIRIT-HF trial

  Viana Copeland, Andrew J.S. Coats

  2026-03-31

  https://doi.org/10.4081/cardio.2026.100

  1364

  PDF: 370

  HTML: 191

• Evolving targets for heart failure: the journey so far

  Giuseppe M.C. Rosano, Jerneja Farkas

  2023-11-28

  https://doi.org/10.4081/cardio.2023.6

  2385

  pdf: 458

  HTML: 4

• Advanced cancer as a heart failure like syndrome due to cardiac wasting cardiomyopathy: facts and numbers

  Muhammad Shahzeb Khan, Javed Butler, Laibah Arshad Khan, Markus S. Anker

  2024-12-30

  https://doi.org/10.4081/cardio.2024.58

  3631

  PDF: 681

  HTML: 122

• Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

  Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf

  2025-08-20

  https://doi.org/10.4081/cardio.2025.78

  709

  PDF: 506

  Appendix: 260

  HTML: 72

• The impact of frailty on in-hospital outcomes in patients with HFrEF

  Saad Ahmed Waqas, Taimor Mohammed Khan, Ahmed Kamal Siddiqi, Shahzad Hassan, Stefan D. Anker

  2025-12-17

  https://doi.org/10.4081/cardio.2025.88

  633

  PDF: 249

  Supplementary: 83

  HTML: 25

• Bridging the gap between study outcomes and real-world results. Algorithm-driven management in a rural cardioMEMS population

  Marc Atzenhoefer, Elizabeth Dille, Rebecca Steinke, Nicole Weigert, Keri Sabel, Kirsten Rasmussen

  2025-04-16

  https://doi.org/10.4081/cardio.2025.63

  3857

  PDF: 846

  HTML: 63

• Global Cardiology issue highlights

  Andrew J.S. Coats

  2024-06-28

  https://doi.org/10.4081/cardio.2024.41

  3636

  PDF: 480

  HTML: 0
• 

  The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

  Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus

  2025-06-30

  https://doi.org/10.4081/cardio.2025.67

  2949

  PDF: 605

  HTML: 151

• Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

  Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek

  2024-06-28

  https://doi.org/10.4081/cardio.2024.39

  1868

  PDF: 604

  HTML: 20

• Relaxin-2 for heart failure with preserved ejection fraction: a comment on the termination of a phase-II trial investigating the relaxin-2 analogue, LY3540378

  Thomas Bernd Dschietzig, Guy Salama

  2024-12-30

  https://doi.org/10.4081/cardio.2024.56

  4855

  PDF: 1002

  HTML: 122

• Carotid artery stenosis related mortality among older adults (>65 years): a retrospective analytical study

  Abu Huraira Bin Gulzar, Ayesha Ahmed Cheema, Hina Nadeem, Syed Sarmad Javaid, Wolfram Doehner, Hafsa Azam

  2026-06-05

  https://doi.org/10.4081/cardio.2026.103

  245

  PDF: 63

  SUPPLEMENTARY MATERIAL: 16

  HTML: 6

• Treatment pathways in patients with heart failure with preserved ejection fraction and obesity: perspectives from cardiology specialists and patients

  Javed Butler, Sanjiv J. Shah, Melissa Magwire, Carlos Campos, Muhammad Shariq Usman, Anthony Hoovler, Anup Sabharwal, Barry A. Borlaug

  2024-06-28

  https://doi.org/10.4081/cardio.2024.38

  2451

  PDF: 933

  SUPPLEMENTARY MATERIAL: 351

  GRAPHICAL ABSTRACT: 301

  HTML: 204

• Intervention options: depression and cardiovascular disease during COVID-19

  Eirini Flouda, Athena Stefanatou, Tinia Apergi

  2023-11-28

  https://doi.org/10.4081/cardio.2023.5

  2027

  pdf: 381

  HTML: 40

• Demographic and regional trends of heart failure and cachexia-related mortality among older adults in the United States, from 1999 to 2020

  Ishaque Hameed, Muhammad Nashit, Zahra Quettawala Mufaddal, Syed Sarmad Javaid, Muhammad Hanif

  2025-09-19

  https://doi.org/10.4081/cardio.2025.83

  552

  PDF: 323

  HTML: 77

• Safety and efficacy of left atrial appendage closure in cancer versus non-cancer patients: a systematic review and meta-analysis

  Muhammad Ahmed, Fatima Muskan, Mohsin Zaheer, Manesh Kumar, Sawera Gul, Abdul Hadi Ansari, Muhammad Sameer Jamal, Muhammad Sohaib Asghar, M. Chadi Alraies, Shiny Teja Kolli, Praveen Kumar Komminni, Priya Hotwani, Vishal Reddy Bejugam

  2025-06-30

  https://doi.org/10.4081/cardio.2025.72

  1443

  PDF: 404

  Supplementary: 206

  HTML: 161