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Global Cardiology

eISSN 2975-2728

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Editor-in-Chief: Andrew J.S. Coats, Australia

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  • Aldosterone synthase inhibitors in cardio-renal diseases: a state-of-the-art review

    Muhammad Hamza Dawood, Muhammad Shahzeb Khan, Ahmed Mustafa Rashid, Wilhelm Haverkamp
    2025-12-31
    https://doi.org/10.4081/cardio.2025.91
    579
    PDF: 196
    HTML: 30
  • iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025 - Focus on prevention and treatment of cardiometabolic disease

    Stefan D. Anker, Linong Ji, Tammy Kindel, Andrew J.S. Coats, Dike Ojji, Adriana Puente Barragán, Peter Rossing, Shelley Zieroth, Shaaf Ahmad, Shariq Usman, Geeta Appannah, Alison L. Bailey, Ahmed Bennis, Andrea Brandao, Javed Butler, Melanie J. Davies, Lubomira Fabryova, Yuanlin Guo, Hidetaka Itoh, Uday M. Jadhav, Carel W. Le Roux, Fausto J. Pinto, Julio Rosenstock, Banshi Saboo, Hani Sabbour, Mangesh Tiwaskar, Karol E. Watson, Kwang Wei Tham, Fernando Stuardo Wyss Quintana, Walter P. Abhayaratna, William T. Abraham, Wael Al Mahmeed , Alessia Argirò, John J. Atherton, Danielle Belardo, Raquel Campuzano Ruiz, Nandini Chatterjee, Vijay Chopra, Marc-André Cornier, Sarah Davies, Clemencia de Rueda Panadero, Anastase Dzudie, Ty J. Gluckman, Muhammad Shahzeb Khan, Kamlesh Khunti, Yuri Lopatin, Zhiyi Ma, Okechukwu S. Ogah, Abraham Oomman, Emilio S. Peralta Lopez, Ping Li, Paul Poirier, Julie Redfern, Giuseppe M.C. Rosano, Donna Ryan, Amit Saraf, Sameh Shaheen, Subodh Verma, Stephan von Haehling, Yuhui Zhang, Martha Gulati, Naveed Sattar, José Luis Zamorano
    2025-09-30
    https://doi.org/10.4081/cardio.2025.86
    2924
    PDF: 3132
    Supplementary: 376
    Appendix: 305
  • Familial hypercholesterolemia: state-of-the-art

    Ahmed Kamal Siddiqi, Kumail Mustafa Ali, Rameen Shahid, Shamna Haris, Anandita Kulkarni, Iliyan Mithani, Wilhelm Haverkamp, Muhammad Shahzeb Khan
    2026-05-06
    https://doi.org/10.4081/cardio.2026.102
    83
    PDF: 24
    HTML: 1
  • Hypertension-related heart failure mortality among older adults in the United States: a nationwide analysis of demographic and regional trends

    Muhammad Muneeb Ur Rehman, Muhammad Sameer Arshad, Muhammad Abdul Tawab, Rahael Javaid, Sunil Modi, Marat Fudim
    2026-03-31
    https://doi.org/10.4081/cardio.2026.97
    606
    PDF: 183
    SUPPLEMENTARY FILES: 129
    HTML: 80
  • Demographic and regional trends of heart failure and cachexia-related mortality among older adults in the United States, from 1999 to 2020

    Ishaque Hameed, Muhammad Nashit, Zahra Quettawala Mufaddal, Syed Sarmad Javaid, Muhammad Hanif
    2025-09-19
    https://doi.org/10.4081/cardio.2025.83
    445
    PDF: 271
    HTML: 63
  • Glucagon-like peptide-1 receptor agonists and muscle: interpreting lean mass changes in clinical care

    Muhammad Sameer Arshad, Maaz Ali, Asad Ali Ahmed Cheema, Stefan D. Anker, Andrew J.S. Coats
    2026-03-31
    https://doi.org/10.4081/cardio.2026.101
    599
    PDF: 235
    HTML: 86
  • The impact of diurnal fasting during Ramadan on patients with established cardiac disease: a systematic review

    Marwan M. Refaat, Nadim El Jamal, Hebah M. El-Rayess, Anthony Gebran, Amar M. Salam
    2024-06-28
    https://doi.org/10.4081/cardio.2024.32
    3045
    PDF: 1200
    HTML: 22
  • Effect of metformin and empagliflozin on myocardial function in insulin-resistant patients with heart failure: rationale and design of the METRIS-HF-DZHK18 Trial

    Wolfram Doehner, Tim Friede, Frank Edelmann, Ulf Landmesser, Sebastian Winkler, Burkert Pieske, Fabian Knebel, Sebastian Kelle, Diethelm Tschöpe, Antje Meyer, Nadja Jauert, Marius Placzek, Jeanette Schulz-Menger, Stephan von Haehling, Stefan D. Anker
    2025-12-31
    https://doi.org/10.4081/cardio.2025.89
    347
    PDF: 109
    Appendix: 33
    HTML: 11
  • Coronary artery calcium scoring. What clinicians need to know

    Syeda Sundus Shah Bokharii, Cristiana Vitale, Eman Khan, Giuseppe M.C. Rosano, Laibah Arshad Khan
    2025-12-11
    https://doi.org/10.4081/cardio.2025.87
    1949
    PDF: 565
    HTML: 233
  • Cardiac wasting in patients with advanced cancer: state of the art review

    Laibah Arshad Khan, Muhammad Shahzeb Khan, Rania Usman Latif, Markus S. Anker
    2025-04-16
    https://doi.org/10.4081/cardio.2025.65
    2798
    PDF: 653
    HTML: 65
  • Patent foramen ovale: when does it need closure?

    Aimen Shafiq, Richard A. Krasuski
    2026-03-31
    https://doi.org/10.4081/cardio.2026.98
    519
    PDF: 164
    HTML: 94
  • Applicability of obesity clinical practice guidelines in low- and middle-income countries

    Shelley Zieroth, Fausto Pinto, Stefan D. Anker, William T. Abraham, John J. Atherton, Javed Butler, Vijay Chopra, Andrew J.S. Coats, Martha Gulati, Tammy L. Kindel, José Luis Zamorano, Yuhui Zhang, Linong Ji, Yann Colardelle, Richard B. Weiskopf
    2025-06-30
    https://doi.org/10.4081/cardio.2025.77
    1529
    PDF: 753
    Appendix: 272
    HTML: 42
  • Metabolic dysfunction-associated steatotic liver disease and cardiovascular disease: a state-of-the-art review

    Aimen Shafiq, Ahmed Mustafa Rashid, Syed Raza Shah, Nicholas W.S. Chew, Wilhelm Haverkamp
    2026-04-10
    https://doi.org/10.4081/cardio.2026.94
    1786
    PDF: 724
    HTML: 118
  • Safety and efficacy of left atrial appendage closure in cancer versus non-cancer patients: a systematic review and meta-analysis

    Muhammad Ahmed, Fatima Muskan, Mohsin Zaheer, Manesh Kumar, Sawera Gul, Abdul Hadi Ansari, Muhammad Sameer Jamal, Muhammad Sohaib Asghar, M. Chadi Alraies, Shiny Teja Kolli, Praveen Kumar Komminni, Priya Hotwani, Vishal Reddy Bejugam
    2025-06-30
    https://doi.org/10.4081/cardio.2025.72
    1279
    PDF: 352
    Supplementary: 184
    HTML: 151
  • Dyslipidemia and stroke-related mortality in the United States: a nationwide analysis for 2010-2020

    Muhammad Muneeb Ur Rehman, Iliyan Mithani, Muhammad Sameer Arshad, Syed Raza Shah, Wolfram Doehner, Anandita Kulkarni
    2025-12-31
    https://doi.org/10.4081/cardio.2025.90
    412
    PDF: 130
    Supplementary: 38
    HTML: 32
  • Ischemic and bleeding outcomes by diabetes status in patients receiving ticagrelor monotherapy after percutaneous coronary intervention: an updated meta-analysis

    Muhammad Ahmed, Faiqa Iqbal, Muhammad Talha Safdar, Barka Sajid, Muhammad Ahmed Ali Fahim, Salim Surani
    2026-03-31
    https://doi.org/10.4081/cardio.2026.99
    400
    PDF: 164
    SUPPLEMENTARY FILES: 132
    HTML: 57
  • Global Cardiology issue highlights

    Andrew J.S. Coats
    2024-06-28
    https://doi.org/10.4081/cardio.2024.41
    3587
    PDF: 443
    HTML: 0
  • Detection of early heart failure with preserved ejection fraction in metabolic syndrome patients detected as part of a national screening program in middle aged subjects

    Jelena Čelutkienė, Agnė Monika Jakštaitė, Jolita Badarienė, Svetlana Solovjova, Ieva Slivovskaja, Rokas Navickas, Edita Kazėnaitė, Egidija Rinkūnienė, Alma Čypienė, Jonas Misiūra, Ligita Ryliškytė, Aleksandras Laucevičius, Andrew J.S. Coats
    2023-12-29
    https://doi.org/10.4081/cardio.2023.3
    1704
    pdf: 326
    HTML: 13
  • Elevated endostatin is associated with hypertension treatment, elevated high sensitivity C-reactive protein, increased waist-hip ratio, and attenuated kidney function, but not with age, in a middle-aged population

    Anders Larsson, Bertil Wegmann, Toralph Ruge, Joakim Alfredsson, Carl Johan Östgren, Tomas Lindahl
    2025-04-16
    https://doi.org/10.4081/cardio.2025.64
    2789
    PDF: 548
    HTML: 11
  • Beyond trial neutrality: treatment discontinuation and the hidden signal in SPIRIT-HF trial

    Viana Copeland, Andrew J.S. Coats
    2026-03-31
    https://doi.org/10.4081/cardio.2026.100
    560
    PDF: 194
    HTML: 99
  • The impact of frailty on in-hospital outcomes in patients with HFrEF

    Saad Ahmed Waqas, Taimor Mohammed Khan, Ahmed Kamal Siddiqi, Shahzad Hassan, Stefan D. Anker
    2025-12-17
    https://doi.org/10.4081/cardio.2025.88
    496
    PDF: 176
    Supplementary: 52
    HTML: 21
  • The effect of sauna on cardiac and skeletal muscle function in patients with HFpEF (SAUNA-HFpEF): rationale and design

    Tarek Bekfani, Kris G. Vargas, Flor Gomez, Alexander Schmeisser, Ruediger C. Braun-Dullaeus
    2025-06-30
    https://doi.org/10.4081/cardio.2025.67
    2693
    PDF: 548
    HTML: 138
  • Epidemiology of peripartum cardiomyopathy in Africa

    Kamilu M. Karaye, Abdulrazaq G. Habib, Karen Sliwa
    2024-06-28
    https://doi.org/10.4081/cardio.2024.31
    2578
    PDF: 558
    HTML: 143
  • Is the obesity paradox present in left ventricular assist device recipients? A BMI-based analysis

    Saad Ahmed Waqas, Hibah Siddiqui, Faouzi Kallel, Shahzad Hassan
    2025-09-30
    https://doi.org/10.4081/cardio.2025.84
    314
    PDF: 336
    Supplementary: 166
    HTML: 43
  • Welcome to Global Cardiology

    Andrew J.S. Coats
    2023-12-20
    https://doi.org/10.4081/cardio.2023.1
    2540
    pdf: 199
    HTML: 4
  • Baseline echocardiographic characteristics of patients enrolled in the randomized investigation of MitraClip device in heart failure (RESHAPE HF-2) trial: comparison with COAPT and Mitra-FR

    Ralph Stephan von Bardeleben, Muhammad Shahzeb Khan, Martin Geyer, Tim Friede, Javed Butler, Monika Diek, Jutta Heinrich, Marius Placzek, Roberto Ferrari, William T. Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G.F. Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo P. Maggioni, Marco Metra, Vlasis Ninios, Mark C. Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P. Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K. Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J. Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias Friedrich Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski, Stefan D. Anker
    2024-06-28
    https://doi.org/10.4081/cardio.2024.40
    5661
    PDF: 850
    HTML: 49
  • Bridging the gap: integrating stress echocardiography, iFR, CFR, and FFR in the evaluation of coronary artery disease

    Konstantinos Stamos, Theodora Delaporta, Antonios Delaportas
    2025-04-16
    https://doi.org/10.4081/cardio.2025.66
    1574
    PDF: 490
    HTML: 0
  • Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

    Markus S. Anker, Sven Bercker, Ulrich Laufs, Michael Böhm, Bela Merkely, Monika Diek, Tim Heise, Martin Hellmich, Marius Placzek, Tim Friede, Stefan D. Anker, Lorenz Lehmann, Ulf Landmesser, Dominik P. Modest, Muhammad Shahzeb Khan, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes, Muhammad Sameer Arshad, Raluca Mincu, Javed Butler, Ulrich Keller, Johann Ahn, Lars Bullinger, Tienush Rassaf
    2025-08-20
    https://doi.org/10.4081/cardio.2025.78
    550
    PDF: 448
    Appendix: 235
    HTML: 69
  • Exercise capacity, iron deficiency and depressive symptoms in patients with asymptomatic chronic systolic heart failure

    Sven Christopher Aland, Christoph Gertler, Hannah Leonie Bräunig, Timo Schröder, Frank Edelmann, Rolf Wachter, Christoph Herrmann-Lingen, Gerd Hasenfuß, Anja Sandek
    2024-06-28
    https://doi.org/10.4081/cardio.2024.39
    1730
    PDF: 541
    HTML: 11
  • Aortic valve replacement in asymptomatic severe aortic stenosis. A focused review

    Aimen Shafiq, Rohan Dev Trehan, Mitja Lainscak, Sanjeev Trehan
    2025-12-31
    https://doi.org/10.4081/cardio.2025.93
    332
    PDF: 132
    HTML: 11
  • Large language models to write scientific manuscripts: to be considered but not trusted

    Christian Basile, Stefan D. Anker, Gianluigi Savarese
    2025-06-30
    https://doi.org/10.4081/cardio.2025.74
    886
    PDF: 313
    HTML: 13
  • Prevalence of left ventricular dysfunction and relationship with serum selenium in apparently healthy pregnant women: results from the PEACE registry

    Kamilu M. Karaye, Idris Y. Mohammed, Hadiza Sa’idu, Naser A. Ishaq, Suleiman A. Balarabe, Jamilu Tukur, Tewogbade A. Adedeji, Olufemiwa N. Makinde, Rasaaq A. Adebayo
    2024-06-28
    https://doi.org/10.4081/cardio.2024.36
    1685
    PDF: 450
    HTML: 9
  • Impella vs intra-aortic balloon pump in patients with acute myocardial infarction complicated with cardiogenic shock: an updated systematic review and meta-analysis

    Muhammad Ahmed, Serish Bano, Mutahira Asif, F.N.U. Sidra, Meva Ram, Shahida Bibi
    2025-04-16
    https://doi.org/10.4081/cardio.2025.61
    4393
    PDF: 863
    Supplementary: 423
    HTML: 0
  • The effect of SGLT2 inhibitors on health status in patients with heart failure: a systematic review and meta-analysis

    Muhammad Shariq Usman, Arsalan Hamid, Shurjeel Uddin Qazi, Mikhail N. Kosiborod, Deepak L. Bhatt, Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler
    2024-06-28
    https://doi.org/10.4081/cardio.2024.35
    3018
    PDF: 740
    Conflict of interest: 340
    SUPPLEMENTARY MATERIAL: 284
    HTML: 83
  • Depression, health-related quality of life and life satisfaction in patients with heart failure

    Natasa Sedlar Kobe, Daniel Omersa, Mitja Lainscak, Jerneja Farkas
    2024-11-05
    https://doi.org/10.4081/cardio.2024.47
    3036
    PDF: 789
    HTML: 8
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iCARDIO

May 1 marked the release of the #iCARDIO Guidelines on Heart Failure, now live in Global Cardiology. This global-first effort brings flexible, practical guidance to frontline providers managing #heartfailure in any setting. www.globalcardiology.info/site/article... #GlobalHealth #cardiosky

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— iCardio (@icardio.bsky.social) May 13, 2025 at 8:26

Keywords

Vol. 4 No. 1 (2026)
Draft Document for Public Consultation: iCARDIO Alliance Global Implementation Guidelines on Ischemic Heart Disease Management 2026

Ischemic heart disease (IHD) remains the leading cause of morbidity and mortality worldwide.  Coronary artery disease (CAD) encompasses any pathological process capable of compromising myocardial perfusion and although numerous etiologies exist, including vasculitis, spontaneous coronary artery dissection, and coronary embolism, the majority of CAD is attributable to coronary atherosclerosis, which constitutes the focus of this document. For practical purposes, CAD is considered present when any degree of atherosclerotic involvement...

Writing Task Force | iCARDIO-Alliance
5 February 2026
Vol. 4 No. 1 (2026)
Metabolic dysfunction-associated steatotic liver disease and cardiovascular disease: a state-of-the-art review

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly nonalcoholic fatty liver disease, is the most prevalent chronic liver disease worldwide, affecting more than 30% of adults and up to 70–90% of individuals with obesity or type 2 diabetes mellitus. Cardiovascular disease (CVD) represents the leading cause of mortality in this population. MASLD is increasingly recognized as an independent cardiovascular risk factor beyond traditional metabolic comorbidities. This narrative review summarizes epidemiologic,...

Aimen Shafiq et al.
10 April 2026
Global Cardiology

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