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Global Cardiology

eISSN 2975-2728

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Editor-in-Chief: Andrew J.S. Coats, Australia

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  • Obesity and left atrial function: state of the art

    Ahmed Mustafa Rashid, Muhammad Shahzeb Khan, Fawaz Alenezi, Stefan D. Anker, Fabian Knebel
    2026-03-31
    https://doi.org/10.4081/cardio.2026.96
    886
    PDF: 305
    HTML: 111
  • Safety and efficacy of left atrial appendage closure in cancer versus non-cancer patients: a systematic review and meta-analysis

    Muhammad Ahmed, Fatima Muskan, Mohsin Zaheer, Manesh Kumar, Sawera Gul, Abdul Hadi Ansari, Muhammad Sameer Jamal, Muhammad Sohaib Asghar, M. Chadi Alraies, Shiny Teja Kolli, Praveen Kumar Komminni, Priya Hotwani, Vishal Reddy Bejugam
    2025-06-30
    https://doi.org/10.4081/cardio.2025.72
    1428
    PDF: 392
    Supplementary: 199
    HTML: 160
  • Patent foramen ovale: when does it need closure?

    Aimen Shafiq, Richard A. Krasuski
    2026-03-31
    https://doi.org/10.4081/cardio.2026.98
    1069
    PDF: 290
    HTML: 149
  • Biological plausibility and implications of obesity associated valvular heart diseases

    Francesco Fioretti, Brian R. Lindman, Javed Butler
    2024-11-05
    https://doi.org/10.4081/cardio.2024.49
    2906
    PDF: 869
    HTML: 34
  • Advancements in transcatheter tricuspid valve repair and replacement: a state-of-the-art review with echocardiographic outcomes

    Asad Gul Rao, Syed Sarmad Javaid, Ahmed Mustafa Rashid, Fawaz Alenezi
    2025-09-15
    https://doi.org/10.4081/cardio.2025.81
    1134
    PDF: 605
    HTML: 271
  • The impact of frailty on in-hospital outcomes in patients with HFrEF

    Saad Ahmed Waqas, Taimor Mohammed Khan, Ahmed Kamal Siddiqi, Shahzad Hassan, Stefan D. Anker
    2025-12-17
    https://doi.org/10.4081/cardio.2025.88
    618
    PDF: 239
    Supplementary: 81
    HTML: 24
  • The impact of diurnal fasting during Ramadan on patients with established cardiac disease: a systematic review

    Marwan M. Refaat, Nadim El Jamal, Hebah M. El-Rayess, Anthony Gebran, Amar M. Salam
    2024-06-28
    https://doi.org/10.4081/cardio.2024.32
    3361
    PDF: 1242
    HTML: 29
  • Clinical profiles and short-term outcomes of women with peripartum and dilated cardiomyopathies

    Babalawan Muhammad, Naser A. Ishaq, Kamilu M. Karaye
    2024-11-05
    https://doi.org/10.4081/cardio.2024.42
    2304
    PDF: 663
    HTML: 9
  • Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

    Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker
    2024-06-28
    https://doi.org/10.4081/cardio.2024.40
    5821
    PDF: 896
    HTML: 50
  • New left ventricular thrombus and embolic events in left ventricular dysfunction postmyocardial infarction

    Ali A. Youssef, Shaima Al-Omani, Mustafa A. Alrefae, Ahmad Suliman, Reem Hassan, Omar Saleh, Zizi S. Khalifa
    2024-11-05
    https://doi.org/10.4081/cardio.2024.43
    2193
    PDF: 762
    HTML: 11
  • Is the obesity paradox present in left ventricular assist device recipients? A BMI-based analysis

    Saad Ahmed Waqas, Hibah Siddiqui, Faouzi Kallel, Shahzad Hassan
    2025-09-30
    https://doi.org/10.4081/cardio.2025.84
    382
    PDF: 389
    Supplementary: 184
    HTML: 49
  • Carvedilol versus metoprolol in preventing post-operative atrial fibrillation: a systematic review and meta-analysis

    Amir Askarinejad, Erfan Kohansal, Soudabeh Shafiee Ardestani, Mohammadhossein Mozafarybazargany, Hamed Hesami, Amirreza Sabahizadeh, Seyed Abbas Pakmehr, Majid Haghjoo
    2024-12-30
    https://doi.org/10.4081/cardio.2024.51
    4920
    PDF: 485
    Appendix A: 362
    Appendix B: 495
    HTML: 0
  • Pulmonary artery pressure sensor device performance in patients with atrial fibrillation/flutter

    Muhammad Usman Almani, Jafar Alzubi, Muhammad Yousuf, Razan Alrawashdeh, Noor Fatima, Mohammad Al Madani, Raphael Bonita
    2024-12-30
    https://doi.org/10.4081/cardio.2024.55
    2874
    PDF: 485
    APPENDIX: 401
    HTML: 0
  • The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

    Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus
    2025-06-30
    https://doi.org/10.4081/cardio.2025.67
    2817
    PDF: 589
    HTML: 146
  • Sex-based differences in characteristics, management, and outcomes in heart failure with reduced ejection fraction

    Christian Basile, Stefan D. Anker, Gianluigi Savarese
    2025-06-30
    https://doi.org/10.4081/cardio.2025.73
    1040
    PDF: 353
    Supplementary: 196
    Appendix: 148
    HTML: 128
  • Evaluating serum galectin-3 binding protein as a diagnostic and prognostic biomarker in pulmonary arterial hypertension: a comparative study

    Arif Albulushi, Lama S. Alfehaid, Mosaad Alhussein, Amr Youssef
    2024-12-30
    https://doi.org/10.4081/cardio.2024.50
    2010
    PDF: 636
    HTML: 23
  • Iron deficiency in heart failure with preserved ejection fraction: rationale and design of the FAIR-HFpEF trial

    Stephan von Haehling, Wolfram Doehner, Ruben Evertz, Tania Garfias-Veitl, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D. Anker
    2023-12-27
    https://doi.org/10.4081/cardio.2023.15
    2888
    pdf: 795
    HTML: 51
  • Bridging the gap between study outcomes and real-world results. Algorithm-driven management in a rural cardioMEMS population

    Marc Atzenhoefer, Elizabeth Dille, Rebecca Steinke, Nicole Weigert, Keri Sabel, Kirsten Rasmussen
    2025-04-16
    https://doi.org/10.4081/cardio.2025.63
    3826
    PDF: 827
    HTML: 61
  • Beyond trial neutrality: treatment discontinuation and the hidden signal in SPIRIT-HF trial

    Viana Copeland, Andrew J.S. Coats
    2026-03-31
    https://doi.org/10.4081/cardio.2026.100
    1331
    PDF: 364
    HTML: 178
  • Dyslipidemia and stroke-related mortality in the United States: a nationwide analysis for 2010-2020

    Muhammad Muneeb Ur Rehman, Iliyan Mithani, Muhammad Sameer Arshad, Syed Raza Shah, Wolfram Doehner, Anandita Kulkarni
    2025-12-31
    https://doi.org/10.4081/cardio.2025.90
    464
    PDF: 160
    Supplementary: 45
    HTML: 56
  • Depression, health-related quality of life and life satisfaction in patients with heart failure

    Natasa Sedlar Kobe, Daniel Omersa, Mitja Lainscak, Jerneja Farkas
    2024-11-05
    https://doi.org/10.4081/cardio.2024.47
    3215
    PDF: 814
    HTML: 11
  • Intervention options: depression and cardiovascular disease during COVID-19

    Eirini Flouda, Athena Stefanatou, Tinia Apergi
    2023-11-28
    https://doi.org/10.4081/cardio.2023.5
    2016
    pdf: 365
    HTML: 35
  • Anomalous origin of right coronary artery from the pulmonary artery: an incidental finding on cardiac computed tomography in a patient presenting with dyspnea

    Rachel Anne Xuereb, Sara Xuereb, Kentaro Yamagata, Robert George Xuereb
    2024-03-28
    https://doi.org/10.4081/cardio.2024.24
    1636
    PDF: 286
    HTML: 21
  • Global Cardiology issue highlights

    Andrew J.S. Coats
    2024-06-28
    https://doi.org/10.4081/cardio.2024.41
    3629
    PDF: 472
    HTML: 0
  • Elevated left ventricular end diastolic pressure, chronic pulmonary oedema and valve disease

    Prithwish Banerjee
    2024-04-08
    https://doi.org/10.4081/cardio.2024.23
    2335
    PDF: 302
    HTML: 1041
  • Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

    Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek
    2024-06-28
    https://doi.org/10.4081/cardio.2024.39
    1844
    PDF: 589
    HTML: 19
  • Sex differences in clinical characteristics and outcomes in heart failure with mildly reduced and preserved ejection fraction

    Christian Basile, Stefan D. Anker, Gianluigi Savarese
    2025-07-16
    https://doi.org/10.4081/cardio.2025.76
    982
    PDF: 283
    Supplementary: 202
    Appendix: 149
    HTML: 65
  • SGLT2 inhibitors and risk reduction for mortality in high-risk patients: a meta-analysis of randomized controlled trials

    Tariq Jamal Siddiqi, Javed Butler, Andrew J.S. Coats, Subodh Verma, Tim Friede, Gerasimos Filippatos, Stefan D. Anker
    2023-11-23
    https://doi.org/10.4081/cardio.2023.2
    1467
    pdf: 343
    Supplementary Material: 67
    HTML: 203
  • Frequency of low-density-lipoprotein-cholesterol measurement and risk of major adverse cardiovascular outcomes: a 5-million-person nationwide cohort study

    Denis M. Ngina, Wolfram Doehner, George Ntaios, Yvonne Nartey, Ralph K. Akyea
    2025-09-30
    https://doi.org/10.4081/cardio.2025.85
    580
    PDF: 94
    HTML: 67
  • Hypertension-related heart failure mortality among older adults in the United States: a nationwide analysis of demographic and regional trends

    Muhammad Muneeb Ur Rehman, Muhammad Sameer Arshad, Muhammad Abdul Tawab, Rahael Javaid, Sunil Modi, Marat Fudim
    2026-03-31
    https://doi.org/10.4081/cardio.2026.97
    1331
    PDF: 316
    SUPPLEMENTARY FILES: 236
    HTML: 134
  • The Global Implementation Guidelines Initiative: how to optimize cardio-renal-metabolic care worldwide

    Fausto J. Pinto, Stefan D. Anker, William T. Abraham, John J. Atherton, Javed Butler, Vijay Chopra, Andrew J.S. Coats, Yann Colardelle, Maria Rosa Costanzo, Veronica Dean, Gerasimos Filippatos, Martha Gulati, Julio Rosenstock, John Teerlink, Subodh Verma, Jose Luis Zamorano, Yuhui Zhang, Shelley Zieroth
    2025-04-16
    https://doi.org/10.4081/cardio.2025.68
    3924
    PDF: 703
    Appendix: 470
    HTML: 40
  • Adherence to lifestyle therapy in patients with chronic heart failure and comorbidity

    Elena Efremova, Alexander Shutov
    2023-12-20
    https://doi.org/10.4081/cardio.2023.8
    1434
    pdf: 391
    HTML: 46
1 - 32 of 32 items

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iCARDIO

May 1 marked the release of the #iCARDIO Guidelines on Heart Failure, now live in Global Cardiology. This global-first effort brings flexible, practical guidance to frontline providers managing #heartfailure in any setting. www.globalcardiology.info/site/article... #GlobalHealth #cardiosky

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— iCardio (@icardio.bsky.social) May 13, 2025 at 8:26

Keywords

Vol. 4 No. 1 (2026)
Draft Document for Public Consultation: iCARDIO Alliance Global Implementation Guidelines on Ischemic Heart Disease Management 2026

Ischemic heart disease (IHD) remains the leading cause of morbidity and mortality worldwide.  Coronary artery disease (CAD) encompasses any pathological process capable of compromising myocardial perfusion and although numerous etiologies exist, including vasculitis, spontaneous coronary artery dissection, and coronary embolism, the majority of CAD is attributable to coronary atherosclerosis, which constitutes the focus of this document. For practical purposes, CAD is considered present when any degree of atherosclerotic involvement...

Writing Task Force | iCARDIO-Alliance
5 February 2026
Vol. 4 No. 2 (2026)
Filling the void: digoxin and the first randomized evidence in rheumatic heart disease

The Digoxin in Rheumatic Heart Disease (Dig-RHD) trial marks an important shift in rheumatic heart disease by replacing long-standing therapeutic assumption with direct randomized evidence. In a condition affecting predominantly young patients in low- and middle- income countries, practice has often relied on extrapolation from non-valvular heart failure populations despite clear differences in disease biology, treatment access, and clinical context. By reducing heart failure events in symptomatic patients, Dig-RHD suggests that the value...

Viana Copeland et al.
3 July 2026
Vol. 4 No. 2 (2026)
Familial hypercholesterolemia: state-of-the-art

Familial hypercholesterolemia (FH) affects about 20 million people worldwide and remains markedly underdiagnosed and undertreated. Contemporary studies estimate the prevalence of heterozygous FH (HeFH) at 1 in 192 to 1 in 310, and the prevalence of homozygous FH (HoFH) at about 1 in 300,000. The 2016 United States National Health and Nutrition Examination Survey estimated FH prevalence at 1 in 250 adults. Untreated HeFH causes fatal coronary events before age 55 in about 50% of men and before age 60 in about 15% of women. Pathogenic...

Ahmed Kamal Siddiqi et al.
29 June 2026
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